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Cellular phenotype is characterized by different components such as cell size, protein content and cell cycle time. These are global variables that are the outcome of multiple internal microscopic processes. Accordingly, they display some…

Cell Behavior · Quantitative Biology 2018-05-16 Lee Susman , Maryam Kohram , Harsh Vashistha , Jeffrey T. Nechleba , Hanna Salman , Naama Brenner

The spatiotemporal oscillations of the Min proteins in the bacterium Escherichia coli play an important role in cell division. A number of different models have been proposed to explain the dynamics from the underlying biochemistry. Here,…

Subcellular Processes · Quantitative Biology 2013-05-29 Peter Borowski , Eric N. Cytrynbaum

We consider a discrete model of population with interaction where the birth and death rates are non linear functions of the population size. After proceeding to renormalization of the model parameters, we obtain in the limit of large…

Probability · Mathematics 2015-11-11 Mamadou Ba , Etienne Pardoux

A fissioning organism may purge unrepairable damage by bequeathing it preferentially to one of its daughters. Using the mathematical formalism of superprocesses, we propose a flexible class of analytically tractable models that allow quite…

Populations and Evolution · Quantitative Biology 2007-05-23 Steven N. Evans , David Steinsaltz

In this paper, we analyse a model for the growth of three-dimensional walled cells. In this model the biomechanical expansion of the cell is coupled with the geometry of its wall. We consider that the density of building material depends on…

Analysis of PDEs · Mathematics 2015-02-20 Vincent Calvez , Laetitia Giraldi

This paper presents a batch-wise density-based clustering approach for local outlier detection in massive-scale datasets. Unlike the well-known traditional algorithms, which assume that all the data is memory-resident, our proposed method…

Machine Learning · Computer Science 2021-07-06 Sayyed Ahmad Naghavi Nozad , Maryam Amir Haeri , Gianluigi Folino

Mathematical modelling for population growth leads to a differential equation. In population growth model, we assume that rate increase of population is proportional to current population. That is, dx / dt = kx, x is a current population, k…

General Mathematics · Mathematics 2017-12-12 U. M. Pirzada

Diffusion models generate high-quality synthetic data. They operate by defining a continuous-time forward process which gradually adds Gaussian noise to data until fully corrupted. The corresponding reverse process progressively "denoises"…

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

While diffusion models have achieved great success in generating continuous signals such as images and audio, it remains elusive for diffusion models in learning discrete sequence data like natural languages. Although recent advances…

Computation and Language · Computer Science 2024-05-02 Jiasheng Ye , Zaixiang Zheng , Yu Bao , Lihua Qian , Mingxuan Wang

Spontaneous stratification of granular mixtures has been reported by Makse et al. [Nature 386, 379 (1997)] when a mixture of grains differing in size and shape is poured in a quasi-two-dimensional heap. We study this phenomenon using two…

Statistical Mechanics · Physics 2009-10-31 Pierre Cizeau , Hernan A. Makse , H. Eugene Stanley

Protein concentration in a living cell fluctuates over time due to noise in growth and division processes. From extensive single-cell experiments by using E. coli strains with different promoter strength (over two orders of magnitude) and…

Biological Physics · Physics 2021-04-19 Alberto Stefano Sassi , Mayra Garcia-Alcala , Philippe Cluzel , Yuhai Tu

The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…

Analysis of PDEs · Mathematics 2009-11-11 Carlos Escudero

In this paper we present a generalized model for network growth that links the microscopical agent strategies with the large scale behavior. This model is intended to reproduce the largest number of features of the Internet network at the…

Statistical Mechanics · Physics 2007-05-23 Guido Caldarelli , Paolo De Los Rios , Luciano Pietronero

In population biology, the Allee dynamics refer to negative growth rates below a critical population density. In this Letter, we study a reaction-diffusion (RD) model of population growth and dispersion in one dimension, which incorporates…

Cell Behavior · Quantitative Biology 2017-08-02 Indrani Bose , Mainak Pal , Chiranjit Karmakar

Diffusion models learn to denoise data and the trained denoiser is then used to generate new samples from the data distribution. In this paper, we revisit the diffusion sampling process and identify a fundamental cause of sample quality…

Machine Learning · Computer Science 2024-11-05 Yunshu Wu , Yingtao Luo , Xianghao Kong , Evangelos E. Papalexakis , Greg Ver Steeg

We consider the mean-field approximation of an individual-based model describing cell motility and proliferation, which incorporates the volume exclusion principle, the go-or-grow hypothesis and an explicit cell cycle delay. To utilise the…

Cell Behavior · Quantitative Biology 2019-03-05 Ruth E. Baker , Péter Boldog , Gergely Röst

We study the mathematical properties of a general model of cell division structured with several internal variables. We begin with a simpler and specific model with two variables, we solve the eigenvalue problem with strong or weak…

Analysis of PDEs · Mathematics 2008-10-08 Marie Doumic Jauffret

Granular materials segregate by size under shear, and the ability to quantitatively predict the time required to achieve complete segregation is a key test of our understanding of the segregation process. In this paper, we apply the…

Soft Condensed Matter · Physics 2015-05-14 Lindsay B. H. May , Laura A. Golick , Katherine C. Phillips , Michael Shearer , Karen E. Daniels

We propose a kind of reaction-diffusion equations for cell differentiation, which exhibits the Turing instability. If the diffusivity of some variables is set to be infinity, we get coupled competitive reaction-diffusion equations with a…

Cell Behavior · Quantitative Biology 2015-05-13 Hidetsugu Sakaguchi
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