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A key hurdle is demonstrating compute resource capability with limited benchmarks. We propose workflow templates as a solution, offering adaptable designs for specific scientific applications. Our paper identifies common usage patterns for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-31 Gregor von Laszewski , Wesley Brewer , Sean R. Wilkinson , Andrew Shao , J. P. Fleischer , Harshad Pitkar , Christine R. Kirkpatrick , Geoffrey C. Fox

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

We present a workflow for clinical data analysis that relies on Bayesian Structure Learning (BSL), an unsupervised learning approach, robust to noise and biases, that allows to incorporate prior medical knowledge into the learning process…

Machine Learning · Computer Science 2022-10-12 Elisa Ferrari , Luna Gargani , Greta Barbieri , Lorenzo Ghiadoni , Francesco Faita , Davide Bacciu

The formation of biomolecular materials via dynamical interfacial processes such as self-assembly and fusion, for diverse compositions and external conditions, can be efficiently probed using ensemble Molecular Dynamics. However, this…

In this thesis first we propose an intermediate data management scheme for a SWfMS. In our second attempt, we explored the possibilities and introduced an automatic recommendation technique for a SWfMS from real-world workflow data (i.e…

Information Retrieval · Computer Science 2020-10-28 Debasish Chakroborti

Life is a nonequilibrium phenomenon: metabolism provides a continuous supply of energy that drives nearly all cellular processes. However, very little is known about how much energy different cellular processes use, i.e. their energetic…

Biological Physics · Physics 2023-03-29 Easun Arunachalam , William Ireland , Xingbo Yang , Dan Needleman

Scientific workflow management systems (SWMSs) and resource managers together ensure that tasks are scheduled on provisioned resources so that all dependencies are obeyed, and some optimization goal, such as makespan minimization, is…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-17 Fabian Lehmann , Jonathan Bader , Friedrich Tschirpke , Lauritz Thamsen , Ulf Leser

Climate science is critical for understanding both the causes and consequences of changes in global temperatures and has become imperative for decisive policy-making. However, climate science studies commonly require addressing complex…

Machine Learning · Computer Science 2020-09-23 Juan Carrillo , Daniel Garijo , Mark Crowley , Rober Carrillo , Yolanda Gil , Katherine Borda

One of the main challenges for biomedical research lies in the computer-assisted integrative study of large and increasingly complex combinations of data in order to understand molecular mechanisms. The preservation of the materials and…

Background: Security tools play a vital role in enabling developers to build secure software. However, it can be quite challenging to introduce and fully leverage security tools without affecting the speed or frequency of deployments in the…

Cryptography and Security · Computer Science 2021-07-20 Roshan Namal Rajapakse , Mansooreh Zahedi , Muhammad Ali Babar

The "IMP Science Gateway Portal" (http://scigate.imp.kiev.ua) for complex workflow management and integration of distributed computing resources (like clusters, service grids, desktop grids, clouds) is presented. It is created on the basis…

Computational Engineering, Finance, and Science · Computer Science 2014-04-23 Yuri Gordienko , Lev Bekenov , Olexandr Gatsenko , Elena Zasimchuk , Valentin Tatarenko

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Collaborative scientific authoring is increasingly being supported by software tools. Traditionally, desktop-based authoring tools had the most advanced editing features, allowed for more formatting options, and included more import/export…

Digital Libraries · Computer Science 2018-04-23 Afshin Sadeghi , Mahdi Jaberzadeh Ansari , Johannes Wilm , Christoph Lange

Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount…

Biomolecules · Quantitative Biology 2023-07-24 Yizhen Luo , Kai Yang , Massimo Hong , Xing Yi Liu , Zaiqing Nie

Sound data analysis is essential to retrieve meaningful biological information from single-cell proteomics experiments. This analysis is carried out by computational methods that are assembled into workflows, and their implementations…

Quantitative Methods · Quantitative Biology 2022-12-02 Christophe Vanderaa , Laurent Gatto

Modern biological research is increasingly data-intensive, leading to a growing demand for effective training in biological data science. In this article, we provide an overview of key resources and best practices available within the…

Scientific Workflow Systems such as Galaxy and Nextflow are essential for scalable, reproducible, and automated bioinformatics analyses. However, developing and understanding scientific workflows remains challenging for many domain…

Software Engineering · Computer Science 2025-08-18 Khairul Alam , Banani Roy

While mechanobiology has demonstrated that precise control over mechanical properties at the whole-cell level is crucial for many biological functions, comparatively little attention has been paid to the intracellular mechanical properties.…

Subcellular Processes · Quantitative Biology 2025-01-27 Mohammad Amin Eskandari , Jannis Fischer , Noémie Veyret , Dorian Marx , Timo Betz

Experimental science is enabled by the combination of synthesis, imaging, and functional characterization. Synthesis of a new material is typically followed by a set of characterization methods aiming to provide feedback for optimization or…

Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…

Artificial Intelligence · Computer Science 2014-03-04 Saadat Anwar
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