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We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Image segmentation is a long-standing challenge in computer vision, studied continuously over several decades, as evidenced by seminal algorithms such as N-Cut, FCN, and MaskFormer. With the advent of foundation models (FMs), contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Tianfei Zhou , Wang Xia , Fei Zhang , Boyu Chang , Wenguan Wang , Ye Yuan , Ender Konukoglu , Daniel Cremers

Medical image segmentation, the task of partitioning an image into meaningful parts, is an important step toward automating medical image analysis and is at the crux of a variety of medical imaging applications, such as computer aided…

Computer Vision and Pattern Recognition · Computer Science 2016-07-06 Masoud S. Nosrati , Ghassan Hamarneh

Segmentation of nanoscale electron microscopy (EM) images is crucial but still challenging in connectomics research. One reason for this is that none of the existing segmentation methods are error-free, so they require proofreading, which…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Khoa Tuan Nguyen , Ganghee Jang , Tran Anh Tuan , Won-ki Jeong

We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

In recent years, Convolutional Neural Networks (CNNs) have become the state-of-the-art method for biomedical image analysis. However, these networks are usually trained in a supervised manner, requiring large amounts of labelled training…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Nastassya Horlava , Alisa Mironenko , Sebastian Niehaus , Sebastian Wagner , Ingo Roeder , Nico Scherf

Recent innovations in light sheet microscopy, paired with developments in tissue clearing techniques, enable the 3D imaging of large mammalian tissues with cellular resolution. Combined with the progress in large-scale data analysis, driven…

Segmenting medical images is critical to facilitating both patient diagnoses and quantitative research. A major limiting factor is the lack of labeled data, as obtaining expert annotations for each new set of imaging data and task can be…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Chen Liu , Matthew Amodio , Liangbo L. Shen , Feng Gao , Arman Avesta , Sanjay Aneja , Jay C. Wang , Lucian V. Del Priore , Smita Krishnaswamy

Due to the limitation of available labeled data, medical image segmentation is a challenging task for deep learning. Traditional data augmentation techniques have been shown to improve segmentation network performances by optimizing the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Kevin Ginsburger

Segmentation of distinct bones plays a crucial role in diagnosis, planning, navigation, and the assessment of bone metastasis. It supplies semantic knowledge to visualisation tools for the planning of surgical interventions and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-15 Eva Schnider , Antal Horváth , Georg Rauter , Azhar Zam , Magdalena Müller-Gerbl , Philippe C. Cattin

Segmentation of cell nuclei in microscopy images is a prevalent necessity in cell biology. Especially for three-dimensional datasets, manual segmentation is prohibitively time-consuming, motivating the need for automated methods.…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Peter Hirsch , Dagmar Kainmueller

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Sota Kato , Kazuhiro Hotta

Today, deep convolutional neural networks (CNNs) have demonstrated state of the art performance for supervised medical image segmentation, across various imaging modalities and tasks. Despite early success, segmentation networks may still…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Rosana El Jurdi , Caroline Petitjean , Paul Honeine , Veronika Cheplygina , Fahed Abdallah

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

From the autonomous car driving to medical diagnosis, the requirement of the task of image segmentation is everywhere. Segmentation of an image is one of the indispensable tasks in computer vision. This task is comparatively complicated…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Farhana Sultana , Abu Sufian , Paramartha Dutta

Medical imaging is a cornerstone of modern healthcare, driving advancements in diagnosis, treatment planning, and patient care. Among its various tasks, segmentation remains one of the most challenging problem due to factors such as data…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Fares Bougourzi , Abdenour Hadid

Deep neural networks currently deliver promising results for microscopy image cell segmentation, but they require large-scale labelled databases, which is a costly and time-consuming process. In this work, we relax the labelling requirement…

Computer Vision and Pattern Recognition · Computer Science 2022-08-04 Youssef Dawoud , Katharina Ernst , Gustavo Carneiro , Vasileios Belagiannis
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