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In recent years, Deep Learning (DL) has shown promising results in conducting AI tasks such as computer vision and image segmentation. Specifically, Convolutional Neural Network (CNN) models in DL have been applied to prevention,detection,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ahmed Awad Albishri , Syed Jawad Hussain Shah , Anthony Schmiedler , Seung Suk Kang , Yugyung Lee

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

We present two practical improvement techniques for unsupervised segmentation learning. These techniques address limitations in the resolution and accuracy of predicted segmentation maps of recent state-of-the-art methods. Firstly, we…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Alp Eren Sari , Francesco Locatello , Paolo Favaro

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

In this paper, we consider the problem of automatically segmenting neuronal cells in dual-color confocal microscopy images. This problem is a key task in various quantitative analysis applications in neuroscience, such as tracing cell…

Computer Vision and Pattern Recognition · Computer Science 2017-06-01 Jianxu Chen , Sreya Banerjee , Abhinav Grama , Walter J. Scheirer , Danny Z. Chen

Medical image segmentation plays a crucial role in clinical diagnosis and treatment planning, where accurate boundary delineation is essential for precise lesion localization, organ identification, and quantitative assessment. In recent…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Peiting Tian , Xi Chen , Haixia Bi , Fan Li

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Accurate cell segmentation is critical for biological and medical imaging studies. Although recent deep learning models have advanced this task, most methods are limited to generic cell segmentation, lacking the ability to differentiate…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Bisheng Wang , Jaime S. Cardoso , Lin Wu

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

We have developed an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells inspired by a multi-resolution community detection (MCD) based network segmentation method. The image processing…

Medical Physics · Physics 2014-01-06 Dandan Hu , Pinaki Sarder , Peter Ronhovde , Sandra Orthaus , Samuel Achilefu , Zohar Nussinov

We aim to improve segmentation through the use of machine learning tools during region agglomeration. We propose an active learning approach for performing hierarchical agglomerative segmentation from superpixels. Our method combines…

Computer Vision and Pattern Recognition · Computer Science 2015-03-13 Juan Nunez-Iglesias , Ryan Kennedy , Toufiq Parag , Jianbo Shi , Dmitri B. Chklovskii

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

We present a novel method for cell segmentation in microscopy images which is inspired by the Generative Adversarial Neural Network (GAN) approach. Our framework is built on a pair of two competitive artificial neural networks, with a…

Computer Vision and Pattern Recognition · Computer Science 2018-09-14 Assaf Arbelle , Tammy Riklin Raviv

In clinical practice, regions of interest in medical imaging often need to be identified through a process of precise image segmentation. The quality of this image segmentation step critically affects the subsequent clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-23 João B. S. Carvalho , João A. Santinha , Đorđe Miladinović , Joachim M. Buhmann

In the field of transmission electron microscopy, data interpretation often lags behind acquisition methods, as image processing methods often have to be manually tailored to individual datasets. Machine learning offers a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 C. K. Groschner , Christina Choi , M. C. Scott

Image semantic segmentation is more and more being of interest for computer vision and machine learning researchers. Many applications on the rise need accurate and efficient segmentation mechanisms: autonomous driving, indoor navigation,…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Alberto Garcia-Garcia , Sergio Orts-Escolano , Sergiu Oprea , Victor Villena-Martinez , Jose Garcia-Rodriguez

Extracting a connectome from an electron microscopy (EM) data set requires identification of neurons and determination of synapses between neurons. As manual extraction of this information is very time-consuming, there has been extensive…

Computer Vision and Pattern Recognition · Computer Science 2016-04-12 Gary B. Huang , Louis K. Scheffer , Stephen M. Plaza

Recent advances in deep learning have improved the segmentation accuracy of subcortical brain structures, which would be useful in neuroimaging studies of many neurological disorders. However, most of the previous deep learning work does…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Yilin Liu , Gengyan Zhao , Brendon M. Nacewicz , Nagesh Adluru , Gregory R. Kirk , Peter A Ferrazzano , Martin Styner , Andrew L. Alexander

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Anwai Archit , Constantin Pape
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