English
Related papers

Related papers: A Multi-Task Learning Framework for Extracting Dru…

200 papers

Social media has grown to be a crucial information source for pharmacovigilance studies where an increasing number of people post adverse reactions to medical drugs that are previously unreported. Aiming to effectively monitor various…

Machine Learning · Computer Science 2018-02-19 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

The identification of drug-target interactions (DTI) is critical for drug discovery and repositioning, as it reveals potential therapeutic uses of existing drugs, accelerating development and reducing costs. However, most existing models…

Machine Learning · Computer Science 2025-07-22 Xiang Zhao , Ruijie Li , Qiao Ning , Shikai Guo , Hui Li , Qian Ma

Motivation: Automatic Anatomical Therapeutic Chemical (ATC) classification is a critical and highly competitive area of research in bioinformatics because of its potential for expediting drug develop-ment and research. Predicting an unknown…

Quantitative Methods · Quantitative Biology 2021-08-09 Loris Nanni , Alessandra Lumini , Sheryl Brahnam

Accurate prediction of drug-target interaction (DTI) is essential for in silico drug design. For the purpose, we propose a novel approach for predicting DTI using a GNN that directly incorporates the 3D structure of a protein-ligand…

Machine Learning · Computer Science 2019-04-18 Jaechang Lim , Seongok Ryu , Kyubyong Park , Yo Joong Choe , Jiyeon Ham , Woo Youn Kim

Drug-target relationships may now be predicted computationally using bioinformatics data, which is a valuable tool for understanding pharmacological effects, enhancing drug development efficiency, and advancing related research. A number of…

Machine Learning · Computer Science 2024-07-16 Yuhuan Zhou , Yulin Wu , Weiwei Yuan , Xuan Wang , Junyi Li

Accurately predicting drug-drug interactions (DDI) for emerging drugs, which offer possibilities for treating and alleviating diseases, with computational methods can improve patient care and contribute to efficient drug development.…

Quantitative Methods · Quantitative Biology 2023-11-17 Yongqi Zhang , Quanming Yao , Ling Yue , Xian Wu , Ziheng Zhang , Zhenxi Lin , Yefeng Zheng

We study the problem of named entity recognition (NER) from electronic medical records, which is one of the most fundamental and critical problems for medical text mining. Medical records which are written by clinicians from different…

Computation and Language · Computer Science 2018-05-01 Zhenghui Wang , Yanru Qu , Liheng Chen , Jian Shen , Weinan Zhang , Shaodian Zhang , Yimei Gao , Gen Gu , Ken Chen , Yong Yu

In silico prediction of drug-target interactions (DTI) is significant for drug discovery because it can largely reduce timelines and costs in the drug development process. Specifically, deep learning-based DTI approaches have been shown…

Machine Learning · Computer Science 2021-09-20 Yeachan Kim , Bonggun Shin

Adverse drug reaction (ADR) prediction plays a crucial role in both health care and drug discovery for reducing patient mortality and enhancing drug safety. Recently, many studies have been devoted to effectively predict the drug-ADRs…

Information Retrieval · Computer Science 2023-08-08 Haoxuan Li , Taojun Hu , Zetong Xiong , Chunyuan Zheng , Fuli Feng , Xiangnan He , Xiao-Hua Zhou

Named entity recognition (NER) aims to identify mentions of named entities in an unstructured text and classify them into predefined named entity classes. While deep learning-based pre-trained language models help to achieve good predictive…

Computation and Language · Computer Science 2023-06-16 Ali Osman Berk Sapci , Oznur Tastan , Reyyan Yeniterzi

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this…

Computation and Language · Computer Science 2023-11-21 Ilseyar Alimova , Elena Tutubalina

In multi-label text classification (MLTC), each given document is associated with a set of correlated labels. To capture label correlations, previous classifier-chain and sequence-to-sequence models transform MLTC to a sequence prediction…

Computation and Language · Computer Science 2021-06-08 Ximing Zhang , Qian-Wen Zhang , Zhao Yan , Ruifang Liu , Yunbo Cao

Drug-target interaction (DTI) prediction is a critical component of the drug discovery process. In the drug development engineering field, predicting novel drug-target interactions is extremely crucial.However, although existing methods…

Biomolecules · Quantitative Biology 2024-05-24 Hongzhi Zhang , Xiuwen Gong , Shirui Pan , Jia Wu , Bo Du , Wenbin Hu

With the rapid development of high-throughput technologies, parallel acquisition of large-scale drug-informatics data provides huge opportunities to improve pharmaceutical research and development. One significant application is the purpose…

Machine Learning · Computer Science 2018-10-03 Lingwei Xie , Song He , Shu Yang , Boyuan Feng , Kun Wan , Zhongnan Zhang , Xiaochen Bo , Yufei Ding

Drug-target interaction (DTI) prediction, which aims at predicting whether a drug will be bounded to a target, have received wide attention recently, with the goal to automate and accelerate the costly process of drug design. Most of the…

Biomolecules · Quantitative Biology 2023-06-27 Shengming Zhang , Yizhou Sun

Named entity recognition has been extensively studied on English news texts. However, the transfer to other domains and languages is still a challenging problem. In this paper, we describe the system with which we participated in the first…

Computation and Language · Computer Science 2020-07-03 Lukas Lange , Heike Adel , Jannik Strötgen

Distant supervision based methods for entity and relation extraction have received increasing popularity due to the fact that these methods require light human annotation efforts. In this paper, we consider the problem of \textit{shifted…

Computation and Language · Computer Science 2020-04-22 Daoyuan Chen , Yaliang Li , Kai Lei , Ying Shen

Drug-drug interaction event (DDIE) prediction is crucial for preventing adverse reactions and ensuring optimal therapeutic outcomes. However, existing methods often face challenges with imbalanced datasets, complex interaction mechanisms,…

Machine Learning · Computer Science 2026-03-16 Pengfei Liu , Jun Tao , Zhixiang Ren

The NOESIS II challenge, as the Track 2 of the 8th Dialogue System Technology Challenges (DSTC 8), is the extension of DSTC 7. This track incorporates new elements that are vital for the creation of a deployed task-oriented dialogue system.…

Computation and Language · Computer Science 2020-04-07 Jia-Chen Gu , Tianda Li , Quan Liu , Xiaodan Zhu , Zhen-Hua Ling , Yu-Ping Ruan