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For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

The development of large language models tailored for handling patients' clinical notes is often hindered by the limited accessibility and usability of these notes due to strict privacy regulations. To address these challenges, we first…

Clinical notes often describe the most important aspects of a patient's physiology and are therefore critical to medical research. However, these notes are typically inaccessible to researchers without prior removal of sensitive protected…

Computation and Language · Computer Science 2018-03-08 Willie Boag , Tristan Naumann , Peter Szolovits

The difficulty of anonymizing text data hinders the development and deployment of NLP in high-stakes domains that involve private data, such as healthcare and social services. Poorly anonymized sensitive data cannot be easily shared with…

Computation and Language · Computer Science 2024-10-14 Krithika Ramesh , Nupoor Gandhi , Pulkit Madaan , Lisa Bauer , Charith Peris , Anjalie Field

A growing body of work uses Natural Language Processing (NLP) methods to automatically generate medical notes from audio recordings of doctor-patient consultations. However, there are very few studies on how such systems could be used in…

Generative models have been showing potential for producing data in mass. This study explores the enhancement of clinical natural language processing performance by utilizing synthetic data generated from advanced language models. Promising…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Jack Gallifant , Marco Guevara , Yanjun Gao , Majid Afshar , Timothy Miller , Dmitriy Dligach , Danielle S. Bitterman

Clinical patient notes are critical for documenting patient interactions, diagnoses, and treatment plans in medical practice. Ensuring accurate evaluation of these notes is essential for medical education and certification. However, manual…

Computation and Language · Computer Science 2024-01-25 Jingyu Xu , Yifeng Jiang , Bin Yuan , Shulin Li , Tianbo Song

Training data is fundamental to the success of modern machine learning models, yet in high-stakes domains such as healthcare, the use of real-world training data is severely constrained by concerns over privacy leakage. A promising solution…

To protect the privacy of individuals whose data is being shared, it is of high importance to develop methods allowing researchers and companies to release textual data while providing formal privacy guarantees to its originators. In the…

Machine Learning · Computer Science 2022-10-27 Justus Mattern , Zhijing Jin , Benjamin Weggenmann , Bernhard Schoelkopf , Mrinmaya Sachan

This study examines integrating EHRs and NLP with large language models (LLMs) to improve healthcare data management and patient care. It focuses on using advanced models to create secure, HIPAA-compliant synthetic patient notes for…

Computation and Language · Computer Science 2025-06-03 Yao-Shun Chuang , Atiquer Rahman Sarkar , Yu-Chun Hsu , Noman Mohammed , Xiaoqian Jiang

Synthetic data sets are used across linguistic domains and NLP tasks, particularly in scenarios where authentic data is limited (or even non-existent). One such domain is that of clinical (healthcare) contexts, where there exist significant…

Computation and Language · Computer Science 2026-03-17 Steven Bedrick , A. Seza Doğruöz , Sergiu Nisioi

A major obstacle to the development of Natural Language Processing (NLP) methods in the biomedical domain is data accessibility. This problem can be addressed by generating medical data artificially. Most previous studies have focused on…

Computation and Language · Computer Science 2019-08-09 Zixu Wang , Julia Ive , Sumithra Velupillai , Lucia Specia

Generating clinical synthetic text represents an effective solution for common clinical NLP issues like sparsity and privacy. This paper aims to conduct a systematic review on generating synthetic medical free-text by formulating…

Computation and Language · Computer Science 2025-07-25 Basel Alshaikhdeeb , Ahmed Abdelmonem Hemedan , Soumyabrata Ghosh , Irina Balaur , Venkata Satagopam

Comprehensive clinical documentation is crucial for effective healthcare delivery, yet it poses a significant burden on healthcare professionals, leading to burnout, increased medical errors, and compromised patient safety. This paper…

Artificial Intelligence · Computer Science 2024-05-29 Anjanava Biswas , Wrick Talukdar

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

The increasing use of synthetic data generated by Large Language Models (LLMs) presents both opportunities and challenges in data-driven applications. While synthetic data provides a cost-effective, scalable alternative to real-world data…

Computation and Language · Computer Science 2025-07-25 Tevin Atwal , Chan Nam Tieu , Yefeng Yuan , Zhan Shi , Yuhong Liu , Liang Cheng

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay…

Computation and Language · Computer Science 2023-04-12 Ruixiang Tang , Xiaotian Han , Xiaoqian Jiang , Xia Hu
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