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Predictive models allow subject-specific inference when analyzing disease related alterations in neuroimaging data. Given a subject's data, inference can be made at two levels: global, i.e. identifiying condition presence for the subject,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-18 Ender Konukoglu , Ben Glocker

Quantitative magnetic resonance imaging (qMRI) offers tissue-specific physical parameters with significant potential for neuroscience research and clinical practice. However, lengthy scan times for 3D multiparametric qMRI acquisition limit…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Guoyan Lao , Ruimin Feng , Haikun Qi , Zhenfeng Lv , Qiangqiang Liu , Chunlei Liu , Yuyao Zhang , Hongjiang Wei

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

Quantitative phase microscopy (QPM) is a label-free technique that enables to monitor morphological changes at subcellular level. The performance of the QPM system in terms of spatial sensitivity and resolution depends on the coherence…

Whole brain extraction, also known as skull stripping, is a process in neuroimaging in which non-brain tissue such as skull, eyeballs, skin, etc. are removed from neuroimages. Skull striping is a preliminary step in presurgical planning,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Sara Ranjbar , Kyle W. Singleton , Lee Curtin , Cassandra R. Rickertsen , Lisa E. Paulson , Leland S. Hu , J. Ross Mitchell , Kristin R. Swanson

One often lacks sufficient annotated samples for training deep segmentation models. This is in particular the case for less common imaging modalities such as Quantitative Susceptibility Mapping (QSM). It has been shown that deep models tend…

Magnetic Resonance Imaging (MRI) acquisitions require extensive scan times, limiting patient throughput and increasing susceptibility to motion artifacts. Accelerated parallel MRI techniques reduce acquisition time by undersampling k-space…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mingi Kang

Recent research has explored using neural networks to reconstruct undersampled magnetic resonance imaging (MRI) data. Because of the complexity of the artifacts in the reconstructed images, there is a need to develop task-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Joshua D. Herman , Rachel E. Roca , Alexandra G. O'Neill , Marcus L. Wong , Sajan G. Lingala , Angel R. Pineda

Purpose: To improve repeatability and reproducibility across acquisition parameters and reduce bias in quantitative susceptibility mapping (QSM) of the liver, through development of an optimized regularized reconstruction algorithm for…

Weak measurements of a superconducting qubit produce noisy voltage signals that are weakly correlated with the qubit state. To recover individual quantum trajectories from these noisy signals, traditional methods require slow qubit dynamics…

Whole-brain surface extraction is an essential topic in medical imaging systems as it provides neurosurgeons with a broader view of surgical planning and abnormality detection. To solve the problem confronted in current deep learning skull…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Heng Fang , Xi Yang , Taichi Kin , Takeo Igarashi

Deep learning-based image reconstruction approaches have demonstrated impressive empirical performance in many imaging modalities. These approaches usually require a large amount of high-quality paired training data, which is often not…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 Riccardo Barbano , Zeljko Kereta , Andreas Hauptmann , Simon R. Arridge , Bangti Jin

Introduction: Background field removal (BFR) is a critical step required for successful quantitative susceptibility mapping (QSM). However, eliminating the background field in brains containing significant susceptibility sources, such as…

Quantitative Methods · Quantitative Biology 2022-04-07 Xuanyu Zhu , Yang Gao , Feng Liu , Stuart Crozier , Hongfu Sun

In medical imaging, surface registration is extensively used for performing systematic comparisons between anatomical structures, with a prime example being the highly convoluted brain cortical surfaces. To obtain a meaningful registration,…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Yuchen Guo , Qiguang Chen , Gary P. T. Choi , Lok Ming Lui

We present Point2SSM, a novel unsupervised learning approach for constructing correspondence-based statistical shape models (SSMs) directly from raw point clouds. SSM is crucial in clinical research, enabling population-level analysis of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Jadie Adams , Shireen Elhabian

Quantitative phase imaging (QPI) is an emerging label-free technique that produces images containing morphological and dynamical information without contrast agents. Unfortunately, the phase is wrapped in most imaging system. Phase…

Image and Video Processing · Electrical Eng. & Systems 2021-09-01 Fangshu Yang , Thanh-an Pham , Nathalie Brandenberg , Matthias P. Lutolf , Jianwei Ma , Michael Unser

This paper proposes a novel self-supervised learning method, RELAX-MORE, for quantitative MRI (qMRI) reconstruction. The proposed method uses an optimization algorithm to unroll a model-based qMRI reconstruction into a deep learning…

Biological Physics · Physics 2023-07-26 Wanyu Bian , Albert Jang , Fang Liu

Multi-spectral quantitative phase imaging (MS-QPI) is a cutting-edge label-free technique to determine the morphological changes, refractive index variations and spectroscopic information of the specimens. The bottleneck to implement this…

Self-Attention Mechanism (SAM) is good at capturing the internal connections of features and greatly improves the performance of machine learning models, espeacially requiring efficient characterization and feature extraction of…

Quantum Physics · Physics 2023-08-08 Jinjing Shi , Ren-Xin Zhao , Wenxuan Wang , Shichao Zhang , Xuelong Li

Purpose Supervised deep learning in radiology suffers from notorious inherent limitations: 1) It requires large, hand-annotated data sets, 2) It is non-generalizable, and 3) It lacks explainability and intuition. We have recently proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph N Stember , Hrithwik Shalu