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While the uptake of data-driven approaches for materials science and chemistry is at an exciting, early stage, to realise the true potential of machine learning models for successful scientific discovery, they must have qualities beyond…

Materials Science · Physics 2022-06-28 Felipe Oviedo , Juan Lavista Ferres , Tonio Buonassisi , Keith Butler

Machine learning models that offer excellent predictive performance often lack the interpretability necessary to support integrated human machine decision-making. In clinical medicine and other high-risk settings, domain experts may be…

Machine Learning · Computer Science 2021-04-19 Zach Wood-Doughty , Isabel Cachola , Mark Dredze

In recent years, machine learning (ML) has become a key enabling technology for the sciences and industry. Especially through improvements in methodology, the availability of large databases and increased computational power, today's ML…

Artificial Intelligence · Computer Science 2019-09-27 Wojciech Samek , Klaus-Robert Müller

The interpretability of ML models is important, but it is not clear what it amounts to. So far, most philosophers have discussed the lack of interpretability of black-box models such as neural networks, and methods such as explainable AI…

Machine Learning · Computer Science 2024-01-05 Tim Räz

Model explainability has become an important problem in machine learning (ML) due to the increased effect that algorithmic predictions have on humans. Explanations can help users understand not only why ML models make certain predictions,…

Machine Learning · Computer Science 2022-09-13 Ana Lucic

Software analytics has been the subject of considerable recent attention but is yet to receive significant industry traction. One of the key reasons is that software practitioners are reluctant to trust predictions produced by the analytics…

Software Engineering · Computer Science 2018-02-05 Hoa Khanh Dam , Truyen Tran , Aditya Ghose

The last decade has seen huge progress in the development of advanced machine learning models; however, those models are powerless unless human users can interpret them. Here we show how the mind's construction of concepts and meaning can…

Machine Learning · Statistics 2016-07-04 Nick Condry

In this review, we examine the problem of designing interpretable and explainable machine learning models. Interpretability and explainability lie at the core of many machine learning and statistical applications in medicine, economics,…

Machine Learning · Computer Science 2023-03-02 Ričards Marcinkevičs , Julia E. Vogt

To design tools and data pipelines for explainable B2B machine learning (ML) systems, we need to recognize not only the immediate audience of such tools and data, but also (1) their organizational context and (2) secondary audiences. Our…

Human-Computer Interaction · Computer Science 2019-06-13 Kit Kuksenok

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

Artificial Intelligence · Computer Science 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

Machine Learning · Computer Science 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Model explainability is essential for the creation of trustworthy Machine Learning models in healthcare. An ideal explanation resembles the decision-making process of a domain expert and is expressed using concepts or terminology that is…

Machine Learning · Computer Science 2021-07-14 Sumedha Singla , Stephen Wallace , Sofia Triantafillou , Kayhan Batmanghelich

Machine Learning explainability techniques have been proposed as a means of `explaining' or interrogating a model in order to understand why a particular decision or prediction has been made. Such an ability is especially important at a…

Machine Learning · Statistics 2022-02-28 Matthew J. Vowels

During a research project in which we developed a machine learning (ML) driven visualization system for non-ML experts, we reflected on interpretability research in ML, computer-supported collaborative work and human-computer interaction.…

Human-Computer Interaction · Computer Science 2022-01-19 Jesse Josua Benjamin , Christoph Kinkeldey , Claudia Müller-Birn , Tim Korjakow , Eva-Maria Herbst

A task of interest in machine learning (ML) is that of ascribing explanations to the predictions made by ML models. Furthermore, in domains deemed high risk, the rigor of explanations is paramount. Indeed, incorrect explanations can and…

Artificial Intelligence · Computer Science 2025-07-11 Mohamed Siala , Jordi Planes , Joao Marques-Silva

As machine learning systems become ubiquitous, there has been a surge of interest in interpretable machine learning: systems that provide explanation for their outputs. These explanations are often used to qualitatively assess other…

Machine Learning · Statistics 2017-03-06 Finale Doshi-Velez , Been Kim

Recent success in Artificial Intelligence (AI) and Machine Learning (ML) allow problem solving automatically without any human intervention. Autonomous approaches can be very convenient. However, in certain domains, e.g., in the medical…

Artificial Intelligence · Computer Science 2021-03-03 Andreas Holzinger , André Carrington , Heimo Müller

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

Methodology · Statistics 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

As machine learning is increasingly deployed in high-stakes contexts affecting people's livelihoods, there have been growing calls to open the black box and to make machine learning algorithms more explainable. Providing useful explanations…

Computers and Society · Computer Science 2020-07-13 Umang Bhatt , McKane Andrus , Adrian Weller , Alice Xiang