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Inferring brain connectivity and structure \textit{in-vivo} requires accurate estimation of the orientation distribution function (ODF), which encodes key local tissue properties. However, estimating the ODF from diffusion MRI (dMRI)…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 William Consagra , Lipeng Ning , Yogesh Rathi

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…

Neurons and Cognition · Quantitative Biology 2019-04-15 Ye Wu , Yoonmi Hong , Yuanjing Feng , Dinggang Shen , Pew-Thian Yap

The Orientation Distribution Function (ODF) characterizes key brain microstructural properties and plays an important role in understanding brain structural connectivity. Recent works introduced Implicit Neural Representation (INR) based…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Mohammed Munzer Dwedari , William Consagra , Philip Müller , Özgün Turgut , Daniel Rueckert , Yogesh Rathi

Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Lei Xie , Qingrun Zeng , Huajun Zhou , Guoqiang Xie , Mingchu Li , Jiahao Huang , Jianan Cui , Hao Chen , Yuanjing Feng

A novel approach is presented for group statistical analysis of diffusion weighted MRI datasets through voxelwise Orientation Distribution Functions (ODF). Recent advances in MRI acquisition make it possible to use high quality diffusion…

Medical Physics · Physics 2019-05-13 Steven H. Baete , Jingyun Chen , Ying-Chia Lin , Xiuyuan Wang , Ricardo Otazo , Fernando E. Boada

Due to recent technological advances, large brain imaging data sets can now be collected. Such data are highly complex so extraction of meaningful information from them remains challenging. Thus, there is an urgent need for statistical…

Applications · Statistics 2021-06-30 Seungyong Hwang , Thomas C. M. Lee , Debashis Paul , Jie Peng

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Jakob Wasserthal , Peter F. Neher , Klaus H. Maier-Hein

White matter structures composed of myelinated axons in the living human brain are primarily studied by diffusion-weighted MRI (dMRI). These long-range projections are typically characterized in a two-step process: dMRI is used to estimate…

Neurons and Cognition · Quantitative Biology 2017-10-09 Matthew Cieslak , Tegan Brennan , Wendy Meiring , Lukas J. Volz , Clint Greene , Alexander Asturias , Subhash Suri , Scott T. Grafton

Diffusion magnetic resonance imaging (dMRI) is currently the only tool for noninvasively imaging the brain's white matter tracts. The fiber orientation (FO) is a key feature computed from dMRI for fiber tract reconstruction. Because the…

Computer Vision and Pattern Recognition · Computer Science 2017-05-22 Chuyang Ye , Jerry L. Prince

We present a novel method for estimation of the fiber orientation distribution (FOD) function based on diffusion-weighted Magnetic Resonance Imaging (D-MRI) data. We formulate the problem of FOD estimation as a regression problem through…

Applications · Statistics 2016-12-23 Hao Yan , Owen Carmichael , Debashis Paul , Jie Peng

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in micro-structure imaging and…

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial method for white matter (WM) parcellation to enable analysis of brains structural connectivity in health and disease. Current fiber clustering strategies primarily use…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Bocheng Guo , Jin Wang , Yijie Li , Junyi Wang , Mingyu Gao , Puming Feng , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Jakob Wasserthal , Peter Neher , Dusan Hirjak , Klaus H. Maier-Hein

With the widespread application of location-based services, fingerprint-based localization has demonstrated advantages in environments with complex signal propagation. Deep learning has significantly improved the efficiency of both offline…

Information Theory · Computer Science 2026-05-27 Yu Zhao , Zhenzhou Jin , Jinke Tang , Li You , Chen Sun , Xiang-Gen Xia , Xiqi Gao

Learning new representations of 3D point clouds is an active research area in 3D vision, as the order-invariant point cloud structure still presents challenges to the design of neural network architectures. Recent works explored learning…

Computer Vision and Pattern Recognition · Computer Science 2022-07-18 Yusuf H. Sahin , Alican Mertan , Gozde Unal

Ultra-low-field (ULF) MRI is emerging as an alternative modality to high-field (HF) MRI due to its lower cost, minimal siting requirements, portability, and enhanced accessibility factors that enable large-scale deployment. Although ULF-MRI…

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