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We study three fundamental statistical-learning problems: distribution estimation, property estimation, and property testing. We establish the profile maximum likelihood (PML) estimator as the first unified sample-optimal approach to a wide…

Machine Learning · Statistics 2019-07-12 Yi Hao , Alon Orlitsky

This paper presents a tractable sufficient condition for the consistency of maximum likelihood estimators (MLEs) in partially observed diffusion models, stated in terms of stationary distribution of the associated fully observed diffusion,…

Statistics Theory · Mathematics 2024-12-10 Sergey Nadtochiy , Yuan Yin

We study the population genetics of two neutral alleles under reversible mutation in the \Lambda-processes, a population model that features a skewed offspring distribution. We describe the shape of the equilibrium allele frequency…

Populations and Evolution · Quantitative Biology 2013-06-21 Ricky Der , Joshua B. Plotkin

In multiple change-point problems, different data segments often follow different distributions, for which the changes may occur in the mean, scale or the entire distribution from one segment to another. Without the need to know the number…

Statistics Theory · Mathematics 2014-05-29 Changliang Zou , Guosheng Yin , Long Feng , Zhaojun Wang

In Bayesian hypothesis testing and model selection, prior distributions must be chosen carefully. For example, setting arbitrarily large prior scales for location parameters, which is common practice in estimation problems, can lead to…

Statistics Theory · Mathematics 2019-11-25 Víctor Peña , James O. Berger

The pattern maximum likelihood (PML) estimate, introduced by Orlitsky et al., is an estimate of the multiset of probabilities in an unknown probability distribution $\mathbf{p}$, the estimate being obtained from $n$ i.i.d. samples drawn…

Discrete Mathematics · Computer Science 2015-06-03 Chun Lam Chan , Winston Fernandes , Navin Kashyap , Manjunath Krishnapur

We propose a Bayesian test of normality for univariate or multivariate data against alternative nonparametric models characterized by Dirichlet process mixture distributions. The alternative models are based on the principles of embedding…

Statistics Theory · Mathematics 2023-04-12 Surya T. Tokdar , Ryan Martin

In the Admixture Model, the probability of an individual having a certain number of alleles at a specific marker depends on the allele frequencies in $K$ ancestral populations and the fraction of the individual's genome originating from…

Applications · Statistics 2025-07-29 Carola Sophia Heinzel

In this article, we introduce a two-way factor model for a high-dimensional data matrix and study the properties of the maximum likelihood estimation (MLE). The proposed model assumes separable effects of row and column attributes and…

Methodology · Statistics 2021-03-17 Gao Zhigen , Yuan Chaofeng , Jing Bingyi , Huang Wei , Guo Jianhua

The asymptotic variance of the maximum likelihood estimate is proved to decrease when the maximization is restricted to a subspace that contains the true parameter value. Maximum likelihood estimation allows a systematic fitting of…

Statistics Theory · Mathematics 2018-01-31 Marie Turčičová , Jan Mandel , Kryštof Eben

Benchmark dose (BMD; a dose associated with a specified change in response) is used to determine the point of departure for the acceptable daily intake of substances for humans. Multiple dose-response relationship models are considered in…

Computation · Statistics 2025-05-13 Sota Minewaki , Tomohiro Ohigashi , Takashi Sozu

The Luria-Delbr\"uck distribution is a classical model of mutations in cell kinetics. It is obtained as a limit when the probability of mutation tends to zero and the number of divisions to infinity. It can be interpreted as a compound…

Applications · Statistics 2013-09-11 Agnès Hamon , Bernard Ycart

A two-stage adaptive optimal design is an attractive option for increasing the efficiency of clinical trials. In these designs, based on interim data, the locally optimal dose is chosen for further exploration, which induces dependencies…

Methodology · Statistics 2019-05-24 Zhantao Lin , Nancy Flournoy , William F. Rosenberger

Block maxima methods constitute a fundamental part of the statistical toolbox in extreme value analysis. However, most of the corresponding theory is derived under the simplifying assumption that block maxima are independent observations…

Statistics Theory · Mathematics 2019-07-24 Nan Zou , Stanislav Volgushev , Axel Bücher

This article proposes a mixture modeling approach to estimating cluster-wise conditional distributions in clustered (grouped) data. We adapt the mixture-of-experts model to the latent distributions, and propose a model in which each…

Methodology · Statistics 2019-09-10 Shonosuke Sugasawa , Genya Kobayashi , Yuki Kawakubo

We propose sequential Monte Carlo based algorithms for maximum likelihood estimation of the static parameters in hidden Markov models with an intractable likelihood using ideas from approximate Bayesian computation. The static parameter…

Computation · Statistics 2013-11-19 Sinan Yildirim , Sumeetpal Singh , Thomas Dean , Ajay Jasra

In this article we propose novel Bayesian nonparametric methods using Dirichlet Process Mixture (DPM) models for detecting pairwise dependence between random variables while accounting for uncertainty in the form of the underlying…

Methodology · Statistics 2016-04-28 Sarah Filippi , Chris C. Holmes , Luis E. Nieto-Barajas

The maximum likelihood estimator (MLE) is pivotal in statistical inference, yet its application is often hindered by the absence of closed-form solutions for many models. This poses challenges in real-time computation scenarios,…

Methodology · Statistics 2025-04-16 Pedro L. Ramos , Eduardo Ramos , Francisco A. Rodrigues , Francisco Louzada

In this paper, we consider a linear regression model with AR(p) error terms with the assumption that the error terms have a t distribution as a heavy tailed alternative to the normal distribution. We obtain the estimators for the model…

Computation · Statistics 2017-10-13 Yetkin Tuaç , Yeşim Güney Birdal Şenoğlu , Olcay Arslan

The H\"usler-Reiss distribution describes the limit of the pointwise maxima of a bivariate normal distribution. This distribution is defined by a single parameter, $\lambda$. We provide asymptotic theory for maximum likelihood estimation of…

Statistics Theory · Mathematics 2024-10-16 Hank Flury , Jan Hannig , Richard Smith