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We study the evolutionary robustness of strategies in infinitely repeated prisoners' dilemma games in which players make mistakes with a small probability and are patient. The evolutionary process we consider is given by the replicator…

Dynamical Systems · Mathematics 2020-08-03 Pedro Dal Bó , Enrique R. Pujals

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

Evolutionary and ecosystem dynamics are often treated as different processes --operating at separate timescales-- even if evidence reveals that rapid evolutionary changes can feed back into ecological interactions. A recent long-term field…

Populations and Evolution · Quantitative Biology 2018-10-04 Paula Villa Martín , Jorge Hidalgo , Rafael Rubio de Casas , Miguel A. Muñoz

Ecological systems comprise an astonishing diversity of species that cooperate or compete with each other forming complex mutual dependencies. The minimum requirements to maintain a large species diversity on long time scales are in general…

Populations and Evolution · Quantitative Biology 2012-09-10 Joachim Mathiesen , Namiko Mitarai , Kim Sneppen , Ala Trusina

The aim of this paper is two-fold. First, we propose a new computational method to investigate the particularities of evolution. Second, we apply this method to a model of gene regulatory networks (GRNs) and explore the evolution of…

Molecular Networks · Quantitative Biology 2022-01-21 Tadamune Kaneko , Macoto Kikuchi

Antigenic escape constitutes the main mechanism allowing rapidly evolving viruses to achieve endemicity. Beyond granting immune escape, empirical evidence also suggests that mutations of viruses might increase their inter-host…

Populations and Evolution · Quantitative Biology 2025-11-20 David Soriano-Paños

The tendency of repeating past choices more often than expected from the history of outcomes has been repeatedly empirically observed in reinforcement learning experiments. It can be explained by at least two computational processes:…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Isabelle Hoxha , Leo Sperber , Stefano Palminteri

Successful adaptation helped the emergence of complexity. Alternating plastic- and rigid-like states were recurrently considered to play a role in adaptive processes. However, this extensive knowledge remained fragmented. In this paper I…

Molecular Networks · Quantitative Biology 2015-11-09 Peter Csermely

The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key…

Populations and Evolution · Quantitative Biology 2013-04-16 Bjørn Østman

Viruses evolve in the background of host immune systems that exert selective pressure and drive viral evolutionary trajectories. This interaction leads to different evolutionary patterns in antigenic space. Examples observed in nature…

Populations and Evolution · Quantitative Biology 2020-11-20 Jacopo Marchi , Michael Lässig , Thierry Mora , Aleksandra M. Walczak

Biological organisms are adaptive, able to function in unpredictably changing environments. Drawing on recent nonequilibrium physics, we show that in adaptation, fitness has two components parameterized by observable coordinates: a static…

Statistical Mechanics · Physics 2026-02-19 Ying-Jen Yang , Charles D. Kocher , Ken A. Dill

Random walks on multidimensional nonlinear landscapes are of interest in many areas of science and engineering. In particular, properties of adaptive trajectories on fitness landscapes determine population fates and thus play a central role…

Populations and Evolution · Quantitative Biology 2014-10-08 Michael Manhart , Alexandre V. Morozov

Although there are some real world applications where the use of variable length representation (VLR) in Evolutionary Algorithm is natural and suitable, an academic framework is lacking for such representations. In this work we propose a…

Neural and Evolutionary Computing · Computer Science 2007-07-05 Michael Defoin Platel , Sebastien Verel , Manuel Clergue , Philippe Collard

We explore the connection between migration patterns and emergent behaviors of evolving populations in spatially heterogeneous environments. Despite extensive studies in ecologically and medically important systems, a unifying framework…

Populations and Evolution · Quantitative Biology 2024-01-10 Casey O. Barkan , Shenshen Wang

Understanding the emergence and sustainability of cooperation is a fundamental problem in evolutionary biology and is frequently studied by the framework of evolutionary game theory. A very powerful mechanism to promote cooperation is…

Computer Science and Game Theory · Computer Science 2015-05-27 M. Brede

One essential ingredient of evolutionary theory is the concept of fitness as a measure for a species' success in its living conditions. Here, we quantify the effect of environmental fluctuations onto fitness by analytical calculations on a…

Populations and Evolution · Quantitative Biology 2015-05-19 Anna Melbinger , Massimo Vergassola

Protein fitness landscapes frequently exhibit epistasis, where the effect of a mutation depends on the genetic context in which it occurs, i.e., the rest of the protein sequence. Epistasis increases landscape complexity, often resulting in…

Populations and Evolution · Quantitative Biology 2026-03-19 Anna Ottavia Schulte , Samar Alqatari , Saverio Rossi , Francesco Zamponi

A variety of genome transformations can occur as a microbial population adapts to a large environmental change. In particular, genomic surveys indicate that, following the transition to an obligate, host-dependent symbiont, the density of…

Populations and Evolution · Quantitative Biology 2015-03-17 Nicholas Chia , Nigel Goldenfeld

The advancement of general-purpose intelligent agents is intrinsically linked to the environments in which they are trained. While scaling models and datasets has yielded remarkable capabilities, scaling the complexity, diversity, and…

Machine Learning · Computer Science 2025-11-05 Brennen Hill

Biochemical and regulatory interactions central to biological networks are expected to cause extensive genetic interactions or epistasis affecting the heritability of complex traits and the distribution of genotypes in populations. However,…

Populations and Evolution · Quantitative Biology 2009-12-15 Richard A. Neher , Boris I. Shraiman