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CT perfusion (CTP) has been used to triage ischemic stroke patients in the early stage, because of its speed, availability, and lack of contraindications. Perfusion parameters including cerebral blood volume (CBV), cerebral blood flow…

Ischemic stroke lesion segmentation from Computed Tomography Perfusion (CTP) images is important for accurate diagnosis of stroke in acute care units. However, it is challenged by low image contrast and resolution of the perfusion parameter…

Stroke is among the top three causes of death worldwide, and accurate identification of ischemic stroke lesion boundaries from imaging is critical for diagnosis and treatment. The main imaging modalities used include magnetic resonance…

Purpose: In this study we investigate whether a Convolutional Neural Network (CNN) can generate clinically relevant parametric maps from CT perfusion data in a clinical setting of patients with acute ischemic stroke. Methods: Training of…

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

Stroke is the second most common cause of death in developed countries, where rapid clinical intervention can have a major impact on a patient's life. To perform the revascularization procedure, the decision making of physicians considers…

Computed tomography (CT) is essential for treatment and diagnostics; In case CT are missing or otherwise difficult to obtain, methods for generating synthetic CT (sCT) images from magnetic resonance imaging (MRI) images are sought after.…

Focal deficits in ischaemic stroke result from impaired perfusion downstream of a critical vascular occlusion. While parenchymal lesions are traditionally used to predict clinical deficits, the underlying pattern of disrupted perfusion…

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

CT Perfusion (CTP) imaging has gained importance in the diagnosis of acute stroke. Conventional perfusion analysis performs a deconvolution of the measurements and thresholds the perfusion parameters to determine the tissue status. We…

Magnetic Resonance (MR) Imaging and Computed Tomography (CT) are the primary diagnostic imaging modalities quite frequently used for surgical planning and analysis. A general problem with medical imaging is that the acquisition process is…

Deep learning has a great potential to alleviate diagnosis and prognosis for various clinical procedures. However, the lack of a sufficient number of medical images is the most common obstacle in conducting image-based analysis using deep…

In this work, we present a novel convolutional neural net- work based method for perfusion map generation in dynamic suscepti- bility contrast-enhanced perfusion imaging. The proposed architecture is trained end-to-end and solely relies on…

Precise and fast prediction methods for ischemic areas comprised of dead tissue, core, and salvageable tissue, penumbra, in acute ischemic stroke (AIS) patients are of significant clinical interest. They play an essential role in improving…

Perfusion imaging is extensively utilized to assess hemodynamic status and tissue perfusion in various organs. Computed tomography perfusion (CTP) imaging plays a key role in the early assessment and planning of stroke treatment. While CTP…

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…

Accurate segmentation of ischemic stroke lesions from diffusion magnetic resonance imaging (MRI) is essential for clinical decision-making and outcome assessment. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC)…

Purpose: Multi-expert deep learning training methods to automatically quantify ischemic brain tissue on Non-Contrast CT Materials and Methods: The data set consisted of 260 Non-Contrast CTs from 233 patients of acute ischemic stroke…

Data augmentation can effectively resolve a scarcity of images when training machine-learning algorithms. It can make them more robust to unseen images. We present a lesion conditional Generative Adversarial Network LcGAN to generate…

The CT perfusion (CTP) is a medical exam for measuring the passage of a bolus of contrast solution through the brain on a pixel-by-pixel basis. The objective is to draw "perfusion maps" (namely cerebral blood volume, cerebral blood flow and…