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Stroke is a leading cause of disability and death. Effective treatment decisions require early and informative vascular imaging. 4D perfusion imaging is ideal but rarely available within the first hour after stroke, whereas plain CT and CTA…

Magnetic resonance image (MRI) reconstruction is a severely ill-posed linear inverse task demanding time and resource intensive computations that can substantially trade off {\it accuracy} for {\it speed} in real-time imaging. In addition,…

Ischemic stroke occurs through a blockage of clogged blood vessels supplying blood to the brain. Segmentation of the stroke lesion is vital to improve diagnosis, outcome assessment and treatment planning. In this work, we propose a…

CT perfusion imaging (CTP) is used in the diagnostic workup of acute ischemic stroke (AIS). CTP may be performed within the angio suite using flat detector CT (FDCT) to help reduce patient management time. In order to significantly improve…

Automated medical image analysis has a significant value in diagnosis and treatment of lesions. Brain tumors segmentation has a special importance and difficulty due to the difference in appearances and shapes of the different tumor regions…

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

The patient with ischemic stroke can benefit most from the earliest possible definitive diagnosis. While the high quality medical resources are quite scarce across the globe, an automated diagnostic tool is expected in analyzing the…

Ischemic stroke is a time-critical medical emergency where rapid diagnosis is essential for improving patient outcomes. Non-contrast computed tomography (NCCT) serves as the frontline imaging tool, yet it often fails to reveal the subtle…

In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net…

Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…

Deep learning (DL) models in medical imaging face challenges in generalizability and robustness due to variations in image acquisition parameters (IAP). In this work, we introduce a novel method using conditional denoising diffusion…

Mapping from functional connectivity (FC) to structural connectivity (SC) can facilitate multimodal brain network fusion and discover potential biomarkers for clinical implications. However, it is challenging to directly bridge the reliable…

MR-only radiotherapy treatment planning requires accurate MR-to-CT synthesis. Current deep learning methods for MR-to-CT synthesis depend on pairwise aligned MR and CT training images of the same patient. However, misalignment between…

Segmenting stroke lesions from T1-weighted MR images is of great value for large-scale stroke rehabilitation neuroimaging analyses. Nevertheless, there are great challenges with this task, such as large range of stroke lesion scales and the…

In this paper, we describe how to apply image-to-image translation techniques to medical blood smear data to generate new data samples and meaningfully increase small datasets. Specifically, given the segmentation mask of the microscopy…

In vivo cardiac diffusion tensor imaging (cDTI) is a promising Magnetic Resonance Imaging (MRI) technique for evaluating the micro-structure of myocardial tissue in the living heart, providing insights into cardiac function and enabling the…

MRI and CT are most widely used medical imaging modalities. It is often necessary to acquire multi-modality images for diagnosis and treatment such as radiotherapy planning. However, multi-modality imaging is not only costly but also…

End-to-end deep learning improves breast cancer classification on diffusion-weighted MR images (DWI) using a convolutional neural network (CNN) architecture. A limitation of CNN as opposed to previous model-based approaches is the…

Acute ischemic stroke (AIS) requires time-critical management, with hours of delayed intervention leading to an irreversible disability of the patient. Since diffusion weighted imaging (DWI) using the magnetic resonance image (MRI) plays a…

Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure…