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Quantum sensing exploits fundamental features of quantum mechanics and quantum control to realise sensing devices with potential applications in a broad range of scientific fields ranging from basic science to applied technology. The…

Mesoscale and Nanoscale Physics · Physics 2019-11-13 Wanlu Song , Tianyi Du , Haibin Liu , Martin B. Plenio , Jianming Cai

The nitrogen-vacancy center in diamond has been broadly applied in quantum sensing since it is sensitive to different physical quantities. Meanwhile, it is difficult to isolate disturbances from unwanted physical quantities in practical…

Optical sensing is one of the key-enablers of modern diagnostics. Especially label-free imaging modalities hold great promise as they eliminate labeling procedures prior to analysis. However, scattering signals of nanometric particles scale…

Optics · Physics 2021-02-03 Unai Ortiz-Orruño , Ala Jo , Hakho Lee , Niek F. van Hulst , Matz Liebel

Label-free imaging of rapidly moving, sub-diffraction sized structures has important applications in both biology and material science, as it removes the limitations associated with fluorescence tagging. However, unlabeled nanoscale…

Optical biosensors are indispensable in medical and environmental diagnostics, yet existing approaches are fundamentally limited in their sensitivity due to ensemble-averaged measurements. Digital biosensing has emerged as a promising…

This review provides a critical overview of current developments on nanoelectronic biochemical sensors based on graphene. Composed of a single layer of conjugated carbon atoms, graphene has outstanding high carrier mobility and low…

Materials Science · Physics 2020-12-14 Xiaoyan Zhang , Qiushi Jing , Shen Ao , Grégory F. Schneider , Dmitry Kireev , Zhengjun Zhang , Wangyang Fu

Using the ultraviolet autofluorescence of tryptophan aminoacids offers fascinating perspectives to study single proteins without the drawbacks of fluorescence labelling. However, the low autofluorescence signals have so far limited the UV…

Detection and characterization of individual nano-scale particles, virions, and pathogens are of paramount importance to human health, homeland security, diagnostic and environmental monitoring[1]. There is a strong demand for…

Optics · Physics 2011-07-06 Lina He , Sahin Kaya Ozdemir , Jiangang Zhu , Woosung Kim , Lan Yang

Quantum control of atoms at ultrashort distances from surfaces would open a new paradigm in quantum optics and offer a novel tool for the investigation of near-surface physics. Here, we investigate the motional states of atoms that are…

Quantum Physics · Physics 2021-04-23 Daniel Hümmer , Oriol Romero-Isart , Arno Rauschenbeutel , Philipp Schneeweiss

Quantum noise sets a fundamental limit to the sensitivity of high-precision measurements. Suppressing it can be achieved by using non-classical states and quantum filters, which modify both the noise and signal response. We find a novel…

Quantum Physics · Physics 2021-03-09 Joe Bentley , Hendra Nurdin , Yanbei Chen , Haixing Miao

Recent advancements in nanotechnology have led to the development of surface-enhanced Raman spectroscopy (SERS) based rapid and low-cost technologies for ultra-sensitive label-free detection and identification of molecular analytes. Herein,…

High-efficiency optical detectors that can determine the number of photons in a pulse of monochromatic light have applications in a variety of physics studies, including post-selection-based entanglement protocols for linear optics quantum…

Quantum Physics · Physics 2009-11-11 Danna Rosenberg , Adriana E. Lita , Aaron J. Miller , Sae Woo Nam

More than twenty years ago, scientists succeeded in pushing the limits of optical detection to single molecules using fluorescence. This breakthrough has revolutionized biophysical measurements, but restrictions in photophysics and labeling…

Biological Physics · Physics 2015-06-17 Marek Piliarik , Vahid Sandoghdar

Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…

Interferometric-based microscopies stand as powerful label-free approaches for monitoring and characterising chemical reactions and heterogeneous nanoparticle systems in real time with single particle sensitivity. Nevertheless, coherent…

Miniaturized, low-cost wavelength detectors are gaining enormous interest as we step into the new age of photonics. Incompatibility with integrated circuits or complex fabrication requirement in most of the conventionally used filters…

The ultimate detection limit of optical biosensors is often limited by various noise sources, including those introduced by the optical measurement setup. While sophisticated modifications to instrumentation may reduce noise, a simpler…

Signal Processing · Electrical Eng. & Systems 2021-09-07 Simon J. Ward , Rabeb Layouni , Sofia Arshavsky-Graham , Ester Segal , Sharon M. Weiss

This paper studies quantum limits to dynamical sensors in the presence of decoherence. A modified purification approach is used to obtain tighter quantum detection and estimation error bounds for optical phase sensing and optomechanical…

Quantum Physics · Physics 2013-07-04 Mankei Tsang

Biosensors are essential tools which have been traditionally used to monitor environmental pollution, detect the presence of toxic elements and biohazardous bacteria or virus in organic matter and biomolecules for clinical diagnostics. In…

Chemical Physics · Physics 2021-01-08 Aishwaryadev Banerjee , Swagata Maity , Carlos H. Mastrangelo

In the biochemical sensing field, a fervent research activity related to the development of real time, low cost, compact and high throughput devices for the detection and characterization of natural or synthetic nanoparticles NPs actually…

Optics · Physics 2014-01-13 Clarissa Martina Campanella