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Exploring methods and techniques of machine learning (ML) to address specific challenges in various fields is essential. In this work, we tackle a problem in the domain of Cheminformatics; that is, providing a suitable solution to aid in…

Biomolecules · Quantitative Biology 2024-01-03 Do Hoang Tu , Tran Van Lang , Pham Cong Xuyen , Le Mau Long

Machine learning (ML) can be used to construct surrogate models for the fast prediction of a property of interest. ML can thus be applied to chemical projects, where the usual experimentation or calculation techniques can take hours or days…

We show how a quantum computer can be employed to elucidate reaction mechanisms in complex chemical systems, using the open problem of biological nitrogen fixation in nitrogenase as an example. We discuss how quantum computers can augment…

Quantum Physics · Physics 2017-08-14 Markus Reiher , Nathan Wiebe , Krysta M Svore , Dave Wecker , Matthias Troyer

For the investigation of chemical reaction networks, the identification of all relevant intermediates and elementary reactions is mandatory. Many algorithmic approaches exist that perform explorations efficiently and automatedly. These…

Chemical Physics · Physics 2019-05-24 Gregor N. Simm , Alain C. Vaucher , Markus Reiher

We present a novel method for identifying a biochemical reaction network based on multiple sets of estimated reaction rates in the corresponding reaction rate equations arriving from various (possibly different) experiments. The current…

Applications · Statistics 2008-10-06 Gheorghe Craciun , Casian Pantea , Grzegorz A. Rempala

Automatic judgment prediction aims to predict the judicial results based on case materials. It has been studied for several decades mainly by lawyers and judges, considered as a novel and prospective application of artificial intelligence…

Artificial Intelligence · Computer Science 2018-09-19 Shangbang Long , Cunchao Tu , Zhiyuan Liu , Maosong Sun

In this paper, I describe several approaches to automatic or semi-automatic development of symbolic rules for grammar checkers from the information contained in corpora. The rules obtained this way are an important addition to…

Computation and Language · Computer Science 2012-11-30 Marcin Miłkowski

The yield of a chemical reaction quantifies the percentage of the target product formed in relation to the reactants consumed during the chemical reaction. Accurate yield prediction can guide chemists toward selecting high-yield reactions…

Machine Learning · Computer Science 2025-02-06 Yihong Ma , Xiaobao Huang , Bozhao Nan , Nuno Moniz , Xiangliang Zhang , Olaf Wiest , Nitesh V. Chawla

While the uptake of data-driven approaches for materials science and chemistry is at an exciting, early stage, to realise the true potential of machine learning models for successful scientific discovery, they must have qualities beyond…

Materials Science · Physics 2022-06-28 Felipe Oviedo , Juan Lavista Ferres , Tonio Buonassisi , Keith Butler

Uncertainty quantification enables users to assess the reliability of responses generated by large language models (LLMs). We present a novel Question Rephrasing technique to evaluate the input uncertainty of LLMs, which refers to the…

Computation and Language · Computer Science 2024-08-08 Zizhang Chen , Pengyu Hong , Sandeep Madireddy

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

Quantum chemical studies of reactivity involve calculations on a large number of molecular structures and comparison of their energies. Already the set-up of these calculations limits the scope of the results that one will obtain, because…

Computational Physics · Physics 2016-08-23 Alain C. Vaucher , Markus Reiher

For several decades, chemical knowledge has been published in written text, and there have been many attempts to make it accessible, for example, by transforming such natural language text to a structured format. Although the discovered…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Sanghyun Yoo , Ohyun Kwon , Hoshik Lee

Autonomous computations that rely on automated reaction network elucidation algorithms may pave the way to make computational catalysis on a par with experimental research in the field. Several advantages of this approach are key to…

Materials Science · Physics 2022-03-18 Miguel Steiner , Markus Reiher

This systematic review focuses on analyzing the use of machine learning techniques for identifying and quantifying analytes in various electrochemical applications, presenting the available applications in the literature. Machine learning…

It is standard in chemistry to represent a sequence of reactions by a single overall reaction, often called a complex reaction in contrast to an elementary reaction. Photosynthesis $6 \text{CO}_2+6 \text{H}_2\text{O} \to \…

Combinatorics · Mathematics 2022-03-28 Linard Hoessly , Carsten Wiuf , Panqiu Xia

The ability to generate, organize, analyze, understand and leverage data for sound decision making is a central activity of chemical engineers. Chemical engineers are responsible for the safe, profitable and environmentally friendly…

Applications · Statistics 2022-08-08 Suparna Samavedham , S. Lakshminarayanan

Based on limited observations, machine learning discerns a dependence which is expected to hold in the future. What makes it possible? Statistical learning theory imagines indefinitely increasing training sample to justify its approach. In…

Machine Learning · Computer Science 2025-01-06 Marina Sapir

Chemical information extraction is to convert chemical knowledge in text into true chemical database, which is a text processing task heavily relying on chemical compound name identification and standardization. Once a systematic name for a…

Computation and Language · Computer Science 2019-01-23 Junlang Zhan , Hai Zhao

Simulating chemical systems is highly sought after and computationally challenging, as the number of degrees of freedom increases exponentially with the size of the system. Quantum computers have been proposed as a computational means to…

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