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Biomedical datasets are often constrained by stringent privacy requirements and frequently suffer from severe class imbalance. These two aspects hinder the development of accurate machine learning models. While generative AI offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Jan Carreras Boada , Rao Muhammad Umer , Carsten Marr

We demonstrate novel instrumentation for spontaneous Raman spectroscopy in biofluids, enabling development of a portable, automated, reliable diagnostics technique requiring minimal operator expertise to quantify disease markers. Label-free…

Biological Physics · Physics 2021-05-27 Emily E. Storey , Duxuan Wu , Amr S. Helmy

The rapid development of deep learning has made a great progress in image segmentation, one of the fundamental tasks of computer vision. However, the current segmentation algorithms mostly rely on the availability of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-02-16 Wei Shen , Zelin Peng , Xuehui Wang , Huayu Wang , Jiazhong Cen , Dongsheng Jiang , Lingxi Xie , Xiaokang Yang , Qi Tian

The rapid advancement of deep learning (DL) has transformed healthcare, particularly in cancer detection and diagnosis. DL surpasses traditional machine learning and human accuracy, making it a critical tool for identifying diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Yassine Habchi , Hamza Kheddar , Yassine Himeur , Adel Belouchrani , Erchin Serpedin , Fouad Khelifi , Muhammad E. H. Chowdhury

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

We show how the ability to slow down, amplify, and capture fast transient events can produce high-throughput real-time instruments ranging from digitizers to imaging flow cytometers for detection of rare diseased cells in blood.

Instrumentation and Detectors · Physics 2011-06-29 Bahram Jalali , Keisuke Goda , Ali Fard , Sang Hyup Kim

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to the overproduction of immature white blood cells that encroach upon the space required for the generation of healthy blood cells.Leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Md. Abu Ahnaf Mollick , Md. Mahfujur Rahman , D. M. Asadujjaman , Abdullah Tamim , Nosin Anjum Dristi , Md. Takbir Hossen

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

Artificial Intelligence · Computer Science 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

Real-time tool segmentation from endoscopic videos is an essential part of many computer-assisted robotic surgical systems and of critical importance in robotic surgical data science. We propose two novel deep learning architectures for…

Time stretch instruments have been exceptionally successful in discovering single-shot ultrafast phenomena such as optical rogue waves and have led to record-speed microscopy, spectroscopy, lidar, etc. These instruments encode the ultrafast…

Optics · Physics 2023-04-06 Tingyi Zhou , Bahram Jalali

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Saban Ozturk , Tolga Cukur

Image classification systems recently made a giant leap with the advancement of deep neural networks. However, these systems require an excessive amount of labeled data to be adequately trained. Gathering a correctly annotated dataset is…

Machine Learning · Computer Science 2021-01-19 Görkem Algan , Ilkay Ulusoy

This work presents an optical neuromorphic imaging and processing cytometry system that integrates an excitable VCSEL-based time-delayed (TD) extreme learning machine with an event-based 2D camera. The proposed system is designed for the…

Optics · Physics 2025-05-20 M. Skontranis , G. Moustakas , A. Bogris , C. Mesaritakis

The accurate classification of white blood cells and related blood components is crucial for medical diagnoses. While traditional manual examinations and automated hematology analyzers have been widely used, they are often slow and prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alexander Kim , Ryan Kim

State-of-the-art deep learning systems rely on iterative distributed training to tackle the increasing complexity of models and input data. The iteration time in these communication-heavy systems depends on the computation time,…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-05 Sayed Hadi Hashemi , Sangeetha Abdu Jyothi , Roy H. Campbell

Nowadays, cardiac diagnosis largely depends on left ventricular function assessment. With the help of the segmentation deep learning model, the assessment of the left ventricle becomes more accessible and accurate. However, deep learning…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Hang Duong Thi Thuy , Tuan Nguyen Minh , Phi Nguyen Van , Long Tran Quoc

In multi-label classification, the main focus has been to develop ways of learning the underlying dependencies between labels, and to take advantage of this at classification time. Developing better feature-space representations has been…

Machine Learning · Computer Science 2015-02-23 Jesse Read , Fernando Perez-Cruz

Ultrasound imaging is challenging to interpret due to non-uniform intensities, low contrast, and inherent artifacts, necessitating extensive training for non-specialists. Advanced representation with clear tissue structure separation could…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Oleksandra Tmenova , Yordanka Velikova , Mahdi Saleh , Nassir Navab

Although deep learning-based computer-aided diagnosis systems have recently achieved expert-level performance, developing a robust deep learning model requires large, high-quality data with manual annotation, which is expensive to obtain.…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Sangjoon Park , Gwanghyun Kim , Yujin Oh , Joon Beom Seo , Sang Min Lee , Jin Hwan Kim , Sungjun Moon , Jae-Kwang Lim , Chang Min Park , Jong Chul Ye