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Related papers: Diffusion Dispersion Imaging: Mapping OGSE Frequen…

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The purpose of this study is to propose a brain tissue-selective, optimized slice-by-slice B0 field shimming for high-resolution brain diffusion MRI. We incorporated actual gradient fields of X, Y, and Z gradient coils in the calculation of…

Changes in the nervous system due to neurological diseases take place at very small spatial scales, on the order of the micro and nanometers. Developing non-invasive imaging methods for obtaining this microscopic information as quantitative…

Diffusion functional MRI (dfMRI) is a promising technique to map functional activations by acquiring diffusion-weighed spin-echo images. In previous studies, dfMRI showed higher spatial accuracy at activation mapping compared to classic…

Medical Physics · Physics 2019-08-15 Alberto De Luca , Lara Schlaffke , Jeroen CW Siero , Martijn Froeling , Alexander Leemans

The dependence of the diffusion MRI signal on the diffusion time carries signatures of restricted diffusion and exchange. Here we seek to highlight these signatures in the human brain by performing experiments using free gradient waveforms…

Purpose: Oscillating gradient spin echo (OGSE) sequences have demonstrated an ability to probe time-dependent microstructural features, though they often suffer from low SNR due to increased echo times. In this work we introduce frequency…

Medical Physics · Physics 2022-10-18 Kevin B. Borsos , Desmond H. Y. Tse , Paul I. Dubovan , Corey A. Baron

Microscopic diffusion anisotropy ({\mu}A) has been recently gaining increasing attention for its ability to decouple the average compartment anisotropy from orientation dispersion. Advanced diffusion MRI sequences, such as double diffusion…

Oscillating-gradient spin-echo diffusion-weighted magnetic resonance imaging (OGSE-DWI) has been promoted as a promising technique for studying the microstructure of complex hydrated matter in the frequency domain. The target of the…

Medical Physics · Physics 2023-09-15 Jeff Kershaw , Takayuki Obata

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

Purpose: Diffusion MRI (dMRI) suffers from eddy currents induced by strong diffusion gradients, which introduce artefacts that can impair subsequent diffusion metric analysis. Existing retrospective correction techniques that correct for…

Medical Physics · Physics 2022-06-29 Jake J. Valsamis , Paul I. Dubovan , Corey A. Baron

Diffusion Magnetic Resonance Imaging (dMRI) plays a critical role in studying microstructural changes in the brain. It is, therefore, widely used in clinical practice; yet progress in learning general-purpose representations from dMRI has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Gustavo Chau Loo Kung , Mohammad Abbasi , Camila Blank , Juze Zhang , Alan Q. Wang , Sophie Ostmeier , Akshay Chaudhari , Kilian Pohl , Ehsan Adeli

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Purpose: To accelerate radially sampled diffusion weighted spin-echo (Rad-DW-SE) acquisition method for generating high quality apparent diffusion coefficient (ADC) maps. Methods: A deep learning method was developed to generate accurate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Yuemeng Li , Miguel Romanello Joaquim , Stephen Pickup , Hee Kwon Song , Rong Zhou , Yong Fan

Purpose: To assess the technical feasibility of whole-brain diffusional variance decomposition (DIVIDE) based on q-space trajectory encoding (QTE) at clinical MRI systems with varying performance. DIVIDE is used to separate diffusional…

Medical Physics · Physics 2019-04-03 Filip Szczepankiewicz , Jens Sjölund , Freddy Ståhlberg , Jimmy Lätt , Markus Nilsson

MRI provides a unique non-invasive window into the brain, yet is limited to millimeter resolution, orders of magnitude coarser than cell dimensions. Here we show that diffusion MRI is sensitive to the micrometer-scale variations in axon…

Medical Physics · Physics 2020-07-10 Hong-Hsi Lee , Antonios Papaioannou , Sung-Lyoung Kim , Dmitry S. Novikov , Els Fieremans

Accurate segmentation of brain tumors in MRI scans is essential for reliable clinical diagnosis and effective treatment planning. Recently, diffusion models have demonstrated remarkable effectiveness in image generation and segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

Diffusion magnetic resonance imaging (dMRI) provides critical insights into the microstructural and connectional organization of the human brain. However, the availability of high-field, open-access datasets that include raw k-space data…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shanshan Wang , Shoujun Yu , Jian Cheng , Sen Jia , Changjun Tie , Jiayu Zhu , Haohao Peng , Yijing Dong , Jianzhong He , Fan Zhang , Yaowen Xing , Xiuqin Jia , Qi Yang , Qiyuan Tian , Hua Guo , Guobin Li , Hairong Zheng

Biophysical modelling of diffusion MRI is necessary to provide specific microstructural tissue properties. However, estimating model parameters from data with limited diffusion gradient strength, such as clinical scanners, has proven…

Medical Physics · Physics 2019-03-21 Sune Nørhøj Jespersen , Jonas Lynge Olesen , Brian Hansen , Noam Shemesh

Early diagnosis and noninvasive monitoring of neurological disorders require sensitivity to elusive cellular-level alterations that occur much earlier than volumetric changes observable with the millimeter-resolution of medical imaging…

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