English

Oscillating-gradient spin-echo diffusion-weighted imaging (OGSE-DWI) with a limited number of oscillations: II. Asymptotics

Medical Physics 2023-09-15 v1 Image and Video Processing

Abstract

Oscillating-gradient spin-echo diffusion-weighted magnetic resonance imaging (OGSE-DWI) has been promoted as a promising technique for studying the microstructure of complex hydrated matter in the frequency domain. The target of the OGSE-DWI technique is the spectral density of molecular diffusion, u2(ω)u_{2}(\omega), which is predicted to obey a set of asymptotic universality relations that are linked to the global organisation of the sample. So, in principle the complex microstructure of a medium can be classified by measuring the spectral density in its low- and high-frequency limits. However, due to practical limitations on the spectral resolution and range of the technique, it is not possible to directly sample the spectral density with OGSE-DWI. Rather, information about the spectral density can be obtained only indirectly through the quantities UkkU_{kk} & Uk0U_{k0}, which are filtered representations of u2(ω)u_{2}(\omega). The purpose of this study is to investigate how the universal behaviour of u2(ω)u_{2}(\omega) emerges in the asymptotic behaviour of OGSE-DWI signal.

Keywords

Cite

@article{arxiv.2309.07484,
  title  = {Oscillating-gradient spin-echo diffusion-weighted imaging (OGSE-DWI) with a limited number of oscillations: II. Asymptotics},
  author = {Jeff Kershaw and Takayuki Obata},
  journal= {arXiv preprint arXiv:2309.07484},
  year   = {2023}
}

Comments

16 pages + supplementary material