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The technique presented here identifies tethered mould designs, optimised for growing cultured tissue with very highly-aligned cells. It is based on a microscopic biophysical model for polarised cellular hydrogels. There is an unmet need…

Biological Physics · Physics 2023-06-26 James P. Hague , Allison E. Andrews , Hugh Dickinson

Advancements in modern semiconductor devices increasingly depend on the utilization of amorphous materials and the reduction of material thickness, pushing the boundaries of their physical capabilities. The mechanical properties of these…

Applied Physics · Physics 2024-05-31 C. Pashartis , M. J. van Setten , M. Houssa , G. Pourtois

We present a fiber-distributed model of the reinforcing collagen of the human cornea. The model describes the basic connections between the components of the tissue by defining an elementary block (cell) and upscaling it to the physical…

Biological Physics · Physics 2023-06-28 Maria Laura De Bellis , Marcello Vasta , Alessio Gizzi , Anna Pandolfi

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

Soft Condensed Matter · Physics 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi

We report surface shear rheological measurements on dense insoluble monolayers of micron sized colloidal spheres at the oil/water interface and of the protein $\beta$-lactoglobulin at the air/water surface. As expected, the elastic modulus…

Soft Condensed Matter · Physics 2009-11-10 Pietro Cicuta , Edward J. Stancik , Gerald G. Fuller

The field of optimal design of linear elastic structures has seen many exciting successes that resulted in new architected materials and structural designs. With the availability of cloud computing, including high-performance computing,…

Computational Engineering, Finance, and Science · Computer Science 2021-02-09 Diab W. Abueidda , Seid Koric , Nahil A. Sobh

Mechanical forces influence the development and behavior of biological tissues. In many situations these forces are exerted or resisted by elastic compliant structures such as the own-tissue cellular matrix or other surrounding tissues.…

Silicene, a two-dimensional (2D) allotrope of silicon, has attracted significant interest for its electronic and mechanical properties, alongside its compatibility with various substrates. In this study, we investigate the structural and…

Materials Science · Physics 2025-05-14 Carlos P. Herrero , Rafael Ramirez

Chiral polymers are ubiquitous in nature and in the cellular context they are often found in association with membranes. Here we show that surface bound polymers with an intrinsic twist and anisotropic bending stiffness can exhibit a sharp…

Soft Condensed Matter · Physics 2016-04-26 David A. Quint , Ajay Gopinathan , Gregory M. Grason

The geometric shape, symmetry, and topology of colloidal particles often allow for controlling colloidal phase behavior and physical properties of these soft matter systems. In liquid crystalline dispersions, colloidal particles with low…

Soft Condensed Matter · Physics 2024-10-14 Ye Yuan , Ivan I. Smalyukh

Thermo-responsive hydrogels are a promising material for creating controllable actuators for use in micro-scale devices, since they expand and contract significantly (absorbing or expelling fluid) in response to relatively small temperature…

Soft Condensed Matter · Physics 2022-08-18 Matthew D. Butler , Thomas D. Montenegro-Johnson

Soft membranes are commonly employed in shape-morphing applications, where the material is programmed to achieve a target shape upon activation by an external trigger, and as coating layers that alter the surface characteristics of bulk…

Soft Condensed Matter · Physics 2016-02-05 Alessandro Lucantonio , Luciano Teresi , Antonio DeSimone

Prominences show a surprising amount of fine structure and it is widely believed that their threads, as seen in H$\alpha$ observations, provide indirect information concerning magnetic field topology. We investigate the spontaneous…

Solar and Stellar Astrophysics · Physics 2020-04-29 Niels Claes , Rony Keppens , Chun Xia

Machine learning techniques have been used to quantify the relationship between local structural features and variations in local dynamical activity in disordered glass-forming materials. To date these methods have been applied to an array…

Soft Condensed Matter · Physics 2021-01-07 Indrajit Tah , Tristan A. Sharp , Andrea J. Liu , Daniel M. Sussman

In the present work, the overall nonlinear elastic behavior of a 1D multi-modular structure incorporating possible imperfections at the discrete (micro-scale) level, is derived with respect to both tensile and compressive applied loads. The…

Soft Condensed Matter · Physics 2019-04-10 S. Palumbo , L. Deseri , D. R. Owen , M. Fraldi

Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…

Cell Behavior · Quantitative Biology 2022-11-16 Carles Falcó , Ruth E. Baker , José A. Carrillo

Topological defects are crucial to the thermodynamics and structure of condensed matter systems. For instance, when incorporated into crystalline membranes like graphene, disclinations with positive and negative topological charge…

Soft Condensed Matter · Physics 2018-08-29 Isaac R. Bruss , Gregory M. Grason

In proliferating epithelia of mammalian skin, cells of irregular polygonal-like shapes pack into complex nearly flat two-dimensional structures that are pliable to deformations. In this work, we employ various sensitive correlation…

Statistical Mechanics · Physics 2016-12-07 Duyu Chen , Wen Yih Aw , Danelle Devenport , Salvatore Torquato

The holographic duality has proven successful in linking seemingly unrelated problems in physics.Recently, intriguing correspondences between the physics of soft matter and gravity are emerging,including strong similarities between the…

Soft Condensed Matter · Physics 2022-06-07 Deng Pan , Teng Ji , Matteo Baggioli , Li Li , Yuliang Jin

A method to couple interparticle contact models with Stokesian dynamics (SD) is introduced to simulate colloidal aggregates under flow conditions. The contact model mimics both the elastic and plastic behavior of the cohesive connections…

Soft Condensed Matter · Physics 2015-03-20 Ryohei Seto , Robert Botet , Günter K. Auernhammer , Heiko Briesen
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