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Predicting the response of nonlinear dynamical systems subject to random, broadband excitation is important across a range of scientific disciplines, such as structural dynamics and neuroscience. Building data-driven models requires…

Machine Learning · Computer Science 2024-09-27 Joseph Massingham , Ole Nielsen , Tore Butlin

The processes of gene expression are inherently stochastic, even for essential genes required for growth. How does the cell maximize fitness in light of noise? To answer this question, we build a mathematical model to explore the trade-off…

Molecular Networks · Quantitative Biology 2024-11-13 Teresa W. Lo , Han James Choi , Dean Huang , Paul A. Wiggins

Complex networks are abundant in nature and many share an important structural property: they contain a few nodes that are abnormally highly connected (hubs). Some of these hubs are called influencers because they couple strongly to the…

Adaptation and Self-Organizing Systems · Physics 2024-09-04 Ralf Tönjes , Carlos E. Fiore , Tiago Pereira

A simple model for image formation in linear shift-invariant systems is considered, in which both the detected signal and the noise variance are varying slowly compared to the point-spread function of the system. It is shown that within the…

Medical Physics · Physics 2017-08-10 Timur Gureyev , Yakov Nesterets , Frank de Hoog

We study the influence of intrinsic noise on the structure and dynamics of responsive colloids (RCs) which actively change their size and mutual interactions. The colloidal size is explicitly resolved in our RC model as an internal degree…

Soft Condensed Matter · Physics 2025-09-22 Nils Göth , Upayan Baul , Joachim Dzubiella

The amplitude of fluctuation-induced patterns might be expected to be proportional to the strength of the driving noise, suggesting that such patterns would be difficult to observe in nature. Here, we show that a large class of…

Statistical Mechanics · Physics 2017-01-11 Tommaso Biancalani , Farshid Jafarpour , Nigel Goldenfeld

Why is the spine of a neuron so small that only small numbers of molecules can exist and reactions inevitably become stochastic? Despite such noisy conditions, we previously showed that the spine exhibits robust, sensitive and efficient…

Subcellular Processes · Quantitative Biology 2017-03-02 Masashi Fujii , Kaoru Ohashi , Yasuaki Karasawa , Minori Hikichi , Shinya Kuroda

We describe how noise propagates through a network by calculating the variance of the outputs. Using stochastic calculus and dynamical systems theory, we study the network topologies that accentuate or alleviate the effect of random…

Molecular Networks · Quantitative Biology 2011-08-15 Dionysios Barmpoutis , Richard M. Murray

Neuronal responses are conspicuously variable. We focus on one particular aspect of that variability: the precision of action potential timing. We show that for common models of noisy spike generation, elementary considerations imply that…

Disordered Systems and Neural Networks · Physics 2009-10-31 Guillermo A. Cecchi , Mariano Sigman , Jose-Manuel Alonso , Luis Martinez , Dante R. Chialvo , Marcelo O. Magnasco

In previous articles we have investigated the firing properties of the standard Hodgkin-Huxley (HH) systems of ordinary and partial differential equations in response to input currents composed of a drift (mean) and additive Gaussian white…

Neurons and Cognition · Quantitative Biology 2015-06-04 Henry C. Tuckwell , Jürgen Jost

The theory of Balanced Neural Networks is a very popular explanation for the high degree of variability and stochasticity in the brain's activity. Roughly speaking, it entails that typical neurons receive many excitatory and inhibitory…

Probability · Mathematics 2025-05-27 James MacLaurin , Pedro Vilanova

Recent advances in neural information retrieval (IR) models have significantly enhanced their effectiveness over various IR tasks. The robustness of these models, essential for ensuring their reliability in practice, has also garnered…

Information Retrieval · Computer Science 2024-08-19 Yu-An Liu , Ruqing Zhang , Jiafeng Guo , Maarten de Rijke , Yixing Fan , Xueqi Cheng

We demonstrate the existence of stochastic resonance (SR) in confined systems arising from entropy variations associated to the presence of irregular boundaries. When the motion of a Brownian particle is constrained to a region with uneven…

Statistical Mechanics · Physics 2009-06-05 P. S. Burada , G. Schmid , D. Reguera , J. M. Rubi , P. Hänggi

In the cerebral cortex, neurons are subject to a continuous bombardment of synaptic inputs originating from the network's background activity. This leads to ongoing, mostly subthreshold membrane dynamics that depends on the statistics of…

Biological Physics · Physics 2009-11-07 Ulrich Hillenbrand

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the…

Neurons and Cognition · Quantitative Biology 2024-01-09 Afifurrahman , Mohd Hafiz Mohd , Farah Aini Abdullah

Quantitative single cell measurements have shown that cell cycle duration (the time between cell divisions) for diverse cell types is a noisy variable. The underlying distribution is mean scalable with a universal shape for many cell types…

Cell Behavior · Quantitative Biology 2016-03-07 Nash Rochman , Fangwei Si , Sean X. Sun

We provide a general framework for studying recurrent neural networks (RNNs) trained by injecting noise into hidden states. Specifically, we consider RNNs that can be viewed as discretizations of stochastic differential equations driven by…

Machine Learning · Statistics 2021-12-02 Soon Hoe Lim , N. Benjamin Erichson , Liam Hodgkinson , Michael W. Mahoney

In a fissile material, the inherent multiplicity of neutrons born through induced fissions leads to correlations in their detection statistics. The correlations between neutrons can be used to trace back some characteristics of the fissile…

Computation · Statistics 2022-11-17 Paul Lartaud , Philippe Humbert , Josselin Garnier

In recurrent neural networks (RNNs) used to model biological neural networks, noise is typically introduced during training to emulate biological variability and regularize learning. The expectation is that removing the noise at test time…

Neural and Evolutionary Computing · Computer Science 2026-01-09 Noah Eckstein , Manoj Srinivasan

We have studied the entropy-driven mechanism leading to stationary patterns formation in stochastic systems with local dynamics and non-Fickian diffusion. We have shown that a multiplicative noise fulfilling a fluctuation-dissipation…

Statistical Mechanics · Physics 2008-06-20 D. O. Kharchenko , S. V. Kokhan , A. V. Dvornichenko