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Interpretability methods for image classification assess model trustworthiness by attempting to expose whether the model is systematically biased or attending to the same cues as a human would. Saliency methods for feature attribution…

Machine Learning · Statistics 2021-04-08 Jacob Pfau , Albert T. Young , Jerome Wei , Maria L. Wei , Michael J. Keiser

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in…

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 James R. Clough , Ilkay Oksuz , Esther Puyol-Anton , Bram Ruijsink , Andrew P. King , Julia A. Schnabel

An essential step in deploying medical imaging models is ensuring alignment with clinical knowledge and interpretability. We focus on mapping clinical concepts into the latent space of generative models to identify Concept Activation…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Bulat Maksudov , Kathleen Curran , Alessandra Mileo

Recurrent Neural Networks (RNNs) are often used for sequential modeling of adverse outcomes in electronic health records (EHRs) due to their ability to encode past clinical states. These deep, recurrent architectures have displayed…

Explainable artificial intelligence (XAI) is increasingly used to analyze the behavior of neural networks. Concept activation uses human-interpretable concepts to explain neural network behavior. This study aimed at assessing the…

Understanding complex machine learning models such as deep neural networks with explanations is crucial in various applications. Many explanations stem from the model perspective, and may not necessarily effectively communicate why the…

Machine Learning · Computer Science 2022-02-28 Chih-Kuan Yeh , Been Kim , Pradeep Ravikumar

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

With a growing interest in understanding neural network prediction strategies, Concept Activation Vectors (CAVs) have emerged as a popular tool for modeling human-understandable concepts in the latent space. Commonly, CAVs are computed by…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Frederik Pahde , Maximilian Dreyer , Leander Weber , Moritz Weckbecker , Christopher J. Anders , Thomas Wiegand , Wojciech Samek , Sebastian Lapuschkin

Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Wiebke Laffers , Dennis Eggert , Stephan Westermann , Nina A. Mueller , Andreas O. H. Gerstner , Christian Betz , Alexander Schlaefer

How do two deep neural networks differ in how they arrive at a decision? Measuring the similarity of deep networks has been a long-standing open question. Most existing methods provide a single number to measure the similarity of two…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Neehar Kondapaneni , Oisin Mac Aodha , Pietro Perona

Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

The interpretation of deep learning models is a challenge due to their size, complexity, and often opaque internal state. In addition, many systems, such as image classifiers, operate on low-level features rather than high-level concepts.…

Machine Learning · Statistics 2019-04-05 Been Kim , Martin Wattenberg , Justin Gilmer , Carrie Cai , James Wexler , Fernanda Viegas , Rory Sayres

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Concept Activation Vectors (CAVs) are a tool from explainable AI, offering a promising approach for understanding how human-understandable concepts are encoded in a model's latent spaces. They are computed from hidden-layer activations of…

Machine Learning · Statistics 2026-01-28 Ekkehard Schnoor , Malik Tiomoko , Jawher Said , Alex Jung , Wojciech Samek

Machine learning models are trained with relatively simple objectives, such as next token prediction. However, on deployment, they appear to capture a more fundamental representation of their input data. It is of interest to understand the…

Machine Learning · Computer Science 2024-12-23 Thomas Walker

Recently, deep architectures, such as recurrent and recursive neural networks have been successfully applied to various natural language processing tasks. Inspired by bidirectional recurrent neural networks which use representations that…

Machine Learning · Computer Science 2013-12-03 Ozan İrsoy , Claire Cardie

Concept Activation Vectors (CAVs) offer insights into neural network decision-making by linking human friendly concepts to the model's internal feature extraction process. However, when a new set of CAVs is discovered, they must still be…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Laines Schmalwasser , Jakob Gawlikowski , Joachim Denzler , Julia Niebling

Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Alexander Rakhlin , Alexey Shvets , Vladimir Iglovikov , Alexandr A. Kalinin
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