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The black-box nature of deep learning models prevents them from being completely trusted in domains like biomedicine. Most explainability techniques do not capture the concept-based reasoning that human beings follow. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Avinash Kori , Parth Natekar , Ganapathy Krishnamurthi , Balaji Srinivasan

In this paper we present a methodology that uses convolutional neural networks (CNNs) for segmentation by iteratively growing predicted mask regions in each coordinate direction. The CNN is used to predict class probability scores in a…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 John Lagergren , Erica Rutter , Kevin Flores

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Machine learning algorithms such as linear regression, SVM and neural network have played an increasingly important role in the process of scientific discovery. However, none of them is both interpretable and accurate on nonlinear datasets.…

Quantitative Methods · Quantitative Biology 2017-10-31 Chengyu Liu , Wei Wang

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Regression via classification (RvC) is a common method used for regression problems in deep learning, where the target variable belongs to a set of continuous values. By discretizing the target into a set of non-overlapping classes, it has…

Machine Learning · Computer Science 2022-04-11 Axel Berg , Magnus Oskarsson , Mark O'Connor

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

The current models of image representation based on Convolutional Neural Networks (CNN) have shown tremendous performance in image retrieval. Such models are inspired by the information flow along the visual pathway in the human visual…

Computer Vision and Pattern Recognition · Computer Science 2017-03-06 Zakaria Laskar , Juho Kannala

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Do black-box neural network models learn clinically relevant features for fracture diagnosis? The answer not only establishes reliability quenches scientific curiosity but also leads to explainable and verbose findings that can assist the…

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

This paper aims to bridge the affective gap between image content and the emotional response of the viewer it elicits by using High-Level Concepts (HLCs). In contrast to previous work that relied solely on low-level features or used…

Computer Vision and Pattern Recognition · Computer Science 2017-05-09 Afsheen Rafaqat Ali , Usman Shahid , Mohsen Ali , Jeffrey Ho

Humans use abstract concepts for understanding instead of hard features. Recent interpretability research has focused on human-centered concept explanations of neural networks. Concept Activation Vectors (CAVs) estimate a model's…

Machine Learning · Computer Science 2023-11-28 Avani Gupta , Saurabh Saini , P J Narayanan

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

To address the challenge of the ``black-box" nature of deep learning in medical settings, we combine GCExplainer - an automated concept discovery solution - along with Logic Explained Networks to provide global explanations for Graph Neural…

Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the…

This paper introduces a visual sentiment concept classification method based on deep convolutional neural networks (CNNs). The visual sentiment concepts are adjective noun pairs (ANPs) automatically discovered from the tags of web photos,…

Computer Vision and Pattern Recognition · Computer Science 2014-11-03 Tao Chen , Damian Borth , Trevor Darrell , Shih-Fu Chang

Deep learning shows promise for medical image analysis but lacks interpretability, hindering adoption in healthcare. Attribution techniques that explain model reasoning may increase trust in deep learning among clinical stakeholders. This…

Machine Learning · Computer Science 2023-08-08 Yusuf Brima , Marcellin Atemkeng

In preoperative imaging, the demarcation of rectal cancer with magnetic resonance images provides an important basis for cancer staging and treatment planning. Recently, deep learning has greatly improved the state-of-the-art method in…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Joohyung Lee , Ji Eun Oh , Min Ju Kim , Bo Yun Hur , Dae Kyung Sohn

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk