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We present an asymptotic analysis of a stochastic two-compartmental cell division system with regulatory mechanisms inspired by Getto et al. (2013). The hematopoietic system is modeled as a two-compartment system, where the first…

Populations and Evolution · Quantitative Biology 2025-06-30 Ren-Yi Wang , Marek Kimmel , Guodong Pang

Differential Evolution (DE) is quite powerful for real parameter single objective optimization. However, the ability of extending or changing search area when falling into a local optimum is still required to be developed in DE for…

Artificial Intelligence · Computer Science 2020-03-03 Chengjun Li , Yang Li

The neural ordinary differential equation (ODE) framework has emerged as a powerful tool for developing accelerated surrogate models of complex physical systems governed by partial differential equations (PDEs). A popular approach for PDE…

Fluid Dynamics · Physics 2025-03-26 Ashish S. Nair , Shivam Barwey , Pinaki Pal , Jonathan F. MacArt , Troy Arcomano , Romit Maulik

There are many natural, physical, and biological systems that exhibit multiple time scales. For example, the dynamics of a population of ticks can be described in continuous time during their individual life cycle yet discrete time is used…

Dynamical Systems · Mathematics 2009-07-10 Raquel M. Lopez , Sergei K. Suslov , Erika T. Camacho

We present an individual based model of evolutionary ecology. The reproduction rate of individuals characterized by their genome depends on the composition of the population in genotype space. Ecological features such as the taxonomy and…

Statistical Mechanics · Physics 2016-08-31 Matt Hall , Kim Christensen , Simone A. di Collobiano , Henrik Jeldtoft Jensen

We consider a multiscale stochastic compartmental model with three types of cells (stem cells, immature cells and mature cells) which combines cell proliferation and cell differentiation. We derive a hydrodynamic limit when the number of…

Probability · Mathematics 2026-03-10 Vincent Bansaye , Ana Fernández Baranda , Stéphane Giraudier , Sylvie Méléard

We consider birth and death stochastic dynamics of particle systems with attractive interaction. The heuristic generator of the dynamics has a constant birth rate and density dependent decreasing death rate. The corresponding statistical…

Mathematical Physics · Physics 2015-06-18 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy , Elena Zhizhina

In this paper, we inspect well-known population genetics and social dynamics models. In these models, interacting individuals, while participating in a self-organizing process, give rise to the emergence of complex behaviors and patterns.…

Populations and Evolution · Quantitative Biology 2012-07-11 Sven Banisch , Tanya Araújo

A discrete-time model of reacting evolving fields, transported by a bidimensional chaotic fluid flow, is studied. Our approach is based on the use of a Lagrangian scheme where {\it fluid particles} are advected by a $2d$ symplectic map…

We demonstrate with a thought experiment that fitness-based population dynamical approaches to evolution are not able to make quantitative, falsifiable predictions about the long-term behavior of evolutionary systems. A key characteristic…

Populations and Evolution · Quantitative Biology 2015-05-14 Peter Klimek , Stefan Thurner , Rudolf Hanel

We analyze a class of cell-bulk coupled PDE-ODE models, motivated by quorum and diffusion sensing phenomena in microbial systems, that characterize communication between localized spatially segregated dynamically active signaling…

Pattern Formation and Solitons · Physics 2020-07-20 Sarafa A. Iyaniwura , Michael J. Ward

This paper addresses mechanisms for boundedly rational decision makers in discrete choice problem. First, we introduce two mathematical models of population dynamics with conformity biases. We next analyze the models in terms of…

Systems and Control · Electrical Eng. & Systems 2021-11-23 Shunya Yamashita , Kodai Irifune , Takeshi Hatanaka , Yasuaki Wasa , Kenji Hirata , Kenko Uchida

Understanding the behavior of particles in a dispersed phase system via population balances holds fundamental importance in studies of particulate sciences across various fields. Particle behavior, however, is sophisticated as a single…

Computational Engineering, Finance, and Science · Computer Science 2026-02-16 Simon Ing Xun Tiong , Firnaaz Ahamed , Yong Kuen Ho

We address a novel approach for stochastic individual-based modelling of a single species population. Individuals are distinguished by their remaining lifetimes, which are regulated by the interplay between the inexorable running of time…

Populations and Evolution · Quantitative Biology 2021-01-08 Luis R. T. Neves , Leonardo Paulo Maia

Recent theoretical studies have shown that demographic stochasticity can greatly increase the tendency of asexually reproducing phenotypically diverse organisms to spontaneously evolve into localised clusters, suggesting a simple mechanism…

Populations and Evolution · Quantitative Biology 2016-03-23 Luis F. Lafuerza , Alan J. McKane

We consider a stochastic individual-based model for the evolution of a haploid, asexually reproducing population. The space of possible traits is given by the vertices of a (possibly directed) finite graph $G=(V,E)$. The evolution of the…

Probability · Mathematics 2020-03-10 Loren Coquille , Anna Kraut , Charline Smadi

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Stochastic dynamic models have been extensively used for the description of processes with uncertainties arising in the operations research, behavioral sciences, and many other application areas. A large class of the problems from these…

Numerical Analysis · Mathematics 2021-06-01 Thi Kim Thoa Thieu , Roderick Melnik

Stochastic models of diffusion with excluded-volume effects are used to model many biological and physical systems at a discrete level. The average properties of the population may be described by a continuum model based on partial…

Chemical Physics · Physics 2012-12-20 Maria Bruna , S. Jonathan Chapman

Recent methods have been developed to map single-cell lineage statistics to population growth. Because population growth selects for exponentially rare phenotypes, these methods inherently depend on sampling large deviations from finite…

Statistical Mechanics · Physics 2025-01-16 Trevor GrandPre , Ethan Levien , Ariel Amir