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Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Diffusion-weighted imaging (DWI) is a powerful non-invasive tool which is widely used in clinical routine. Mostly, apparent diffusion coefficient maps are acquired, which cannot be directly related to cellular structure. More recently it…

The connectivity and structural integrity of the white matter of the brain is nowadays known to be implicated into a wide range of brain-related disorders. However, it was not before the advent of diffusion Magnetic Resonance Imaging (dMRI)…

Computer Vision and Pattern Recognition · Computer Science 2014-01-27 Q. Zhou , O. Michailovich , Y. Rathi

Purpose: To propose a domain-conditioned and temporal-guided diffusion modeling method, termed dynamic Diffusion Modeling (dDiMo), for accelerated dynamic MRI reconstruction, enabling diffusion process to characterize spatiotemporal…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Liping Zhang , Iris Yuwen Zhou , Sydney B. Montesi , Li Feng , Fang Liu

Spatiotemporal data imputation plays a crucial role in various fields such as traffic flow monitoring, air quality assessment, and climate prediction. However, spatiotemporal data collected by sensors often suffer from temporal…

Machine Learning · Computer Science 2024-12-18 Zijin Liu , Xiang Zhao , You Song

Imaging findings inconsistent with those expected at specific chronological age ranges may serve as early indicators of neurological disorders and increased mortality risk. Estimation of chronological age, and deviations from expected…

We present a method to estimate a multivariate Gaussian distribution of diffusion tensor features in a set of brain regions based on a small sample of healthy individuals, and use this distribution to identify imaging abnormalities in…

Applications · Statistics 2017-04-24 Matineh Shaker , Deniz Erdogmus , Jennifer Dy , Sylvain Bouix

Current deep learning approaches for diffusion MRI modeling circumvent the need for densely-sampled diffusion-weighted images (DWIs) by directly predicting microstructural indices from sparsely-sampled DWIs. However, they implicitly make…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Mengwei Ren , Heejong Kim , Neel Dey , Guido Gerig

Objective: The purpose of this manuscript is to accelerate cardiac diffusion tensor imaging (CDTI) by integrating low-rankness and compressed sensing. Methods: Diffusion-weighted images exhibit both transform sparsity and low-rankness.…

Signal Processing · Electrical Eng. & Systems 2018-01-12 Sen Ma , Christopher T. Nguyen , Anthony G. Christodoulou , Daniel Luthringer , Jon Kobashigawa , Sang-Eun Lee , Hyuk-Jae Chang , Debiao Li

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

Brain network analysis is essential for diagnosing and intervention for Alzheimer's disease (AD). However, previous research relied primarily on specific time-consuming and subjective toolkits. Only few tools can obtain the structural brain…

Artificial Intelligence · Computer Science 2023-03-14 Xuhang Chen , Baiying Lei , Chi-Man Pun , Shuqiang Wang

White matter tract integrity (WMTI) can characterize brain microstructure in areas with highly aligned fiber bundles. Several WMTI biomarkers have now been validated against microscopy and provided promising results in studies of brain…

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Amir Sadikov , Xinlei Pan , Hannah Choi , Lanya T. Cai , Pratik Mukherjee

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…

Effective characterisation of the brain grey matter cytoarchitecture with quantitative sensitivity to soma density and volume remains an unsolved challenge in diffusion MRI (dMRI). Solving the problem of relating the dMRI signal with…

Quantitative Methods · Quantitative Biology 2022-05-05 Maëliss Jallais , Pedro Luiz Coelho Rodrigues , Alexandre Gramfort , Demian Wassermann

Data-dependent metrics are powerful tools for learning the underlying structure of high-dimensional data. This article develops and analyzes a data-dependent metric known as diffusion state distance (DSD), which compares points using a…

Machine Learning · Statistics 2020-03-10 Lenore Cowen , Kapil Devkota , Xiaozhe Hu , James M. Murphy , Kaiyi Wu