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Diffusion Tensor Imaging (DTI) tractography offers detailed insights into the structural connectivity of the brain, but presents challenges in effective representation and interpretation in deep learning models. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Vishwa Mohan Singh , Alberto Gaston Villagran Asiares , Luisa Sophie Schuhmacher , Kate Rendall , Simon Weißbrod , David Rügamer , Inga Körte

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Purpose: To facilitate the implementation/validation of signal representations and models using parametric matrix-variate distributions to approximate the diffusion tensor distribution (DTD) $\mathcal{P}(\mathbf{D})$. Theory: We establish…

Computational Engineering, Finance, and Science · Computer Science 2020-05-25 A. Reymbaut

Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Pedro Ferreira , Andrew Scott , Sonia Nielles-Vallespin , Guang Yang

Statistical analysis of Diffusion Tensor Imaging (DTI) data requires a computational framework that is both numerically tractable (to account for the high dimensional nature of the data) and geometric (to account for the nonlinear nature of…

Computer Vision and Pattern Recognition · Computer Science 2012-10-11 Anne Collard , Silvère Bonnabel , Christophe Phillips , Rodolphe Sepulchre

The understanding of neurodegenerative diseases undoubtedly passes through the study of human brain white matter fiber tracts. To date, diffusion magnetic resonance imaging (dMRI) is the unique technique to obtain information about the…

Machine Learning · Computer Science 2012-07-04 Romain Giot , Christophe Charrier , Maxime Descoteaux

In vivo diffusion tensor imaging (DTI) is a promising technique to investigate noninvasively the fiber structures of the in vivo human heart. However, signal loss due to motions remains a persistent problem in in vivo cardiac DTI. We…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Zeyu Deng , Lihui Wang , Zixiang Kuai , Qijian Chen , Xinyu Cheng , Feng Yang , Jie Yang , Yuemin Zhu

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

Accurate drug-target interaction (DTI) prediction is essential for computational drug discovery, yet existing models often rely on single-modality predefined molecular descriptors or sequence-based embeddings with limited…

We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental…

Machine Learning · Computer Science 2020-12-22 Ashirbani Saha , Pantea Fadaiefard , Jessica E. Rabski , Alireza Sadeghian , Michael D. Cusimano

Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jason Qiu

We propose a novel approach to denoising diffusion magnetic resonance images (dMRI) using convolutional neural networks, that exploits the benefits of data acquired at multiple b-values to offset the need for many redundant observations.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-23 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Filip Szczepankiewicz

Diffusion Magnetic Resonance Imaging (dMRI) plays a critical role in studying microstructural changes in the brain. It is, therefore, widely used in clinical practice; yet progress in learning general-purpose representations from dMRI has…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Gustavo Chau Loo Kung , Mohammad Abbasi , Camila Blank , Juze Zhang , Alan Q. Wang , Sophie Ostmeier , Akshay Chaudhari , Kilian Pohl , Ehsan Adeli

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Magnetic resonance imaging (MRI) is a vital diagnostic tool, but its inherently long acquisition times reduce clinical efficiency and patient comfort. Recent advancements in deep learning, particularly diffusion models, have improved…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yuxuan Zhang , Jinkui Hao , Bo Zhou

High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…

Applications · Statistics 2021-11-12 William Consagra , Arun Venkataraman , Zhengwu Zhang

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shishuai Wang , Hua Ma , Juan A. Hernandez-Tamames , Stefan Klein , Dirk H. J. Poot

Generative diffusion models have achieved remarkable success in producing high-quality images. However, these models typically operate in continuous intensity spaces, diffusing independently across pixels and color channels. As a result,…

Graphics · Computer Science 2025-05-20 Javier E. Santos , Agnese Marcato , Roman Colman , Nicholas Lubbers , Yen Ting Lin