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The correct reconstruction of individual (crossing) nerve fibers is a prerequisite when constructing a detailed network model of the brain. The recently developed technique Scattered Light Imaging (SLI) allows the reconstruction of crossing…

Biological Physics · Physics 2021-11-30 Miriam Menzel , Marouan Ritzkowski , Jan André Reuter , David Gräßel , Katrin Amunts , Markus Axer

Brain science is an evolving research area inviting great enthusiasm with its potential for providing insights and thereby, preventing, and treating multiple neuronal disorders affecting millions of patients. Discovery of relationships,…

Neurons and Cognition · Quantitative Biology 2016-03-17 Bisakha Ray , Alexander V. Alekseyenko , Sisi Ma , Alexander Statnikov , Constantin Aliferis

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Deep learning architectures based on convolutional neural networks tend to rely on continuous, smooth features. While this characteristics provides significant robustness and proves useful in many real-world tasks, it is strikingly…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Zuzanna Buchnajzer , Kacper Dobek , Stanisław Hapke , Daniel Jankowski , Krzysztof Krawiec

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse…

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

We present a scalable method for brain cell identification in multiview confocal light sheet microscopy images. Our algorithmic pipeline includes a hierarchical registration approach and a novel multiview version of semantic deconvolution…

Computer Vision and Pattern Recognition · Computer Science 2015-11-05 Marco Paciscopi , Ludovico Silvestri , Francesco Saverio Pavone , Paolo Frasconi

Developing automated and semi-automated solutions for reconstructing wiring diagrams of the brain from electron micrographs is important for advancing the field of connectomics. While the ultimate goal is to generate a graph of neuron…

Computer Vision and Pattern Recognition · Computer Science 2016-08-09 William Gray Roncal , Colin Lea , Akira Baruah , Gregory D. Hager

In structural brain networks the connections of interest consist of white-matter fibre bundles between spatially segregated brain regions. The presence, location and orientation of these white matter tracts can be derived using diffusion…

Neurons and Cognition · Quantitative Biology 2012-02-09 M. Hinne , T. Heskes , M. A. J. van Gerven

This tutorial covers biomedical image reconstruction, from the foundational concepts of system modeling and direct reconstruction to modern sparsity and learning-based approaches. Imaging is a critical tool in biological research and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Michael T. McCann , Michael Unser

We investigate the applicability of artificial neural networks (ANNs) in reconstructing a sample image of a sponge-like microstructure. We propose to reconstruct the image by predicting the phase of the current pixel based on its causal…

Materials Science · Physics 2021-10-20 Kryštof Latka , Martin Doškář , Jan Zeman

Dynamic imaging is essential for analyzing various biological systems and behaviors but faces two main challenges: data incompleteness and computational burden. For many imaging systems, high frame rates and short acquisition times require…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Luke Lozenski , Mark A. Anastasio , Umberto Villa

An approach to incorporate deep learning within an iterative image reconstruction framework to reconstruct images from severely incomplete measurement data is presented. Specifically, we utilize a convolutional neural network (CNN) as a…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Brendan Kelly , Thomas P. Matthews , Mark A. Anastasio

Human brain atlases provide spatial reference systems for data characterizing brain organization at different levels, coming from different brains. Cytoarchitecture is a basic principle of the microstructural organization of the brain, as…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 Christian Schiffer , Hannah Spitzer , Kai Kiwitz , Nina Unger , Konrad Wagstyl , Alan C. Evans , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

Deep learning algorithms offer a powerful means to automatically analyze the content of medical images. However, many biological samples of interest are primarily transparent to visible light and contain features that are difficult to…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Roarke Horstmeyer , Richard Y. Chen , Barbara Kappes , Benjamin Judkewitz

Inspired by recent advances in deep learning, we propose a framework for reconstructing dynamic sequences of 2D cardiac magnetic resonance (MR) images from undersampled data using a deep cascade of convolutional neural networks (CNNs) to…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Jo Schlemper , Jose Caballero , Joseph V. Hajnal , Anthony Price , Daniel Rueckert

Seeing is believing, however, the underlying mechanism of how human visual perceptions are intertwined with our cognitions is still a mystery. Thanks to the recent advances in both neuroscience and artificial intelligence, we have been able…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Yu-Ting Lan , Kan Ren , Yansen Wang , Wei-Long Zheng , Dongsheng Li , Bao-Liang Lu , Lili Qiu

In voltage imaging, where the membrane potentials of individual neurons are recorded at from hundreds to thousand frames per second using fluorescence microscopy, data processing presents a challenge. Even a fraction of a minute of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Yosuke Bando , Ramdas Pillai , Atsushi Kajita , Farhan Abdul Hakeem , Yves Quemener , Hua-an Tseng , Kiryl D. Piatkevich , Changyang Linghu , Xue Han , Edward S. Boyden

Multimode fibers (MMFs) have the potential to carry complex images for endoscopy and related applications, but decoding the complex speckle patterns produced by mode-mixing and modal dispersion in MMFs is a serious challenge. Several groups…

Image and Video Processing · Electrical Eng. & Systems 2020-09-02 Changyan Zhu , Eng Aik Chan , You Wang , Weina Peng , Ruixiang Guo , Baile Zhang , Cesare Soci , Yidong Chong

Reconstructing human vision from brain activities has been an appealing task that helps to understand our cognitive process. Even though recent research has seen great success in reconstructing static images from non-invasive brain…

Computer Vision and Pattern Recognition · Computer Science 2023-05-22 Zijiao Chen , Jiaxin Qing , Juan Helen Zhou
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