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Large language models (LLMs) like ChatGPT have excited scientists across fields; in medicine, one source of excitement is the potential applications of LLMs trained on electronic health record (EHR) data. But there are tough questions we…

Computers and Society · Computer Science 2023-09-25 Weipeng Zhou , Danielle Bitterman , Majid Afshar , Timothy A. Miller

Randomized experiments can provide unbiased estimates of sample average treatment effects. However, estimates of population treatment effects can be biased when the experimental sample and the target population differ. In this case, the…

Methodology · Statistics 2022-11-10 Wenqi Shi , Xi Lin

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Electronic health records (EHRs) are longitudinal records of a patient's interactions with healthcare systems. A patient's EHR data is organized as a three-level hierarchy from top to bottom: patient journey - all the experiences of…

Machine Learning · Computer Science 2020-09-29 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang , Chengqi Zhang

Increasingly, medical research is dependent on data collected for non-research purposes, such as electronic health records data (EHR). EHR data and other large databases can be prone to measurement error in key exposures, and unadjusted…

Methodology · Statistics 2020-05-13 Kyunghee Han , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw

The growing availability of observational databases like electronic health records (EHR) provides unprecedented opportunities for secondary use of such data in biomedical research. However, these data can be error-prone and need to be…

Methodology · Statistics 2024-05-28 Sarah C. Lotspeich , Gustavo G. C. Amorim , Pamela A. Shaw , Ran Tao , Bryan E. Shepherd

Electronic Health Records (EHRs) aggregate diverse information at the patient level, holding a trajectory representative of the evolution of the patient health status throughout time. Although this information provides context and can be…

Machine Learning · Computer Science 2022-09-12 João Figueira Silva , Sérgio Matos

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

Machine Learning · Computer Science 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

Digital healthcare systems have enabled the collection of mass healthcare data in electronic healthcare records (EHRs), allowing artificial intelligence solutions for various healthcare prediction tasks. However, existing studies often…

Machine Learning · Computer Science 2025-08-27 Zi Cai , Yu Liu , Zhiyao Luo , Tingting Zhu

Objectives: In the United States, 25% of people with type 2 diabetes are undiagnosed. Conventional screening models use limited demographic information to assess risk. We evaluated whether electronic health record (EHR) phenotyping could…

Quantitative Methods · Quantitative Biology 2015-01-13 Ariana E. Anderson , Wesley T. Kerr , April Thames , Tong Li , Jiayang Xiao , Mark S. Cohen

Foundation models hold significant promise in healthcare, given their capacity to extract meaningful representations independent of downstream tasks. This property has enabled state-of-the-art performance across several clinical…

Electronic Health Records (EHR) contain rich longitudinal patient information and are widely used in predictive modeling applications. However, effectively leveraging historical data remains challenging due to long trajectories,…

Information Retrieval · Computer Science 2026-05-13 Saeed Shurrab , Mariam Al-Omari , Dana El Samad , Farah E. Shamout

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

Electronic health records (EHRs) are a pivotal data source that enables numerous applications in computational medicine, e.g., disease progression prediction, clinical trial design, and health economics and outcomes research. Despite wide…

Machine Learning · Computer Science 2024-06-18 Jun Han , Zixiang Chen , Yongqian Li , Yiwen Kou , Eran Halperin , Robert E. Tillman , Quanquan Gu

Due to the rapid growth of information available about individual patients, most physicians suffer from information overload when they review patient information in health information technology systems. In this manuscript, we present a…

Information Retrieval · Computer Science 2020-08-13 Ziwei Fan , Evan Burgun , Zhiyun Ren , Titus Schleyer , Xia Ning

The broad adoption of Electronic Health Records (EHR) has led to vast amounts of data being accumulated on a patient's history, diagnosis, prescriptions, and lab tests. Advances in recommender technologies have the potential to utilize this…

Information Retrieval · Computer Science 2020-09-01 Suman Bhoi , Lee Mong Li , Wynne Hsu

The past decade has seen an explosion in the amount of digital information stored in electronic health records (EHR). While primarily designed for archiving patient clinical information and administrative healthcare tasks, many researchers…

Machine Learning · Computer Science 2018-02-27 Benjamin Shickel , Patrick Tighe , Azra Bihorac , Parisa Rashidi

The data available in Electronic Health Records (EHRs) provides the opportunity to transform care, and the best way to provide better care for one patient is through learning from the data available on all other patients. Temporal modelling…

Computation and Language · Computer Science 2021-07-08 Zeljko Kraljevic , Anthony Shek , Daniel Bean , Rebecca Bendayan , James Teo , Richard Dobson

Electronic health record (EHR) systems contain a wealth of multimodal clinical data including structured data like clinical codes and unstructured data such as clinical notes. However, many existing EHR-focused studies has traditionally…

Machine Learning · Statistics 2025-08-20 Tianxi Cai , Feiqing Huang , Ryumei Nakada , Linjun Zhang , Doudou Zhou

Learning theory has traditionally followed a model-centric approach, focusing on designing optimal algorithms for a fixed natural learning task (e.g., linear classification or regression). In this paper, we adopt a complementary…

Machine Learning · Computer Science 2025-04-29 Steve Hanneke , Shay Moran , Alexander Shlimovich , Amir Yehudayoff