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The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…

Structured electronic health records (EHR) are essential for clinical prediction. While count-based learners continue to perform strongly on such data, no benchmarking has directly compared them against more recent mixture-of-agents LLM…

Artificial Intelligence · Computer Science 2025-11-04 Jifan Gao , Michael Rosenthal , Brian Wolpin , Simona Cristea

Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

Machine Learning · Computer Science 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Biomedical studies that use electronic health records (EHR) data for inference are often subject to bias due to measurement error. The measurement error present in EHR data is typically complex, consisting of errors of unknown functional…

Methodology · Statistics 2020-06-16 Eric J. Oh , Bryan E. Shepherd , Thomas Lumley , Pamela A. Shaw

Electronic health records (EHR) data have considerable variability in data completeness across sites and patients. Lack of "EHR data-continuity" or "EHR data-discontinuity", defined as "having medical information recorded outside the reach…

We propose a new iterative segmentation model which can be accurately learned from a small dataset. A common approach is to train a model to directly segment an image, requiring a large collection of manually annotated images to capture the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Danielle F. Pace , Adrian V. Dalca , Tom Brosch , Tal Geva , Andrew J. Powell , Jürgen Weese , Mehdi H. Moghari , Polina Golland

Biobanks with genetics-linked electronic health records (EHR) have opened up opportunities to study associations between genetic, social, or environmental factors and longitudinal lab biomarkers. However, in EHRs, the timing of patient…

Methodology · Statistics 2025-05-23 Jiacong Du , Xu Shi , Bhramar Mukherjee

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Surrogate variables in electronic health records (EHR) and biobank data play an important role in biomedical studies due to the scarcity or absence of chart-reviewed gold standard labels. We develop a novel approach named SASH for {\bf…

Methodology · Statistics 2023-09-04 Yue Liu , Molei Liu , Zijian Guo , Tianxi Cai

In recent years, increasingly augmentation of health data, such as patient Electronic Health Records (EHR), are becoming readily available. This provides an unprecedented opportunity for knowledge discovery and data mining algorithms to dig…

Machine Learning · Computer Science 2019-05-09 Xi Sheryl Zhang , Fengyi Tang , Hiroko Dodge , Jiayu Zhou , Fei Wang

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Introduced in the early 2010s, Electronic Health Records (EHRs) have become ubiquitous in hospitals. Despite clear benefits, they remain unpopular among healthcare professionals and present significant challenges. Positioned at the…

Human-Computer Interaction · Computer Science 2025-04-22 Louise Robert , Laurine Moniez , Quentin Luzurier , David Morquin

I examine the problem of treatment choice when a planner observes (i) covariates that describe each member of a population of interest and (ii) the outcomes of an experiment in which subjects randomly drawn from this population are randomly…

Applications · Statistics 2013-02-01 Charles F. Manski

This paper proposes a new robust smooth-threshold estimating equation to select important variables and automatically estimate parameters for high dimensional longitudinal data. A novel working correlation matrix is proposed to capture…

Methodology · Statistics 2021-11-30 Liya Fu , Jiaqi Li , You-Gan Wang

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

Selecting high-quality training data from a larger pool is a crucial step when instruction-tuning language models, as carefully curated datasets often produce models that outperform those trained on much larger, noisier datasets. Automated…

Computation and Language · Computer Science 2025-06-23 Hamish Ivison , Muru Zhang , Faeze Brahman , Pang Wei Koh , Pradeep Dasigi

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Modern randomization methods in clinical trials are invariably adaptive, meaning that the assignment of the next subject to a treatment group uses the accumulated information in the trial. Some of the recent adaptive randomization methods…

Methodology · Statistics 2024-02-12 Alan R. Vazquez , Weng Kee Wong

Modeling disease progression in healthcare administrative databases is complicated by the fact that patients are observed only at irregular intervals when they seek healthcare services. In a longitudinal cohort of 76,888 patients with…

Machine Learning · Computer Science 2018-12-04 Aman Verma , Guido Powell , Yu Luo , David Stephens , David L. Buckeridge

Electronic Health Records (EHRs) contain a large volume of heterogeneous patient data, which are useful at the point of care and for retrospective research. These data are typically stored in relational databases. Gaining an integrated view…

Computers and Society · Computer Science 2018-06-04 Dina Levy-Lambert , Jen J. Gong , Tristan Naumann , Tom J. Pollard , John V. Guttag
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