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Designing novel proteins with desired characteristics remains a significant challenge due to the large sequence space and the complexity of sequence-function relationships. Efficient exploration of this space to identify sequences that meet…

Machine Learning · Computer Science 2026-03-04 Erik Hartman , Di Tang , Johan Malmström

The experimenter must perform a legitimate search in the entire set of feasible censoring schemes to identify the optimal type II progressive censoring scheme, when applied to a life-testing experiment. Current recommendations are limited…

Applications · Statistics 2025-07-29 Ujjwal Roy , Ritwik Bhattacharya

Overset methods are commonly employed to enable the effective simulation of problems involving complex geometries and moving objects such as rotorcraft. This paper presents a novel overset domain connectivity algorithm based upon the direct…

Computational Physics · Physics 2018-11-14 Jacob A. Crabill , Freddie D. Witherden , Antony Jameson

The implementation of adaptive genetic algorithms (AGA) for optimization problems has proven to be superior than many other methods due to its nature of producing more robust and high quality solutions. Considering the complexity involved…

Computational Physics · Physics 2024-11-28 Brandon Willnecker , Mervlyn Moodley

The compact Genetic Algorithm (cGA), parameterized by its hypothetical population size $K$, offers a low-memory alternative to evolving a large offspring population of solutions. It evolves a probability distribution, biasing it towards…

Neural and Evolutionary Computing · Computer Science 2024-04-19 Cella Florescu , Marc Kaufmann , Johannes Lengler , Ulysse Schaller

Traditional Genetic Algorithms (GAs) mating schemes select individuals for crossover independently of their genotypic or phenotypic similarities. In Nature, this behaviour is known as random mating. However, non-random schemes - in which…

Neural and Evolutionary Computing · Computer Science 2009-09-30 C. M. Fernandes , J. J. Merelo , A. C. Rosa

Genetic algorithms are stochastic iterative algorithms in which a population of individuals evolve by emulating the process of biological evolution and natural selection. The R package GA provides a collection of general purpose functions…

Computation · Statistics 2018-07-19 Luca Scrucca

This paper presents our computational methodology using Genetic Algorithms (GA) for exploring the nature of RNA editing. These models are constructed using several genetic editing characteristics that are gleaned from the RNA editing system…

Neural and Evolutionary Computing · Computer Science 2007-05-23 C. Huang , L. M. Rocha

Genetic Algorithm (GA) is a popular meta-heuristic evolutionary algorithm that uses stochastic operators to find optimal solution and has proved its effectiveness in solving many complex optimization problems (such as classification,…

Neural and Evolutionary Computing · Computer Science 2023-05-02 Fahad Maqbool , Muhammad Saad Razzaq , Hajira Jabeen

Application of Genetic Algorithm (GA) for determination of parameters of an analytical representation of diatomic molecule potential is presented. GA can be used for finding potential characteristics of an electronic energy state which can…

Chemical Physics · Physics 2020-05-12 Tomasz Urbanczyk , Jaroslaw Koperski

We discuss a novel genetic algorithm that can be used to find global minima on the potential energy surface of disordered ceramics and alloys using a real-space symmetry adapted crossover. Due to a high number of symmetrically equivalent…

Materials Science · Physics 2011-05-31 Chris E. Mohn , Svein Stølen , Walter Kob

The paper presents a Stateflow based network test-bed to validate real-time optimal control algorithms. Genetic Algorithm (GA) based time domain performance index minimization is attempted for tuning of PI controller to handle a balanced…

Systems and Control · Computer Science 2012-02-28 Ayan Mukherjee , Anindya Pakhira , Saptarshi Das , Indranil Pan , Amitava Gupta

One of the important problems in multiprocessor systems is Task Graph Scheduling. Task Graph Scheduling is an NP-Hard problem. Both learning automata and genetic algorithms are search tools which are used for solving many NP-Hard problems.…

Computational Complexity · Computer Science 2011-06-13 Vahid Majid Nezhad , Habib Motee Gader , Evgueni Efimov

Artificial Intelligence (AI) techniques are known for its ability in tackling problems found to be unyielding to traditional mathematical methods. A recent addition to these techniques are the Computational Intelligence (CI) techniques…

Neural and Evolutionary Computing · Computer Science 2013-03-01 Wesam Elshamy

Block scheduling is difficult to implement in P2P network since there is no central coordinator. This problem can be solved by employing network coding technique which allows intermediate nodes to perform the coding operation instead of…

Networking and Internet Architecture · Computer Science 2020-08-04 M. Anandaraj , K. Selvaraj , P. Ganeshkumar , K. Rajkumar , S. Sriram

Genetic algorithms, which mimic evolutionary processes to solve optimization problems, can be enhanced by using powerful semi-local search algorithms as mutation operators. Here, we introduce reverse quantum annealing, a class of quantum…

Airline crew pairing optimization problem (CPOP) aims to find a set of flight sequences (crew pairings) that cover all flights in an airline's highly constrained flight schedule at minimum cost. Since crew cost is second only to the fuel…

Neural and Evolutionary Computing · Computer Science 2023-05-30 Divyam Aggarwal , Dhish Kumar Saxena , Thomas Back , Michael Emmerich

With the rise of large radio interferometric telescopes, particularly the SKA, there is a growing demand for computationally efficient image reconstruction techniques. Existing reconstruction methods, such as the CLEAN algorithm or proximal…

Instrumentation and Methods for Astrophysics · Physics 2025-07-30 Matthijs Mars , Tobías I. Liaudat , Jessica J. Whitney , Marta M. Betcke , Jason D. McEwen

Protein structure prediction can be shown to be an NP-hard problem; the number of conformations grows exponentially with the number of residues. The native conformations of proteins occupy a very small subset of these, hence an exploratory,…

Chemical Physics · Physics 2008-02-03 Mehul M. Khimasia , Peter V. Coveney

We recently reported that the simple genetic algorithm (SGA) is capable of performing a remarkable form of sublinear computation which has a straightforward connection with the general problem of interacting attributes in data-mining. In…

Neural and Evolutionary Computing · Computer Science 2009-05-18 Keki M. Burjorjee