Related papers: Quantitative MRI molecular imaging in the evaluati…
Accurate reconstruction of ambient temperature at death scenes is crucial for estimating the postmortem interval (PMI) in forensic science. Typically, this is done by correcting weather station temperatures using measurements from the…
Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…
Industry standards require medical device manufacturers to perform implant-induced artefact testing in phantoms at a pre-clinical stage to define the extent of artefacts that can be expected during MRI. Once a device is commercially…
Paralytic Ileus (PI) patients are at high risk of death when admitted to the Intensive care unit (ICU), with mortality as high as 40\%. There is minimal research concerning PI patient mortality prediction. There is a need for more accurate…
Traditional approaches for molecular imaging of Parkinson's disease (PD) in vivo require radioactive isotopes, lengthy scan times, or deliver only low spatial resolution. Recent advances in saturation transfer-based PD magnetic resonance…
Quantitative phase imaging (QPI) quantifies the sample-specific optical-phase-delay enabling objective studies of optically-transparent specimens such as biological samples, but lacks chemical sensitivity limiting its application to…
Quantitative magnetic resonance imaging (qMRI) allows images to be compared across sites and time points, which is particularly important for assessing long-term conditions or for longitudinal studies. The multiparametric mapping (MPM)…
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines…
Vital signs and laboratory values are routinely used to guide clinical decision-making for polytrauma patients, such as the decision to use damage control techniques versus early definitive fracture fixation. Prior multivariate models have…
Modern MRI relies on the well-established Echo-Planar-Imaging (EPI) method for fast acquisition. EPI is the workhorse of diffusion and functional MRI in neuroscience as well as of many dynamic applications for clinical body imaging. Its…
Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…
Functional magnetic resonance spectroscopy (fMRS) quantifies metabolic variations upon presentation of a stimulus and can therefore provide complementary information compared to functional magnetic resonance imaging (fMRI). However, to our…
Quantum methods are increasingly proposed for healthcare, but translational biomarker studies demand transparent benchmarking and robust small-dataset evaluation. We analysed a preclinical COPD cohort of 213 animals with blood and…
We propose a novel a-posteriori error estimation technique where the target quantities of interest are ratios of high-dimensional integrals, as occur e.g. in PDE constrained Bayesian inversion and PDE constrained optimal control subject to…
This work examines the hypothesis that intravoxel incoherent motion MRI (IVIM) can quantify local cerebral blood flow (qCBF), infarct volume, and define the ischemic penumbra for determination of the perfusion-diffusion mismatch (PWI/DWI)…
Quantitative analysis of fetal lung Diffusion-Weighted MRI (DWI) data shows potential in providing quantitative imaging biomarkers that indirectly reflect fetal lung maturation. However, fetal motion during the acquisition hampered…
Accurate preoperative prediction of erectile dysfunction (ED) is important for counseling patients undergoing radical prostatectomy. While clinical features are established predictors, the added value of preoperative MRI remains…
Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…
Purpose: To develop an accelerated Cartesian MRF implementation using a multi-shot EPI sequence for rapid simultaneous quantification of T1 and T2 parameters. Methods: The proposed Cartesian MRF method involved the acquisition of highly…
The study reports the performance of Parkinson's disease (PD) patients to operate Motor-Imagery based Brain-Computer Interface (MI-BCI) and compares three selected pre-processing and classification approaches. The experiment was conducted…