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Development of high strength carbon fibers (CFs) requires an understanding of the relationship between the processing conditions, microstructure and resulting properties. We developed a molecular model that combines kinetic Monte Carlo…

Materials Science · Physics 2017-03-29 Saaketh Desai , Chunyu Li , Tongtong Shen , Alejandro Strachan

Simulating large-scale protein dynamics using traditional all-atom molecular dynamics (MD) remains computationally prohibitive. We present a unified, universal framework for coarse-grained molecular dynamics (CG-MD) that achieves…

Atomic Physics · Physics 2026-04-16 Jinzhen Zhu

We report a simulation study for bottle-brush polymers grafted on a rigid backbone. Using a standard coarse-grained bead-spring model extensive molecular dynamics simulations for such macromolecules under good solvent conditions are…

Soft Condensed Matter · Physics 2015-05-30 Hamed Maleki , Panagiotis E. Theodorakis

Given that the physical properties of polymeric liquids extend on a wide range of lengthscales, it is computationally convenient to represent them by coarse-grained (CG) descriptions at various granularities to investigate local and global…

Soft Condensed Matter · Physics 2019-06-06 Mohammadhasan Dinpajooh , Marina G. Guenza

The hierarchical graphene model is a simple toy model which is useful to understand the mechanics of renormalization group flows in super-renormalizable systems. It is based on a model of interacting electrons in graphene, for which the…

Mathematical Physics · Physics 2022-06-17 Ian Jauslin

A novel fully bio-based Poly (Glycerol-Itaconic acid) (PGI) was designed and highly efficiently synthesized by solvent-free polycondensation. The Poly (ethylene glycol) (PEG) was used as the phase change materials (PCM) working substance…

Applied Physics · Physics 2021-09-02 Guang-Zhong Yin , José Luis Díaz Palencia , De-Yi Wang

We review a coarse-graining strategy (multiblob approach) for polymer solutions in which groups of monomers are mapped onto a single atom (a blob) and effective blob-blob interactions are obtained by requiring the coarse-grained model to…

Soft Condensed Matter · Physics 2015-03-19 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

Condense phase molecular systems organize in wide range of distinct molecular configurations, including amorphous melt and glass as well as crystals often exhibiting polymorphism, that originate from their intricate intra- and…

Mesoscale and Nanoscale Physics · Physics 2024-03-25 Brian H. Lee , James P. Larentzos , John K. Brennan , Alejandro Strachan

Even though atomistic and coarse-grained (CG) models have been used to simulate liquid nanodroplets in vapor, very few rigorous studies of the liquid-liquid interface structure are available, and most of them are limited to planar…

Chemical Physics · Physics 2019-07-16 Peiyuan Gao , Xiu Yang , Alexandre M. Tartakovsky

We report a flexible language-model based deep learning strategy, applied here to solve complex forward and inverse problems in protein modeling, based on an attention neural network that integrates transformer and graph convolutional…

Biomolecules · Quantitative Biology 2023-10-20 Markus J. Buehler

The characterization of protein-nanoparticle assemblies in solution remains a challenge. We demonstrate a technique based on a graphene microelectrode for structural-functional analysis of model systems composed of nanoparticles enclosed in…

Multifidelity models integrate data from multiple sources to produce a single approximator for the underlying process. Dense low-fidelity samples are used to reduce interpolation error, while sparse high-fidelity samples are used to…

Machine Learning · Statistics 2024-02-27 Viv Bone , Chris van der Heide , Kieran Mackle , Ingo H. J. Jahn , Peter M. Dower , Chris Manzie

We develop coarse-grained force fields for poly (vinyl alcohol) and poly (acrylic acid) oligomers. In both cases, one monomer is mapped onto a coarse-grained bead. The new force fields are designed to match structural properties such as…

Soft Condensed Matter · Physics 2009-10-31 Dirk Reith , Hendrik Meyer , Florian Mueller-Plathe

We introduce a powerful Monte Carlo (MC) algorithm for the atomistic simulation of bulk models of oligo- and poly-thiophenes by redesigning MC moves originally developed for considerably simpler polymer structures and architectures, such as…

Soft Condensed Matter · Physics 2019-03-06 Flora D. Tsourtou , Stavros D. Peroukidis , Loukas D. Peristeras , Vlasis G. Mavrantzas

We introduce a lattice model of protein conformations which is able to reproduce second structures of proteins (alpha--helices and beta--sheets). This model is based on the following two main ideas. First, we model backbone parts of amino…

Soft Condensed Matter · Physics 2012-08-01 S. Albeverio , S. V. Kozyrev

Extensive Monte Carlo results are presented for a lattice model of a bottle-brush polymer under good solvent or Theta solvent conditions. Varying the side chain length, backbone length, and the grafting density for a rigid straight…

Soft Condensed Matter · Physics 2009-11-13 Hsiao-Ping Hsu , Wolfgang Paul , Kurt Binder

We perform extensive coarse-grained (CG) Langevin dynamics simulations of intrinsically disordered proteins (IDPs), which possess fluctuating conformational statistics between that for excluded volume random walks and collapsed globules.…

Biomolecules · Quantitative Biology 2015-06-22 W. Wendell Smith , Po-Yi Ho , Corey S. O'Hern

Ribosomes are critical biomolecular nanomachines responsible for protein synthesis in all known organisms. The function and dynamics of ribosomes can be studied using molecular dynamics computer simulations. Although this task remains…

Biological Physics · Physics 2025-03-28 Josef Cikhart , Aneta Leskourová , Michal H. Kolář

A mesoscopic coarse-grain model for computationally-efficient simulations of biomembranes is presented. It combines molecular dynamics simulations for the lipids, modeled as elastic chains of beads, with multiparticle collision dynamics for…

Soft Condensed Matter · Physics 2015-06-04 Mu-Jie Huang , Raymond Kapral , Alexander S. Mikhailov , Hsuan-Yi Chen

A novel self-assembly strategy for polypeptide nanostructure design was presented in [Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments, Nature Chemical Biology 9 (2013) 362--366]. The first mathematical…

Combinatorics · Mathematics 2018-08-28 Gašper Fijavž , Tomaž Pisanski , Jernej Rus