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Medical imaging systems are commonly assessed by use of objective image quality measures. Supervised deep learning methods have been investigated to implement numerical observers for task-based image quality assessment. However, labeling…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Shenghua He , Weimin Zhou , Hua Li , Mark A. Anastasio

The integration of machine learning (ML) models enhances the efficiency, affordability, and reliability of feature detection in microscopy, yet their development and applicability are hindered by the dependency on scarce and often flawed…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Matthew J. Lynch , Ryan Jacobs , Gabriella Bruno , Priyam Patki , Dane Morgan , Kevin G. Field

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Domain Randomization (DR) is known to require a significant amount of training data for good performance. We argue that this is due to DR's strategy of random data generation using a uniform distribution over simulation parameters, as a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Rawal Khirodkar , Kris M. Kitani

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

In the last years, automated segmentation has become a necessary tool for volume electron microscopy (EM) imaging. So far, the best performing techniques have been largely based on fully supervised encoder-decoder CNNs, requiring a…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Joris Roels , Julian Hennies , Yvan Saeys , Wilfried Philips , Anna Kreshuk

The performance of existing supervised neuron segmentation methods is highly dependent on the number of accurate annotations, especially when applied to large scale electron microscopy (EM) data. By extracting semantic information from…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Yinda Chen , Wei Huang , Shenglong Zhou , Qi Chen , Zhiwei Xiong

Sparse Mobile CrowdSensing (MCS) is a novel MCS paradigm where data inference is incorporated into the MCS process for reducing sensing costs while its quality is guaranteed. Since the sensed data from different cells (sub-areas) of the…

Artificial Intelligence · Computer Science 2018-05-25 Leye Wang , Wenbin Liu , Daqing Zhang , Yasha Wang , En Wang , Yongjian Yang

Label estimation is an important component in an unsupervised person re-identification (re-ID) system. This paper focuses on cross-camera label estimation, which can be subsequently used in feature learning to learn robust re-ID models.…

Computer Vision and Pattern Recognition · Computer Science 2017-09-28 Mang Ye , Andy J Ma , Liang Zheng , Jiawei Li , P C Yuen

State-of-the-art object detection and segmentation methods for microscopy images rely on supervised machine learning, which requires laborious manual annotation of training data. Here we present a self-supervised method based on time arrow…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Benjamin Gallusser , Max Stieber , Martin Weigert

We propose a simple algorithm to train stochastic neural networks to draw samples from given target distributions for probabilistic inference. Our method is based on iteratively adjusting the neural network parameters so that the output…

Machine Learning · Statistics 2016-11-29 Dilin Wang , Qiang Liu

Automated experiments in scanning transmission electron microscopy (STEM) require rapid image segmentation to optimize data representation for human interpretation, decision-making, site-selective spectroscopies, and atomic manipulation.…

Materials Science · Physics 2024-09-23 Kamyar Barakati , Utkarsh Pratiush , Austin C. Houston , Gerd Duscher , Sergei V. Kalinin

Microscopy data collections are becoming larger and more frequent. Accurate and precise quantitative analysis tools like cell instance segmentation are necessary to benefit from them. This is challenging due to the variability in the data,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Ram J. Zaveri , Voke Brume , Gianfranco Doretto

Developing physics-based models for molecular simulation requires fitting many unknown parameters to diverse experimental datasets. Traditionally, this process is piecemeal and difficult to reproduce, leading to a fragmented landscape of…

Biological Physics · Physics 2025-04-10 Ryan K. Krueger , Megan C. Engel , Ryan Hausen , Michael P. Brenner

Brain age estimation based on magnetic resonance imaging (MRI) is an active research area in early diagnosis of some neurodegenerative diseases (e.g. Alzheimer, Parkinson, Huntington, etc.) for elderly people or brain underdevelopment for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Ruizhe Li , Matteo Bastiani , Dorothee Auer , Christian Wagner , Xin Chen

Data augmentation has proved extremely useful by increasing training data variance to alleviate overfitting and improve deep neural networks' generalization performance. In medical image analysis, a well-designed augmentation policy usually…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Yunhe Gao , Zhiqiang Tang , Mu Zhou , Dimitris Metaxas

Accurate segmentation of electron microscopy (EM) volumes of the brain is essential to characterize neuronal structures at a cell or organelle level. While supervised deep learning methods have led to major breakthroughs in that direction…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Daniel Franco-Barranco , Julio Pastor-Tronch , Aitor Gonzalez-Marfil , Arrate Muñoz-Barrutia , Ignacio Arganda-Carreras

A key step in understanding the spatial organization of cells and tissues is the ability to construct generative models that accurately reflect that organization. In this paper, we focus on building generative models of electron microscope…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Ligong Han , Robert F. Murphy , Deva Ramanan

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

Left ventricle segmentation and morphological assessment are essential for improving diagnosis and our understanding of cardiomyopathy, which in turn is imperative for reducing risk of myocardial infarctions in patients. Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-02-14 Sulaiman Vesal , Nishant Ravikumar , Andreas Maier
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