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Accurately counting the number of cells in microscopy images is required in many medical diagnosis and biological studies. This task is tedious, time-consuming, and prone to subjective errors. However, designing automatic counting methods…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Mark A. Anastasio , Hua Li

Accurately counting cells in microscopic images is important for medical diagnoses and biological studies, but manual cell counting is very tedious, time-consuming, and prone to subjective errors, and automatic counting can be less accurate…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Mark Anastasio , Hua Li

Modern methods often formulate the counting of cells from microscopic images as a regression problem and more or less rely on expensive, manually annotated training images (e.g., dot annotations indicating the centroids of cells or…

Image and Video Processing · Electrical Eng. & Systems 2021-05-18 Xin Ding , Qiong Zhang , William J. Welch

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Microscopy images from different imaging conditions, organs, and tissues often have numerous cells with various shapes on a range of backgrounds. As a result, designing a deep learning model to count cells in a source domain becomes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Zuhui Wang

An automatic approach to counting any kind of cells could alleviate work of the experts and boost the research in fields such as regenerative medicine. In this paper, a method for microscopy cell counting using multiple frames (hence…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Alexander Gomez Villa , Augusto Salazar , Igor Stefanini

We present a new annotated microscopic cellular image dataset to improve the effectiveness of machine learning methods for cellular image analysis. Cell counting is an important step in cell analysis. Typically, domain experts manually…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Abdurahman Ali Mohammed , Catherine Fonder , Donald S. Sakaguchi , Wallapak Tavanapong , Surya K. Mallapragada , Azeez Idris

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Generating realistic synthetic microscopy images is critical for training deep learning models in label-scarce environments, such as cell counting with many cells per image. However, traditional domain adaptation methods often struggle to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Mohammad Dehghanmanshadi , Wallapak Tavanapong

Supervised learning is often used to count objects in images, but for counting small, densely located objects, the required image annotations are burdensome to collect. Counting plant organs for image-based plant phenotyping falls within…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 Tewodros Ayalew , Jordan Ubbens , Ian Stavness

Counting immunopositive cells on biological tissues generally requires either manual annotation or (when available) automatic rough systems, for scanning signal surface and intensity in whole slide imaging. In this work, we tackle the…

Computational Engineering, Finance, and Science · Computer Science 2026-02-27 L. Martino , M. M. Garcia , P. S. Paradas , E. Curbelo

Self-training crowd counting has not been attentively explored though it is one of the important challenges in computer vision. In practice, the fully supervised methods usually require an intensive resource of manual annotation. In order…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Pha Nguyen , Thanh-Dat Truong , Miaoqing Huang , Yi Liang , Ngan Le , Khoa Luu

Reliable large-scale cell detection and segmentation is the fundamental first step to understanding biological processes in the brain. The ability to phenotype cells at scale can accelerate preclinical drug evaluation and system-level brain…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Son T. Ly , Bai Lin , Hung Q. Vo , Dragan Maric , Badri Roysam , Hien V. Nguyen

In many applications, we collect independent samples from interconnected populations. These population distributions share some latent structure, so it is advantageous to jointly analyze the samples. One effective way to connect the…

Methodology · Statistics 2021-03-08 Archer Gong Zhang , Jiahua Chen

Image annotation is one essential prior step to enable data-driven algorithms. In medical imaging, having large and reliably annotated data sets is crucial to recognize various diseases robustly. However, annotator performance varies…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Sonja Kunzmann , Mathias Öttl , Prathmesh Madhu , Felix Denzinger , Andreas Maier

The crowd counting task aims at estimating the number of people located in an image or a frame from videos. Existing methods widely adopt density maps as the training targets to optimize the point-to-point loss. While in testing phase, we…

Computer Vision and Pattern Recognition · Computer Science 2020-05-14 Xiyang Liu , Jie Yang , Wenrui Ding

Computer vision techniques have been used to produce accurate and generic crowd count estimators in recent years. Due to severe occlusions, appearance variations, perspective distortions and illumination conditions, crowd counting is a very…

Computer Vision and Pattern Recognition · Computer Science 2017-10-27 Haiyan Yao , Kang Han , Wanggen Wan , Li Hou

Cell counting in microscopy images is vital in medicine and biology but extremely tedious and time-consuming to perform manually. While automated methods have advanced in recent years, state-of-the-art approaches tend to increasingly…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou
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