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Recently, deep learning has been advancing the state of the art in artificial intelligence to a new level, and humans rely on artificial intelligence techniques more than ever. However, even with such unprecedented advancements, the lack of…

Human-Computer Interaction · Computer Science 2018-04-10 Jaegul Choo , Shixia Liu

The rapid advance of generative AI is reshaping the strategic vision for R&D across industries. The unique challenges of pharmaceutical R&D will see applications of generative AI deliver value along the entire value chain from early…

Quantitative Methods · Quantitative Biology 2023-12-21 Guy Doron , Sam Genway , Mark Roberts , Sai Jasti

Generative Adversarial Networks (GANs) is a novel class of deep generative models which has recently gained significant attention. GANs learns complex and high-dimensional distributions implicitly over images, audio, and data. However,…

Machine Learning · Computer Science 2023-04-06 Divya Saxena , Jiannong Cao

In the rapidly evolving landscape of genomics, deep learning has emerged as a useful tool for tackling complex computational challenges. This review focuses on the transformative role of Large Language Models (LLMs), which are mostly based…

In recent years, several machine learning approaches have been proposed to predict gene expression and epigenetic signals from the DNA sequence alone. These models are often used to deduce, and, to some extent, assess putative new…

Genomics · Quantitative Biology 2023-04-26 Laurent Bréhélin

Flaw detection in non-destructive testing, especially in complex signals like ultrasonic data, has thus far relied heavily on the expertise and judgement of trained human inspectors. While automated systems have been used for a long time,…

Signal Processing · Electrical Eng. & Systems 2019-03-28 Iikka Virkkunen , Tuomas Koskinen , Oskari Jessen-Juhler , Jari Rinta-Aho

In recent years, deep learning methods applying unsupervised learning to train deep layers of neural networks have achieved remarkable results in numerous fields. In the past, many genetic algorithms based methods have been successfully…

Neural and Evolutionary Computing · Computer Science 2017-11-22 Eli David , Iddo Greental

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

The rapid advancement of deepfake technologies, specifically designed to create incredibly lifelike facial imagery and video content, has ignited a remarkable level of interest and curiosity across many fields, including forensic analysis,…

Machine Learning · Computer Science 2025-01-03 Harshika Goyal , Mohammad Saif Wajid , Mohd Anas Wajid , Akib Mohi Ud Din Khanday , Mehdi Neshat , Amir Gandomi

In recent years, deep learning based generative models, particularly Generative Adversarial Networks (GANs), Variational Autoencoders (VAEs), and Diffusion Models (DMs), have been instrumental in in generating diverse, high-quality content…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Shamim Yazdani , Akansha Singh , Nripsuta Saxena , Zichong Wang , Avash Palikhe , Deng Pan , Umapada Pal , Jie Yang , Wenbin Zhang

Clustering is a fundamental machine learning task which has been widely studied in the literature. Classic clustering methods follow the assumption that data are represented as features in a vectorized form through various representation…

Machine Learning · Computer Science 2022-06-16 Sheng Zhou , Hongjia Xu , Zhuonan Zheng , Jiawei Chen , Zhao li , Jiajun Bu , Jia Wu , Xin Wang , Wenwu Zhu , Martin Ester

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Adversarial attacks and defenses in machine learning and deep neural network have been gaining significant attention due to the rapidly growing applications of deep learning in the Internet and relevant scenarios. This survey provides a…

Machine Learning · Computer Science 2023-03-14 Yulong Wang , Tong Sun , Shenghong Li , Xin Yuan , Wei Ni , Ekram Hossain , H. Vincent Poor

The rapid expansion of data from diverse sources has made anomaly detection (AD) increasingly essential for identifying unexpected observations that may signal system failures, security breaches, or fraud. As datasets become more complex…

Machine Learning · Computer Science 2025-03-18 Haoqi Huang , Ping Wang , Jianhua Pei , Jiacheng Wang , Shahen Alexanian , Dusit Niyato

Generative models such as Large Language Models, Diffusion Models, and generative adversarial networks have recently revolutionized the creation of synthetic data, offering scalable solutions to data scarcity, privacy, and annotation…

Machine Learning · Computer Science 2025-08-28 Dawei Li , Yue Huang , Ming Li , Tianyi Zhou , Xiangliang Zhang , Huan Liu

Protein engineering seeks to identify protein sequences with optimized properties. When guided by machine learning, protein sequence generation methods can draw on prior knowledge and experimental efforts to improve this process. In this…

Quantitative Methods · Quantitative Biology 2021-05-28 Zachary Wu , Kadina E. Johnston , Frances H. Arnold , Kevin K. Yang

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

Machine Learning · Computer Science 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya
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