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In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection…

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

Magnetic nanoparticles (MNPs) with proper surface functionalization have been extensively applied as labels for magnetic immunoassays, carriers for controlled drug/gene delivery, tracers and contrasts for magnetic imaging, etc. Here, we…

Magnetic Particle Imaging (MPI) is a novel imaging modality with important applications such as angiography, stem cell tracking, and cancer imaging. Recently, there have been efforts to increase the functionality of MPI via multi-color…

Medical Physics · Physics 2017-05-23 Yavuz Muslu , Mustafa Utkur , Omer Burak Demirel , Emine Ulku Saritas

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was…

Applied Physics · Physics 2020-03-24 Kai Wu , Diqing Su , Renata Saha , Jinming Liu , Vinit Kumar Chugh , Jian-Ping Wang

Nowadays, there is an increasing demand for more accessible routine diagnostics for patients with respect to high accuracy, ease of use, and low cost. However, the quantitative and high accuracy bioassays in large hospitals and laboratories…

In this work, we report a 5-minute magnetic particle spectroscopy (MPS)-based bioassay strategy. In our approach, surface functionalized magnetic nanoparticles (MNPs) are incubated with target analytes at 37 {\deg}C with agitation for 3…

Magnetic Particle Imaging (MPI) has been shown to provide remarkable contrast for imaging applications such as angiography, stem cell tracking, and cancer imaging. Recently, there is growing interest in the functional imaging capabilities…

Medical Physics · Physics 2017-04-26 Mustafa Utkur , Yavuz Muslu , Emine Ulku Saritas

Magnetic particle spectroscopy (MPS) is a technology that derives from magnetic particle imaging (MPI) and thrives as a standalone platform for many biological and biomedical applications, benefiting from the facile preparation and chemical…

Applied Physics · Physics 2020-03-24 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Vinit Kumar Chugh , Jian-Ping Wang

This Letter is a micromagnetic simulation-based study on the GHz-frequency ferromagnetic resonances for the detection of magnetic nanoparticles (MNPs) using spin current nano-oscillator (SCNO) operating in precession mode as a spintronic…

Applied Physics · Physics 2019-10-01 Renata Saha , Kai Wu , Diqing Su , Jian-Ping Wang

Remote sensing of magnetic nanoparticles has exciting applications for magnetic nanoparticle hyperthermia and molecular detection. We introduce, simulate, and experimentally demonstrate an innovation---a sensing coil that is geometrically…

Mesoscale and Nanoscale Physics · Physics 2014-03-26 Daniel B Reeves , John B Weaver

Nowadays, there is a growing interest in the field of magnetic particle spectroscopy (MPS)-based bioassays. MPS monitors the dynamic magnetic response of surface-functionalized magnetic nanoparticles (MNPs) upon excitation by an alternating…

Systems and Control · Electrical Eng. & Systems 2022-11-14 Vinit Kumar Chugh , Arturo di Girolamo , Venkatramana D. Krishna , Kai Wu , Maxim C-J Cheeran , Jian-Ping Wang

Magnetic nanoparticle (MNP) has attracted interest in various research fields due to its special superparamagnetic and strong magneto-optical effects, especially as contrast agents to enhance the contrast of medical imaging. By introducing…

Optics · Physics 2023-08-01 Xinchao Cui , Feidi Xiang , Chong Lu , Chunping Liu , Wenzhong Liu

Magnetic nanoparticles (MNPs) form the foundation of many technologies, frequently serving to purify proteins or cells from a biological sample or to remove environmental contaminants. Their success relies on their magnetic response, which…

Instrumentation and Detectors · Physics 2025-06-18 Alexis Scholtz , Jack Paulson , Victoria Nunez , Andrea M. Armani

Nanomechanical spectroscopy (NMS) is a recently developed approach to determine optical absorption spectra of nanoscale materials via mechanical measurements. It is based on measuring changes in the resonance frequency of a membrane…

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

Magnetic nanoparticles (MNPs) play an important role in biomedical applications including imaging modalities such as MRI and magnetic particle imaging (MPI). The latter one exploits the non-linear magnetization response of a large ensemble…

Mesoscale and Nanoscale Physics · Physics 2021-10-27 Hannes Albers , Tobias Knopp , Martin Möddel , Marija Boberg , Tobias Kluth

Nanomaterials, in addition to their small size, possess unique physicochemical properties that differ from the bulk materials, making them ideal for a host of novel applications. Magnetic nanoparticle (MNP) is one important class of…

Applied Physics · Physics 2019-10-08 Kai Wu , Diqing Su , Jinming Liu , Renata Saha , Jian-Ping Wang

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

In Magnetic Particle Imaging (MPI), the distribution of magnetic nanoparticles (MNPs) is imaged by moving a field free point (FFP) in space. All MNPs in close vicinity of the FFP contribute to the signal induced on the receive coil. The…

Signal Processing · Electrical Eng. & Systems 2021-12-02 Atakan Topcu , Asli Alpman , Mustafa Utkur , Emine Ulku Saritas
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