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Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…
Purpose: Electron density is the most important tissue property influencing photon and ion dose distributions in radiotherapy patients. Dual-energy computed tomography (DECT) enables the determination of electron density by combining the…
Differentiation of breast tissues is challenging in X-ray imaging because tissues might share similar or even the same linear attenuation coefficients $\mu$. Spectral computed tomography (CT) allows for more quantitative characterization in…
Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…
Many current and future dark matter and neutrino detectors are designed to measure scintillation light with a large array of photomultiplier tubes (PMTs). The energy resolution and particle identification capabilities of these detectors…
Quantitative imaging is an important feature of spectral X-ray and CT systems, especially photon-counting CT (PCCT) imaging systems, which is achieved through material decomposition (MD) using spectral measurements. In this work, we present…
Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…
Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…
Quantifying material mass and electron density from computed tomography (CT) reconstructions can be highly valuable in certain medical practices, such as radiation therapy planning. However, uniquely parameterising the X-ray attenuation in…
Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…
Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…
A direct method is proposed for reconstruction of the effective atomic number by means of multi-energy radiography of the material. The accuracy of the method is up to 95% . Advantages over conventional radiographic methods, which ensure…
Photon-counting detector based computed tomography (PCCT) has greatly advanced in recent years. However, spectral inconsistency, referring to inter-pixel variations in detected counts per energy bin, can easily leads to ring or band…
Significant progress in many classes of materials could be made with the availability of experimentally-derived large datasets composed of atomic identities and three-dimensional coordinates. Methods for visualizing the local atomic…
Recent development of photon-counting CT (PCCT) brings great opportunities for plaque characterization with much-improved spatial resolution and spectral imaging capability. While existing coronary plaque PCCT imaging results are based on…
Purpose: Photon-counting computed tomography (PCCT) shows promise for medical imaging in regards to material separation and imaging of multiple contrast agents. However, many PCCT setups are under development and are not optimized for…
Spectral photon-counting X-ray CT (sCT) opens up new possibilities for the quantitative measurement of materials in an object, compared to conventional energy-integrating CT or dual energy CT. However, achieving reliable and accurate…
In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is therefore challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable to…
Purpose: In treatment planning of charged-particle radiotherapy, patient heterogeneity is conventionally modeled as variable-density water converted from CT images to best reproduce the stopping power, which may lead to inaccuracies in the…
The purpose of this project is to investigate the use of charge couple devices (CCDs) to detect electrons directly. This can be done in transmission electron microscopy (TEM) for electrons over 100 KeV, but for space plasma instruments,…