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A multi-imaging strategy is proposed and experimentally tested to improve the accuracy of photon counting with an electron multiplying charge-coupled device (EMCCD), by taking into account the random nature of its on-chip gain and the…

Astrophysics · Physics 2009-11-13 Eric Lantz , Jean Luc Blanchet , Luca Furfaro , Fabrice Devaux

Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…

Human-Computer Interaction · Computer Science 2025-08-21 Mohit Sharma , Emma Nilsson , Martin Falk , Talha Bin Masood , Lee Jollans , Anders Persson , Tino Ebbers , Ingrid Hotz

Medical imaging faces challenges such as limited spatial resolution, interference from electronic noise and poor contrast-to-noise ratios. Photon Counting Computed Tomography (PCCT) has emerged as a solution, addressing these issues with…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Ana Carolina Alves , André Ferreira , Gijs Luijten , Jens Kleesiek , Behrus Puladi , Jan Egger , Victor Alves

High throughput screening of materials for technologically relevant areas, like identification of better catalysts, electronic materials, ceramics for high temperature applications and drug discovery, is an emerging topic of research. To…

Chemical Physics · Physics 2020-05-04 Edgar Josué Landinez Borda , Amit Samanta

We analyse photoionisation and ion detection as a means of accurately counting ultra-cold atoms. We show that it is possible to count clouds containing many thousands of atoms with accuracies better than $N^{-1/2}$ with current technology.…

Other Condensed Matter · Physics 2016-08-16 T. Campey , C. J. Vale , M. J. Davis , S. Kraft , C. Zimmermann , J. Fortágh , N. R. Heckenberg , H. Rubinsztein-Dunlop

Electron microscopy is a powerful tool for studying the properties of materials down to their atomic structure. In many cases, the quantitative interpretation of images requires simulations based on atomistic structure models. These…

Purpose: Photon counting (PC) computed tomography (CT) can provide material selective CT imaging at lowest patient dose but it suffers from suboptimal count rate. A dynamic beam attenuator (DBA) can help with count rate by modulating x-ray…

Medical Physics · Physics 2016-12-23 Haluk Atak , Polad M. Shikhaliev

In this paper we report a spectrometric approach to dual-energy digital radiography that has been developed and applied to identify specific organic substances and discern small differences in their effective atomic number. An experimental…

Instrumentation and Detectors · Physics 2008-10-06 S. V. Naydenov , V. D. Ryzhikov , G. M. Onyshchenko , P. Lecoq , C. Smith

Multi-energy radiography is a new direction in non-destructive testing. Its specific feature is separate detection of penetrating radiation in several energy channels. Multi-energy radiography allows quantitative determination of the atomic…

Instrumentation and Detectors · Physics 2009-11-11 Sergei V. Naydenov , Vladimir D. Ryzhikov , Craig F. Smith , Dennis Wood

X-ray computed tomography (CT) based on photon counting detectors (PCD) extends standard CT by counting detected photons in multiple energy bins. PCD data can be used to increase the contrast-to-noise ratio (CNR), increase spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-02-05 Natalie M. Jadue , Madhuri Nagare , Jonathan S. Maltz , Gregery T. Buzzard , Charles A. Bouman

Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

Medical Physics · Physics 2022-08-10 Fredrik Grönberg , Hans Bornefalk

Photomultiplier tubes (PMTs) are widely used in particle experiments for photon detection. PMT waveform analysis is crucial for high-precision measurements of the position and energy of incident particles in liquid scintillator (LS)…

Instrumentation and Detectors · Physics 2024-12-02 Wei Jiang , Guihong Huang , Zhen Liu , Wuming Luo , Liangjian Wen , Jianyi Luo

Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and…

Medical Physics · Physics 2022-03-01 Nathan Wang , Petteri Haverinen

Food x-ray inspection systems are designed to detect unwanted physical contaminants in packaged food to maintain a high level of food safety for consumers. Modern day x-ray inspection systems often utilize line scan sensors to detect these…

Applied Physics · Physics 2022-05-18 Joanna Nguyen , Devon Richtsmeier , Kris Iniewski , Magdalena Bazalova-Carter

X-ray photon-counting detectors (PCDs) are drawing an increasing attention in recent years due to their low noise and energy discrimination capabilities. The energy/spectral dimension associated with PCDs potentially brings great benefits…

Medical Physics · Physics 2020-07-08 Mengzhou Li , David S. Rundle , Ge Wang

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…

Medical Physics · Physics 2024-08-28 Qiaoxin Li , Ruifeng Chen , Peng Wang , Guotao Quan , Yanfeng Du , Dong Liang , Yinsheng Li

We propose a method for performing material identification from radiographs without energy-resolved measurements. Material identification has a wide variety of applications, including in biomedical imaging, nondestructive testing, and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Michael T. McCann , Elena Guardincerri , Samuel M. Gonzales , Lauren A. Misurek , Jennifer L. Schei , Marc L. Klasky

The smuggling of special nuclear materials (SNM) through international borders could enable nuclear terrorism and constitutes a significant threat to global security. This paper presents the experimental demonstration of a novel…

Instrumentation and Detectors · Physics 2018-04-30 Brian S. Henderson , Hin Y. Lee , Thomas D. MacDonald , Roberts G. Nelson , Areg Danagoulian

We experimentally demonstrate a detection scheme suitable for state analysis of single optically trapped atoms in less than 1 {\mu}s with an overall detection efficiency {\eta} exceeding 98%. The method is based on hyperfine-state-selective…

Particle identification using the energy loss in silicon detectors is a powerful technique for probing the Standard Model (SM) as well as searching for new particles beyond the SM. Traditionally, such techniques use the truncated mean of…

Instrumentation and Detectors · Physics 2018-11-02 Harley Patton , Benjamin Nachman