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Is Winfree's abstract Tile Assembly Model (aTAM) "powerful?" Well, if certain tiles are required to "cooperate" in order to be able to bind to a growing tile assembly (a.k.a., temperature 2 self-assembly), then Turing universal computation…

Emerging Technologies · Computer Science 2012-02-02 Matthew J. Patitz , Robert T. Schweller , Scott M. Summers

We consider non cooperative binding in so called `temperature 1', in deterministic (here called {\it confluent}) tile self-assembly systems (1-TAS) and prove the standing conjecture that such systems do not have universal computational…

Computational Complexity · Computer Science 2019-01-25 Jérôme Durand-Lose , Hendrik Jan Hoogeboom , Nataša Jonoska

The algorithmic self-assembly of shapes has been considered in several models of self-assembly. For the problem of \emph{shape construction}, we consider an extended version of the Two-Handed Tile Assembly Model (2HAM), which contains…

Computational Geometry · Computer Science 2016-08-18 Austin Luchsinger , Robert Schweller , Tim Wylie

We consider non-cooperative binding, so-called 'temperature 1', in deterministic or directed (called here confluent) tile self-assembly systems in two dimensions and show a necessary and sufficient condition for such system to have an…

Computational Complexity · Computer Science 2022-02-11 Jérôme Durand-Lose , Hendrik Jan Hoogeboom , Nataša Jonoska

Winfree's abstract Tile Assembly Model (aTAM) is a model of molecular self-assembly of DNA complexes known as tiles, which float freely in solution and attach one at a time to a growing "seed" assembly based on specific binding sites on…

Computational Complexity · Computer Science 2015-03-17 Ho-Lin Chen , David Doty , Shinnosuke Seki

In this work we propose a generalization of Winfree's abstract Tile Assembly Model (aTAM) in which tile types are assigned rigid shapes, or geometries, along each tile face. We examine the number of distinct tile types needed to assemble…

Computational Geometry · Computer Science 2015-03-19 Bin Fu , Matthew J. Patitz , Robert T. Schweller , Bobby Sheline

Working in a three-dimensional variant of Winfree's abstract Tile Assembly Model, we show that, for an arbitrary finite, connected shape $X \subset \mathbb{Z}^2$, there is a tile set that uniquely self-assembles into a 3D representation of…

Computational Geometry · Computer Science 2015-07-24 David Furcy , Scott M. Summers

In this paper we show that passive self-assembly in the context of the tile self-assembly model is capable of performing fuel efficient, universal computation. The tile self-assembly model is a premiere model of self-assembly in which…

Data Structures and Algorithms · Computer Science 2012-08-09 Robert Schweller , Michael Sherman

Self-assembly refers to the process by which small, simple components mix and combine to form complex structures using only local interactions. Designed as a hybrid between tile assembly models and cellular automata, the Tile Automata (TA)…

Emerging Technologies · Computer Science 2019-06-06 John Calvin Alumbaugh , Joshua J. Daymude , Erik D. Demaine , Matthew J. Patitz , Andrea W. Richa

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

Algorithmic self-assembly occurs when disorganized components autonomously combine to form structures and, by their design and the dynamics of the system, are forced to follow the execution of algorithms. Motivated by applications in…

Computational Geometry · Computer Science 2023-05-05 Daniel Hader , Matthew J. Patitz

We investigate a fundamental question regarding a benchmark class of shapes in one of the simplest, yet most widely utilized abstract models of algorithmic tile self-assembly. Specifically, we study the directed tile complexity of a $k…

Data Structures and Algorithms · Computer Science 2020-07-23 David Furcy , Scott M. Summers , Logan Withers

We use analytic theory and computer simulation to study patterns formed during the growth of two-component assemblies in 2D and 3D. We show that these patterns undergo a nonequilibrium phase transition, at a particular growth rate, between…

Statistical Mechanics · Physics 2014-05-12 Stephen Whitelam , Lester O. Hedges , Jeremy D. Schmit

In this paper, we work in a 2D version of the probabilistic variant of Winfree's abstract Tile Assembly Model defined by Chandran, Gopalkrishnan and Reif (SICOMP 2012) in which attaching tiles are sampled uniformly with replacement. First,…

Data Structures and Algorithms · Computer Science 2024-08-13 David Furcy , Scott M. Summers

The well-studied Two-Handed Tile Assembly Model (2HAM) is a model of tile assembly in which pairs of large assemblies can bind, or self-assemble, together. In order to bind, two assemblies must have matching glues that can simultaneously…

Computational Geometry · Computer Science 2014-08-22 Erik D. Demaine , Matthew J. Patitz , Trent A. Rogers , Robert T. Schweller , Scott M. Summers , Damien Woods

Algorithmic self-assembly, a generalization of crystal growth processes, has been proposed as a mechanism for autonomous DNA computation and for bottom-up fabrication of complex nanostructures. A `program' for growing a desired structure…

Materials Science · Physics 2010-01-08 Rebecca Schulman , Erik Winfree

Tile-based self-assembly systems are capable of universal computation and algorithmically-directed growth. Systems capable of such behavior typically make use of "glue cooperation" in which the glues on at least $2$ sides of a tile must…

Emerging Technologies · Computer Science 2019-03-15 Daniel Hader , Matthew J. Patitz

This paper concerns the self-assembly of scaled-up versions of arbitrary finite shapes. We work in the multiple temperature model that was introduced by Aggarwal, Cheng, Goldwasser, Kao, and Schweller (Complexities for Generalized Models of…

Computational Complexity · Computer Science 2009-09-30 Scott M. Summers

We prove that the abstract Tile Assembly Model (aTAM) of nanoscale self-assembly is intrinsically universal. This means that there is a single tile assembly system U that, with proper initialization, simulates any tile assembly system T.…

Data Structures and Algorithms · Computer Science 2012-04-10 David Doty , Jack H. Lutz , Matthew J. Patitz , Robert T. Schweller , Scott M. Summers , Damien Woods

We consider the tile self-assembly model and how tile complexity can be eliminated by permitting the temperature of the self-assembly system to be adjusted throughout the assembly process. To do this, we propose novel techniques for…

Computational Complexity · Computer Science 2007-05-23 Ming-Yang Kao , Robert Schweller