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Convolutional neural networks (CNNs) have yielded the excellent performance in a variety of computer vision tasks, where CNNs typically adopt a similar structure consisting of convolution layers, pooling layers and fully connected layers.…

Neural and Evolutionary Computing · Computer Science 2016-09-13 Hengyue Pan , Hui Jiang

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2017-10-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

This manuscript delves into the intersection of genomics and phenotypic prediction, focusing on the statistical innovation required to navigate the complexities introduced by noisy covariates and confounders. The primary emphasis is on the…

Methodology · Statistics 2024-11-15 Upama Paul Chowdhury , Ronit Bhattacharjee , Susmita Das , Abhik Ghosh

Uplift modeling is a causal learning technique that estimates subgroup-level treatment effects. It is commonly used in industry and elsewhere for tasks such as targeting ads. In a typical setting, uplift models can take thousands of…

Machine Learning · Computer Science 2022-07-15 Zhenyu Zhao , Yumin Zhang , Totte Harinen , Mike Yung

Recent advances in genomic sequencing technology have resulted in an abundance of genome sequence data. Despite the progress in interpreting those data, there remains a broad scope for their translation into clinical and societal benefits.…

Genomics · Quantitative Biology 2021-12-13 Abhinav Jain , Greg Slabaugh , Deepti Gurdasani

Student repetition in secondary education imposes significant resource burdens, particularly in resource-constrained contexts. Addressing this challenge, this study introduces a unified machine learning framework that simultaneously…

Artificial Intelligence · Computer Science 2026-03-03 Mwayi Sonkhanani , Symon Chibaya , Clement N. Nyirenda

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

The Hopfield model is a pioneering neural network model with associative memory retrieval. The analytical solution of the model in mean field limit revealed that memories can be retrieved without any error up to a finite storage capacity of…

Disordered Systems and Neural Networks · Physics 2017-10-31 Do-Hyun Kim , Jinha Park , B. Kahng

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

The proposed method, Discriminator Guidance, aims to improve sample generation of pre-trained diffusion models. The approach introduces a discriminator that gives explicit supervision to a denoising sample path whether it is realistic or…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Dongjun Kim , Yeongmin Kim , Se Jung Kwon , Wanmo Kang , Il-Chul Moon

In fields such as medicine and drug discovery, the ultimate goal of a classification is not to guess a class, but to choose the optimal course of action among a set of possible ones, usually not in one-one correspondence with the set of…

Machine Learning · Computer Science 2023-02-22 K. Dyrland , A. S. Lundervold , P. G. L. Porta Mana

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

One of the most significant current discussions in the field of data mining is classifying imbalanced data. In recent years, several ways are proposed such as algorithm level (internal) approaches, data level (external) techniques, and…

Machine Learning · Computer Science 2021-06-03 Maliheh Roknizadeh , Hossein Monshizadeh Naeen

Prediction and discovery of new materials with desired properties are at the forefront of quantum science and technology research. A major bottleneck in this field is the computational resources and time complexity related to finding new…

Recent research has established a connection between modern Hopfield networks (HNs) and transformer attention heads, with guarantees of exponential storage capacity. However, these models still face challenges scaling storage efficiently.…

Machine Learning · Computer Science 2025-04-11 Saul Santos , António Farinhas , Daniel C. McNamee , André F. T. Martins

Despite their growing capabilities, language models still frequently reproduce content from their training data, generate repetitive text, and favor common grammatical patterns and vocabulary. A possible cause is the decoding strategy: the…

Computation and Language · Computer Science 2026-01-15 Giorgio Franceschelli , Mirco Musolesi

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

Accurate prediction of crop states (e.g., phenology stages and cold hardiness) is essential for timely farm management decisions such as irrigation, fertilization, and canopy management to optimize crop yield and quality. While traditional…

Artificial Intelligence · Computer Science 2026-05-20 William Solow , Paola Pesantez-Cabrera , Markus Keller , Lav Khot , Sandhya Saisubramanian , Alan Fern