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Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

Imbalanced datasets are ubiquitous. Classification performance on imbalanced datasets is generally poor for the minority class as the classifier cannot learn decision boundaries well. However, in sensitive applications like fraud detection,…

Machine Learning · Computer Science 2019-10-25 Vishwa Karia , Wenhao Zhang , Arash Naeim , Ramin Ramezani

A Hopfield network is an auto-associative, distributive model of neural memory storage and retrieval. A form of error-correcting code, the Hopfield network can learn a set of patterns as stable points of the network dynamic, and retrieve…

Neurons and Cognition · Quantitative Biology 2014-07-24 Ila Fiete , David J. Schwab , Ngoc M. Tran

Machine learning holds tremendous promise for transforming the fundamental practice of scientific discovery by virtue of its data-driven nature. With the ever-increasing stream of research data collection, it would be appealing to…

Machine Learning · Computer Science 2024-03-06 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai

Automatic classification of Human Epithelial Type-2 (HEp-2) cells staining patterns is an important and yet a challenging problem. Although both shallow and deep methods have been applied, the study of deep convolutional networks (CNNs) on…

Computer Vision and Pattern Recognition · Computer Science 2018-02-15 Hongwei Li , Wei-Shi Zheng , Jianguo Zhang

We introduce an Outlier-Efficient Modern Hopfield Model (termed $\mathrm{OutEffHop}$) and use it to address the outlier inefficiency problem of {training} gigantic transformer-based models. Our main contribution is a novel associative…

Machine Learning · Computer Science 2024-06-28 Jerry Yao-Chieh Hu , Pei-Hsuan Chang , Robin Luo , Hong-Yu Chen , Weijian Li , Wei-Po Wang , Han Liu

Statistical power is a measure of the replicability of a categorical hypothesis test. Formally, it is the probability of detecting an effect, if there is a true effect present in the population. Hence, optimizing statistical power as a…

Computation · Statistics 2023-02-21 Abhishek K. Umrawal , Sean P. Lane , Erin P. Hennes

Traditionally, signal classification is a process in which previous knowledge of the signals is needed. Human experts decide which features are extracted from the signals, and used as inputs to the classification system. This requirement…

Neural and Evolutionary Computing · Computer Science 2019-04-11 Daniel Rivero , Enrique Fernandez-Blanco , Julian Dorado , Alejandro Pazos

The aim of this paper is to provide a new method for the detection of either favored or avoided distances between genomic events along DNA sequences. These events are modeled by a Hawkes process. The biological problem is actually complex…

Statistics Theory · Mathematics 2010-11-11 Patricia Reynaud-Bouret , Sophie Schbath

Data-driven predictive methods which can efficiently and accurately transform protein sequences into biologically active structures are highly valuable for scientific research and medical development. Determining accurate folding landscape…

We introduce Graph Hopfield Networks, whose energy function couples associative memory retrieval with graph Laplacian smoothing for node classification. Gradient descent on this joint energy yields an iterative update interleaving Hopfield…

Machine Learning · Computer Science 2026-03-05 Abinav Rao , Alex Wa , Rishi Athavale

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

This study proposes an efficient neural network with convolutional layers to classify significantly class-imbalanced clinical data. The data are curated from the National Health and Nutritional Examination Survey (NHANES) with the goal of…

Quantitative Methods · Quantitative Biology 2020-04-24 Aniruddha Dutta , Tamal Batabyal , Meheli Basu , Scott T. Acton

Computer vision-based methods have valuable use cases in precision medicine, and recognizing facial phenotypes of genetic disorders is one of them. Many genetic disorders are known to affect faces' visual appearance and geometry. Automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Ömer Sümer , Fabio Hellmann , Alexander Hustinx , Tzung-Chien Hsieh , Elisabeth André , Peter Krawitz

We propose and analyze a new variation of the so-called {\em exponential Hopfield model}, a recently introduced family of associative neural networks with unprecedented storage capacity. Our construction is based on a cost function defined…

Disordered Systems and Neural Networks · Physics 2025-09-09 Linda Albanese , Andrea Alessandrelli , Adriano Barra , Peter Sollich

Inference after model selection has been an active research topic in the past few years, with numerous works offering different approaches to addressing the perils of the reuse of data. In particular, major progress has been made recently…

Methodology · Statistics 2020-06-02 Snigdha Panigrahi , Jonathan Taylor , Asaf Weinstein

Neuroscience has recently made much progress, expanding the complexity of both neural-activity measurements and brain-computational models. However, we lack robust methods for connecting theory and experiment by evaluating our new big…

Quantitative Methods · Quantitative Biology 2023-07-06 Heiko H. Schütt , Alexander D. Kipnis , Jörn Diedrichsen , Nikolaus Kriegeskorte

The multispecies coalescent process models the genealogical relationships of genes sampled from several species, enabling useful predictions about phenomena such as the discordance between the gene tree and the species phylogeny due to…

Populations and Evolution · Quantitative Biology 2020-12-11 Jakub Truszkowski , Celine Scornavacca , Fabio Pardi

Whole and targeted sequencing of human genomes is a promising, increasingly feasible tool for discovering genetic contributions to risk of complex diseases. A key step is calling an individual's genotype from the multiple aligned short read…

Applications · Statistics 2012-06-29 Baiyu Zhou , Alice S. Whittemore

Classes, as fundamental elements of Computer Vision, have been extensively studied within incremental learning frameworks. In contrast, tokens, which play essential roles in many research fields, exhibit similar characteristics of growth,…

Machine Learning · Computer Science 2025-11-19 Jiaxin Qi , Yan Cui , Jianqiang Huang , Gaogang Xie