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Building a virtual cell capable of accurately simulating cellular behaviors in silico has long been a dream in computational biology. We introduce CellFlux, an image-generative model that simulates cellular morphology changes induced by…

Every volumetric velocimetry measurements based on tracer (particles, bubbles, etc.) detection can be strongly influenced by the optical screening phenomenon. It has to be taken into account when the the statistical properties associated to…

Fluid Dynamics · Physics 2014-07-28 Tristan Cambonie , Jean-Luc Aider

Single-pixel cameras based on the concepts of compressed sensing (CS) leverage the inherent structure of images to retrieve them with far fewer measurements and operate efficiently over a significantly broader spectral range than…

Computer Vision and Pattern Recognition · Computer Science 2016-06-17 Qiang Guo , Hongwei Chen , Yuxi Wang , Yong Guo , Peng Liu , Xiurui Zhu , Zheng Cheng , Zhenming Yu , Minghua Chen , Sigang Yang , Shizhong Xie

We present a new technique for obtaining simultaneous multimodal quantitative phase and fluorescence microscopy of biological cells, providing both quantitative phase imaging and molecular specificity using a single camera. Our system is…

Optics · Physics 2019-04-03 Yoav N. Nygate , Gyanendra Singh , Itay Barnea , Natan T. Shaked

Significance: Diffuse in-vivo Flow Cytometry (DiFC) is an emerging fluorescence sensing method to non-invasively detect labeled circulating cells in-vivo. However, due to Signal-to-Noise Ratio (SNR) constraints largely attributed to…

Medical Physics · Physics 2023-08-04 Giles Blaney , Fernando Ivich , Angelo Sassaroli , Mark Niedre , Sergio Fantini

Three-dimensional molecular imaging of living cells is essential for unraveling cellular metabolism and response to therapies. However, existing volumetric methods, including fluorescence microscopy and quantitative phase imaging, either…

Optical flow is inherently a 2D search problem, and thus the computational complexity grows quadratically with respect to the search window, making large displacements matching infeasible for high-resolution images. In this paper, we take…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Haofei Xu , Jiaolong Yang , Jianfei Cai , Juyong Zhang , Xin Tong

Experimental characterization of blood flow in living organisms is crucial for understanding the development and function of cardiovascular systems, but there have been no techniques reported for snapshot imaging of thick samples in large…

Despite remarkable progress in video generation, maintaining long-term scene consistency upon revisiting previously explored areas remains challenging. Existing solutions rely either on explicitly constructing 3D geometry, which suffers…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Jia Li , Han Yan , Yihang Chen , Siqi Li , Xibin Song , Yifu Wang , Jianfei Cai , Tien-Tsin Wong , Pan Ji

Tracking objects in 3D space and predicting their 6DoF pose is an essential task in computer vision. State-of-the-art approaches often rely on object texture to tackle this problem. However, while they achieve impressive results, many…

Computer Vision and Pattern Recognition · Computer Science 2022-03-11 Manuel Stoiber , Martin Sundermeyer , Rudolph Triebel

Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…

Absolute quantity imaging of biomolecules on a single cell level is critical for measurement assurance in biosciences and bioindustries. While infrared (IR) transmission microscopy is a powerful label-free imaging modality capable of…

Quantitative Methods · Quantitative Biology 2024-03-29 Yow-Ren Chang , Seong-Min Kim , Young Jong Lee

Event-based cameras can overpass frame-based cameras limitations for important tasks such as high-speed motion detection during self-driving cars navigation in low illumination conditions. The event cameras' high temporal resolution and…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Haixin Sun , Minh-Quan Dao , Vincent Fremont

Flow-matching generative models are increasingly used to simulate cell responses to biological perturbations. However, the design space for building such models is large and underexplored. We systematically analyse the design space of flow…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Charles Jones , Emmanuel Noutahi , Jason Hartford , Cian Eastwood

Chlorophyll fluorescence (CF) is a key indicator to study plant physiology or photosynthesis efficiency. Conventionally, CF is characterized by fluorometers, which only allows ensemble measurement through wide-field detection. For imaging…

Biological Physics · Physics 2016-11-10 Yi-Chin Tseng , Shi-Wei Chu

Ultrafast 3D imaging is indispensable for visualizing complex and dynamic biological processes. Conventional scanning-based techniques necessitate an inherent trade-off between acquisition speed and space-bandwidth product (SBP). Emerging…

We present a unified formulation and model for three motion and 3D perception tasks: optical flow, rectified stereo matching and unrectified stereo depth estimation from posed images. Unlike previous specialized architectures for each…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Haofei Xu , Jing Zhang , Jianfei Cai , Hamid Rezatofighi , Fisher Yu , Dacheng Tao , Andreas Geiger

Compressed streak imaging (CSI) is a computational imaging strategy that can acquire video at over 150 trillion frames per second. Despite this achievement, CSI faces challenges in detecting subtle intensity fluctuations in slow-moving,…

In fluid flow imaging, intensity gradients are a good measure of spatial variations in scalar properties, which play an important role in controlling transport processes. However, current flow imaging techniques exhibit system-limited…

Optics · Physics 2025-10-22 Hy Cao , Abhishek Saha , Lisa V. Poulikakos

Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…