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In language production, humans are confronted with considerable word selection demands. Often, we must select a word from among similar, acceptable, and competing alternative words in order to construct a sentence that conveys an intended…

Neurons and Cognition · Quantitative Biology 2018-02-01 John D. Medaglia , Denise Y. Harvey , Nicole White , Danielle S. Bassett , Roy H. Hamilton

Epilepsy is a neurological disorder with recurrent seizures of complexity and randomness. Until now, the mechanism of epileptic randomness has not been fully elucidated. Inspired by the recent finding that astrocyte GTPase-activating…

Neurons and Cognition · Quantitative Biology 2024-06-19 JiaJia Li , Peihua Feng , Liang Zhao , Junying Chen , Mengmeng Du , Yangyang Yu , Jian Song , Ying Wu

We localize the sources of brain activity of children with epilepsy based on EEG recordings acquired during a visual discrimination working memory task. For the numerical solution of the inverse problem, with the aid of age-specific MRI…

Neurons and Cognition · Quantitative Biology 2023-03-16 Evangelos Galaris , Ioannis Gallos , Ivan Myatchin , Lieven Lagae , Constantinos Siettos

Anti-seizure medications (ASMs) are the primary treatment for epilepsy, yet medication tapering effects have not been investigated in a dose, region, and time-dependent manner, despite their potential impact on research and clinical…

Epileptic seizures are considered as abnormally hypersynchronous neuronal activities of the brain. Do hypersynchronous neuronal activities in a brain region lead to seizure or the hypersynchronous activities take place due to the…

Neurons and Cognition · Quantitative Biology 2013-01-08 Kaushik Majumdar , Pradeep D. Prasad , Shailesh Verma

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

Episodic memory -- the ability to recall specific events grounded in time and space -- is a cornerstone of human cognition, enabling not only coherent storytelling, but also planning and decision-making. Despite their remarkable…

Computation and Language · Computer Science 2025-01-24 Alexis Huet , Zied Ben Houidi , Dario Rossi

The theta rhythm is important for many cognitive functions including spatial processing, memory encoding, and memory recall. The information processing underlying these functions is thought to rely on consistent, phase-specific spiking…

Neurons and Cognition · Quantitative Biology 2025-10-16 Oleg Makarenkov , Marianne Bezaire , Michael Hasselmo

Real time seizure detection is a fundamental problem in computational neuroscience towards diagnosis and treatment's improvement of epileptic disease. We propose a real-time computational method for tracking and detection of epileptic…

Quantitative Methods · Quantitative Biology 2024-06-17 Ximena Fernández , Diego Mateos

Sampling considerations limit the experimental conditions under which information theoretic analyses of neurophysiological data yield reliable results. We develop a procedure for computing the full temporal entropy and information of…

Biological Physics · Physics 2009-11-06 Simon R. Schultz , Stefano Panzeri

Time irreversibility (temporal asymmetry) is one of fundamental properties that characterize the nonlinearity of complex dynamical processes, and our brain is a typical complex dynamical system manifested with nonlinearity. Two…

Neurons and Cognition · Quantitative Biology 2020-03-10 Yao Wen-po , Yao wen-li , Dai Jia-fei , Wang Jun

By recording multiple cells simultaneously, electrophysiologists have found evidence for repeating spatiotemporal spike patterns, which can carry information. How this information is extracted by downstream neurons is unclear. In this…

Neural and Evolutionary Computing · Computer Science 2017-07-05 Timothée Masquelier

To minimize functional morbidity associated with brain surgery, new preventive approaches (also referred to as "prehabilitation") by using motor-imagery-based computer interfaces (MI-BCIs) can be utilized. To achieve successful MI-BCI…

Neurons and Cognition · Quantitative Biology 2017-08-03 Milena Korostenskaja , Christoph Kapeller , Ki H Lee , Christoph Guger , James Baumgartner , Eduardo M. Castillo

Temporal lobe surgical resection brings seizure remission in up to 80% of patients, with long-term complete seizure freedom in 41%. However, it is unclear how surgery impacts on the structural white matter network, and how the network…

Neurons and Cognition · Quantitative Biology 2020-09-30 Peter N Taylor , Nishant Sinha , Yujiang Wang , Sjoerd B Vos , Jane de Tisi , Anna Miserocchi , Andrew W McEvoy , Gavin P Winston , John S Duncan

Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae. Blast pressure waves can cause TBI without penetrating wounds or blunt force…

Medical Physics · Physics 2008-08-12 Amy Courtney , Michael Courtney

In-context learning is governed by both temporal and semantic relationships, shaping how Large Language Models (LLMs) retrieve contextual information. Analogous to human episodic memory, where the retrieval of specific events is enabled by…

Computation and Language · Computer Science 2025-10-28 Anooshka Bajaj , Deven Mahesh Mistry , Sahaj Singh Maini , Yash Aggarwal , Zoran Tiganj

Epilepsy is a network disease. The epileptic network usually involves spatially distributed brain regions. In this context, noninvasive M/EEG source connectivity is an emerging technique to identify functional brain networks at cortical…

Neurons and Cognition · Quantitative Biology 2016-08-18 Mahmoud Hassan , Isabelle Merlet , Ahmad Mheich , Aya Kabbara , Arnaud Biraben , Anca Nica , Fabrice Wendling

Spike-timing-dependent plasticity (STDP) with asymmetric learning windows is commonly found in the brain and useful for a variety of spike-based computations such as input filtering and associative memory. A natural consequence of STDP is…

Neurons and Cognition · Quantitative Biology 2012-07-13 Naoki Masuda , Hiroshi Kori

The Thrombolysis in Cerebral Infarction (TICI) score is an important metric for reperfusion therapy assessment in acute ischemic stroke. It is commonly used as a technical outcome measure after endovascular treatment (EVT). Existing TICI…

Precise spatio-temporal patterns of neuronal action potentials underly e.g. sensory representations and control of muscle activities. However, it is not known how the synaptic efficacies in the neuronal networks of the brain adapt such that…

Neurons and Cognition · Quantitative Biology 2015-02-24 Christian Albers , Maren Westkott , Klaus Pawelzik