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The vertebrate hippocampus is believed to use recurrent connectivity in area CA3 to support episodic memory recall from partial cues. This brain area also contains place cells, whose location-selective firing fields implement maps…

Neurons and Cognition · Quantitative Biology 2025-07-11 Zhaoze Wang , Ronald W. Di Tullio , Spencer Rooke , Vijay Balasubramanian

Epilepsy and psychogenic non-epileptic seizures often present with similar seizure-like manifestations but require fundamentally different management strategies. Misdiagnosis is common and can lead to prolonged diagnostic delays,…

Computation and Language · Computer Science 2026-03-31 Shuang Zhou , Kai Yu , Zaifu Zhan , Huixue Zhou , Min Zeng , Feng Xie , Zhiyi Sha , Rui Zhang

Identifying abnormal electroencephalographic activity is crucial in diagnosis and treatment of epilepsy. Recent studies showed that decomposing brain activity into periodic (oscillatory) and aperiodic (trend across all frequencies)…

Neurons and Cognition · Quantitative Biology 2023-10-11 Csaba Kozma , Gabrielle Schroeder , Tom Owen , Jane de Tisi , Andrew W. McEvoy , Anna Miserocchi , John Duncan , Yujiang Wang , Peter N. Taylor

Brain computer interfaces systems are controlled by users through neurophysiological input for a variety of applications including communication, environmental control, motor rehabilitation, and cognitive training. Although individuals with…

Human-Computer Interaction · Computer Science 2021-11-25 Deirdre McLaughlin , Daniel Klee , Tab Memmott , Betts Peters , Jack Wiedrick , Melanie Fried-Oken , Barry Oken

Damage to the white matter underlying the left posterior temporal lobe leads to deficits in multiple language functions. The posterior temporal white matter may correspond to a bottleneck where both dorsal and ventral language pathways are…

Neurons and Cognition · Quantitative Biology 2016-09-08 Joseph C. Griffis , Rodolphe Nenert , Jane B. Allendorfer , Jerzy P. Szaflarski

Aphasia, a language disorder primarily caused by a stroke, is traditionally diagnosed using behavioral language tests. However, these tests are time-consuming, require manual interpretation by trained clinicians, suffer from low ecological…

Signal Processing · Electrical Eng. & Systems 2024-01-22 Pieter De Clercq , Corentin Puffay , Jill Kries , Hugo Van Hamme , Maaike Vandermosten , Tom Francart , Jonas Vanthornhout

Patients with idiopathic generalised epilepsy (IGE) typically have normal conventional magnetic resonance imaging (MRI), hence MRI based diagnosis is challenging. Anatomical abnormalities underlying brain dysfunctions in IGE are unclear and…

Neurons and Cognition · Quantitative Biology 2020-09-30 Nishant Sinha , Yujiang Wang , Justin Dauwels , Marcus Kaiser , Thomas Thesen , Rob Forsyth , Peter Neal Taylor

Given the hard problem of consciousness (Chalmers, 1995) there are no brain electrophysiological correlates of the subjective experience (the felt quality of redness or the redness of red, the experience of dark and light, the quality of…

Neurons and Cognition · Quantitative Biology 2021-03-08 Vitor Manuel Dinis Pereira

Current theories of language recovery after stroke are limited by a reliance on small studies. Here, we aimed to test predictions of current theory and resolve inconsistencies regarding right hemispheric contributions to long-term recovery.…

Neurons and Cognition · Quantitative Biology 2017-01-13 Joseph C. Griffis , Rodolphe Nenert , Jane B. Allendorfer , Jennifer Vannest , Scott Holland , Aimee Dietz , Jerzy P. Szaflarski

The oscillatory nature of the cortical local field potential (LFP) is commonly interpreted as a reflection of synchronized network activity, but its relationship to observed transient coincident firing of neurons on the millisecond…

Neurons and Cognition · Quantitative Biology 2011-11-24 Michael Denker , Sébastien Roux , Henrik Lindén , Markus Diesmann , Alexa Riehle , Sonja Grün

The use of EEG signal to diagnose several brain abnormalities is well-established in the literature. Particularly, epileptic seizure can be detected using EEG signals and several works were done in this field. The joint time-frequency…

Signal Processing · Electrical Eng. & Systems 2020-01-24 Abdullah Othman , Mohamed A. Deriche

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

In this study, we present a deep learning framework that learns complex spatio-temporal correlation structures of EEG signals through a Spatio-Temporal Attention Network (STAN) for accurate predictions of onset of seizures for Epilepsy…

Signal Processing · Electrical Eng. & Systems 2025-11-06 Zan Li , Kyongmin Yeo , Wesley Gifford , Lara Marcuse , Madeline Fields , Bülent Yener

This paper studies the error metric selection for long-term memory learning in sequence modelling. We examine the bias towards short-term memory in commonly used errors, including mean absolute/squared error. Our findings show that all…

Machine Learning · Computer Science 2023-07-24 Shida Wang , Zhanglu Yan

Distinguishing acute ischemic strokes (AIS) from stroke mimics (SMs), particularly in cases involving medium and small vessel occlusions, remains a significant diagnostic challenge. While computed tomography (CT) based protocols are…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Marijn Borghouts , Richard McKinley , Manuel Köstner , Josien Pluim , Roland Wiest , Ruisheng Su

Large language models are known to memorize parts of their training data, posing risk of copyright violations. To systematically examine this risk, we pretrain language models (1B/3B/8B) from scratch on 83B tokens, mixing web-scale data…

Computation and Language · Computer Science 2025-05-29 Yixuan Xu , Antoni-Joan Solergibert i Llaquet , Antoine Bosselut , Imanol Schlag

The accurate diagnosis and assessment of neurodegenerative disease and traumatic brain injuries (TBI) remain open challenges. Both cause cognitive and functional deficits due to focal axonal swellings (FAS), but it is difficult to deliver a…

Neurons and Cognition · Quantitative Biology 2016-12-15 Bethany Lusch , Jake Weholt , Pedro D. Maia , J. Nathan Kutz

Many tasks require flexibly modifying perception and behavior based on current goals. Humans can retrieve episodic memories from days to years ago, using them to contextualize and generalize behaviors across novel but structurally related…

Neural and Evolutionary Computing · Computer Science 2025-12-22 Yicong Zheng , Nora Wolf , Charan Ranganath , Randall C. O'Reilly , Kevin L. McKee

In drug-resistant epilepsy, presurgical evaluation of epilepsy can be considered. Magnetoencephalography (MEG) has been shown to be an effective exam to inform the localization of the epileptogenic zone through the localization of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Pauline Mouches , Julien Jung , Armand Demasson , Agnès Guinard , Romain Bouet , Rosalie Marchal , Romain Quentin

EEG-correlated fMRI analysis is widely used to detect regional blood oxygen level dependent fluctuations that are significantly synchronized to interictal epileptic discharges, which can provide evidence for localizing the ictal onset zone.…

Signal Processing · Electrical Eng. & Systems 2020-05-04 Simon Van Eyndhoven , Patrick Dupont , Simon Tousseyn , Nico Vervliet , Wim Van Paesschen , Sabine Van Huffel , Borbála Hunyadi