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Background: We sought to determine if ripple oscillations (80-120Hz), detected in intracranial EEG (iEEG) recordings of epilepsy patients, correlate with an enhancement or disruption of verbal episodic memory encoding. Methods: We defined…

The Electrocardiography Brain Perfusion index (EBPi) is a novel electrocardiography (ECG)-based metric that may function as a proxy for cerebral blood flow (CBF). We investigated the spatio-temporal correlation between EBPi and epileptic…

To discuss the salient role of the statistical memory effects in the human brain functioning we have analyzed a set of stochastic memory quantifiers that reflects the dynamical characteristics of neuromagnetic brain responses to a…

Medical Physics · Physics 2009-11-13 R. M. Yulmetyev , D. G. Yulmetyeva , E. V. Khusaenova , P. Hänggi , S. Shimojo , J. Bhattacharya

The posterior parietal cortex (PPC) has a unique role in memory retrieval: fMRI and electrocorticography studies suggest that within the ventral PPC (VPC) specifically, there is an anterior-posterior functional divergence between…

Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…

Quantitative Methods · Quantitative Biology 2020-11-17 Md Navid Akbar , Marianna La Rocca , Rachael Garner , Dominique Duncan , Deniz Erdoğmuş

The electroencephalographic (EEG) data intracerebrally recorded from 20 epileptic humans with different brain origins of focal epilepsies or types of seizures, ages and sexes are investigated (nearly 700 million data). Multi channel…

Biological Physics · Physics 2010-02-19 Caglar Tuncay

Epilepsy is a neurological disorder classified as the second most serious neurological disease known to humanity, after stroke. Localization of the epileptogenic zone is an important step for epileptic patient treatment, which starts with…

Seizure and synchronization are related to each other in complex manner. Altered synchrony has been implicated in loss of consciousness during partial seizures. However, the mechanism of altered consciousness following termination of…

Neurons and Cognition · Quantitative Biology 2018-01-30 Puneet Dheer , Sandipan Pati , Srinath Jayachandran , Kaushik Kumar Majumdar

Neurodegenerative diseases and traumatic brain injuries (TBI) are among the main causes of cognitive dysfunction in humans. Both manifestations exhibit the extensive presence of focal axonal swellings (FAS). FAS compromises the information…

Neurons and Cognition · Quantitative Biology 2016-09-27 Melanie Weber , Pedro D. Maia , J. Nathan Kutz

IntroductionThe free and cued selective reminding test is used to identify memory deficits in mild cognitive impairment and demented patients. It allows assessing three processes: encoding, storage, and recollection of verbal episodic…

EEG slowing is reported in various neurological disorders including Alzheimer's, Parkinson's and Epilepsy. Here, we investigate alpha rhythm slowing in individuals with refractory temporal lobe epilepsy (TLE), compared to healthy controls,…

A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with…

Medical Physics · Physics 2012-09-26 Wei Cheng , Xuejuan Zhang , Ge Tian , Jianfeng Feng , Zhengge Wang , Zhiqiang Zhang , GuangMing Lu

Bimodal stimulation, combining cochlear implant (CI) and acoustic input from the opposite ear, typically enhances speech perception but varies due to factors like temporal mismatch. Previously, we used cortical auditory evoked potentials…

Neurons and Cognition · Quantitative Biology 2025-01-29 Hanna Dolhopiatenko , Waldo Nogueira

Structural and functional MRI studies of patients with post-stroke language deficits have contributed substantially to our understanding of how cognitive-behavioral impairments relate to the location of structural damage and to the…

Neurons and Cognition · Quantitative Biology 2016-10-14 Joseph C. Griffis , Rodolphe Nenert , Jane B. Allendorfer , Jerzy P. Szaflarski

Successful epilepsy surgery depends on localising and resecting cerebral abnormalities and networks that generate seizures. Abnormalities, however, may be widely distributed across multiple discontiguous areas. We propose spatially…

Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

Machine Learning · Computer Science 2019-03-20 Diyuan Lu , Jochen Triesch

Status epilepticus (SE) carries risks of morbidity and mortality. Experimental studies have implicated the entorhinal cortex in prolonged seizures; however, studies in large human cohorts are limited. We hypothesised that individuals with…

Neurons and Cognition · Quantitative Biology 2024-08-13 Jonathan Horsley , Yujiang Wang , Callum Simpson , Vyte Janiukstyte , Karoline Leiberg , Beth Little , Jane de Tisi , John Duncan , Peter N. Taylor

Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Muhammad Shoaib Farooq , Aimen Zulfiqar , Shamyla Riaz

Magnetoencephalography (MEG) recordings of patients with epilepsy exhibit spikes, a typical biomarker of the pathology. Detecting those spikes allows accurate localization of brain regions triggering seizures. Spike detection is often…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Pauline Mouches , Thibaut Dejean , Julien Jung , Romain Bouet , Carole Lartizien , Romain Quentin

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy
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