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This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen

Vision-Language Models (VLMs) have achieved remarkable success on multimodal tasks such as image-text retrieval and zero-shot classification, yet they can exhibit demographic biases even when explicit protected attributes are absent during…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Ahsan Habib Akash , Greg Murray , Annahita Amireskandari , Joel Palko , Carol Laxson , Binod Bhattarai , Prashnna Gyawali

We have developed and trained a convolutional neural network to automatically and simultaneously segment optic disc, fovea and blood vessels. Fundus images were normalised before segmentation was performed to enforce consistency in…

Computer Vision and Pattern Recognition · Computer Science 2017-02-03 Jen Hong Tan , U. Rajendra Acharya , Sulatha V. Bhandary , Kuang Chua Chua , Sobha Sivaprasad

Screening for the diagnosis of glaucoma through a fundus image can be determined by the optic cup to disc diameter ratio (CDR), which requires the segmentation of the cup and disc regions. In this paper, we propose two novel approaches,…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Shivam Shah , Nikhil Kasukurthi , Harshit Pande

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Calcium imaging is an important technique for monitoring the activity of thousands of neurons simultaneously. As calcium imaging datasets grow in size, automated detection of individual neurons is becoming important. Here we apply a…

Neurons and Cognition · Quantitative Biology 2016-12-23 Noah J. Apthorpe , Alexander J. Riordan , Rob E. Aguilar , Jan Homann , Yi Gu , David W. Tank , H. Sebastian Seung

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

WHO has declared that more than 2.2 billion people worldwide are suffering from visual disorders, such as media haze, glaucoma, and drusen. At least 1 billion of these cases could have been either prevented or successfully treated, yet they…

Image and Video Processing · Electrical Eng. & Systems 2024-05-30 Yavuz Selim Inan

Convolutional neural networks (CNNs) are a promising technique for automated glaucoma diagnosis from images of the fundus, and these images are routinely acquired as part of an ophthalmic exam. Nevertheless, CNNs typically require a large…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Rui Fan , Christopher Bowd , Nicole Brye , Mark Christopher , Robert N. Weinreb , David Kriegman , Linda M. Zangwill

Computer vision and image processing techniques provide important assistance to physicians and relieve their workload in different tasks. In particular, identifying objects of interest such as lesions and anatomical structures from the…

Medical Physics · Physics 2020-04-23 Meysam Tavakoli , Mahdieh Nazar , Alireza Golestaneh , Faraz Kalantari

The visual analysis of retina and of its vascular characteristics is important in the diagnosis and monitoring of diseases of visual perception. In the related medical diagnoses, the digital processing of the fundus images is used to obtain…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Amelia Carolina Sparavigna

Fundus diseases are major causes of visual impairment and blindness worldwide, especially in underdeveloped regions, where the shortage of ophthalmologists hinders timely diagnosis. AI-assisted fundus image analysis has several advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Yong Liu , Mengtian Kang , Shuo Gao , Chi Zhang , Ying Liu , Shiming Li , Yue Qi , Arokia Nathan , Wenjun Xu , Chenyu Tang , Edoardo Occhipinti , Mayinuer Yusufu , Ningli Wang , Weiling Bai , Luigi Occhipinti

Optical Coherence Tomography (OCT) is a novel and effective screening tool for ophthalmic examination. Since collecting OCT images is relatively more expensive than fundus photographs, existing methods use multi-modal learning to complement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lehan Wang , Weihang Dai , Mei Jin , Chubin Ou , Xiaomeng Li

The annotation of disease severity for medical image datasets often relies on collaborative decisions from multiple human graders. The intra-observer variability derived from individual differences always persists in this process, yet the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-03 Chi Liu , Zongyuan Ge , Mingguang He , Xiaotong Han

Diabetic macular ischemia (DMI), marked by the loss of retinal capillaries in the macular area, contributes to vision impairment in patients with diabetes. Although color fundus photographs (CFPs), combined with artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Qinghua He , Hongyang Jiang , Danqi Fang , Dawei Yang , Truong X. Nguyen , Anran Ran , Clement C. Tham , Simon K. H. Szeto , Sobha Sivaprasad , Carol Y. Cheung

Here, we examine the latest advances in glaucoma detection through Deep Learning (DL) algorithms using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This study focuses on three aspects of DL-based glaucoma…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Mahtab Faraji , Homa Rashidisabet , George R. Nahass , RV Paul Chan , Thasarat S Vajaranant , Darvin Yi

Purpose: To classify eyes as slow or fast glaucoma progressors in patients with primary angle closure glaucoma (PACG) using an integrated approach combining optic nerve head (ONH) structural features and sector-based visual field (VF)…

Purpose: To evaluate nerve fiber layer (NFL) reflectance for glaucoma diagnosis. Methods: Participants were imaged with 4.5X4.5-mm volumetric disc scans using spectral-domain optical coherence tomography (OCT). The normalized NFL…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ou Tan , Liang Liu , Qisheng You , Jie Wang , Aiyin Chen , Eliesa Ing , John C. Morrison , Yali Jia , David Huang

Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern…

Genomics · Quantitative Biology 2022-10-05 Jai Sharma , Vidhyacharan Bhaskar

Diabetic Retinopathy (DR) is a prominent cause of blindness in the world. The early treatment of DR can be conducted from detection of microaneurysms (MAs) which appears as reddish spots in retinal images. An automated microaneurysm…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Noushin Eftekheri , Mojtaba Masoudi , Hamidreza Pourreza , Kamaledin Ghiasi Shirazi , Ehsan Saeedi