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Nucleus segmentation is an important task in medical image analysis. However, machine learning models cannot perform well because there are large amount of clusters of crowded nuclei. To handle this problem, existing approaches typically…

Computer Vision and Pattern Recognition · Computer Science 2020-06-05 Shengcong Chen , Changxing Ding , Dacheng Tao

Image segmentation is an important task in medical imaging. It constitutes the backbone of a wide variety of clinical diagnostic methods, treatments, and computer-aided surgeries. In this paper, we propose a multi-kernel image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Tariq M. Khan , Muhammad Arsalan , Antonio Robles-Kelly , Erik Meijering

Deep Neural Networks (DNNs) have the potential for making various clinical procedures more time-efficient by automating medical image segmentation. Due to their strong, in some cases human-level, performance, they have become the standard…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Martijn M. A. Bosma , Arkadiy Dushatskiy , Monika Grewal , Tanja Alderliesten , Peter A. N. Bosman

For complex segmentation tasks, fully automatic systems are inherently limited in their achievable accuracy for extracting relevant objects. Especially in cases where only few data sets need to be processed for a highly accurate result,…

Computer Vision and Pattern Recognition · Computer Science 2017-09-12 Mario Amrehn , Sven Gaube , Mathias Unberath , Frank Schebesch , Tim Horz , Maddalena Strumia , Stefan Steidl , Markus Kowarschik , Andreas Maier

Deep convolutional neural network (CNN) achieves remarkable performance for medical image analysis. UNet is the primary source in the performance of 3D CNN architectures for medical imaging tasks, including brain tumor segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Parvez Ahmad , Saqib Qamar , Linlin Shen , Adnan Saeed

Colorectal cancer (CRC) is among the top three malignant tumor types in terms of morbidity and mortality. Histopathological images are the gold standard for diagnosing colon cancer. Cellular nuclei instance segmentation and classification,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Liangrui Pan , Lian Wang , Zhichao Feng , Zhujun Xu , Liwen Xu , Shaoliang Peng

Models based on U-like structures have improved the performance of medical image segmentation. However, the single-layer decoder structure of U-Net is too "thin" to exploit enough information, resulting in large semantic differences between…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Haoyuan Chen , Yufei Han , Pin Xu , Yanyi Li , Kuan Li , Jianping Yin

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Deep learning architecture with convolutional neural network (CNN) achieves outstanding success in the field of computer vision. Where U-Net, an encoder-decoder architecture structured by CNN, makes a great breakthrough in biomedical image…

Image and Video Processing · Electrical Eng. & Systems 2023-02-13 Qing Xu , Zhicheng Ma , Na HE , Wenting Duan

Segmentation is one of the most significant steps in image processing. Segmenting an image is a technique that makes it possible to separate a digital image into various areas based on the different characteristics of pixels in the image.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Sina Derakhshandeh , Ali Mahloojifar

Residual network (ResNet) and densely connected network (DenseNet) have significantly improved the training efficiency and performance of deep convolutional neural networks (DCNNs) mainly for object classification tasks. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Mina Jafari , Dorothee Auer , Susan Francis , Jonathan Garibaldi , Xin Chen

Histopathology image analysis is critical yet challenged by the demand of segmenting tissue regions and nuclei instances for tumor microenvironment and cellular morphology analysis. Existing studies focused on tissue semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Qing Xu , Wenting Duan , Zhen Chen

Convolutional neural networks (CNNs) have been successfully applied to medical image classification, segmentation, and related tasks. Among the many CNNs architectures, U-Net and its improved versions based are widely used and achieve…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Henry H. Yu , Xue Feng , Hao Sun , Ziwen Wang

Automated histopathological image analysis plays a vital role in computer-aided diagnosis of various diseases. Among developed algorithms, deep learning-based approaches have demonstrated excellent performance in multiple tasks, including…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Diana Mechtcheriakova , Amirreza Mahbod

Due to its excellent performance, U-Net is the most widely used backbone architecture for biomedical image segmentation in the recent years. However, in our studies, we observe that there is a considerable performance drop in the case of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Jeya Maria Jose , Vishwanath Sindagi , Ilker Hacihaliloglu , Vishal M. Patel

Accurate segmentation of brain tumors plays a key role in the diagnosis and treatment of brain tumor diseases. It serves as a critical technology for quantifying tumors and extracting their features. With the increasing application of deep…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Longfeng Shen , Yanqi Hou , Jiacong Chen , Liangjin Diao , Yaxi Duan

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Inspired by the recent success of Transformers for Natural Language Processing and vision Transformer for Computer Vision, many researchers in the medical imaging community have flocked to Transformer-based networks for various main stream…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Ye Li , Junyu Chen , Se-in Jang , Kuang Gong , Quanzheng Li

Accurate segmentation of different sub-regions of gliomas including peritumoral edema, necrotic core, enhancing and non-enhancing tumor core from multimodal MRI scans has important clinical relevance in diagnosis, prognosis and treatment of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Xue Feng , Nicholas Tustison , Craig Meyer

Semantic, instance, and panoptic segmentations have been addressed using different and specialized frameworks despite their underlying connections. This paper presents a unified, simple, and effective framework for these essentially similar…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Wenwei Zhang , Jiangmiao Pang , Kai Chen , Chen Change Loy