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Although the U-Net architecture has been extensively used for segmentation of medical images, we address two of its shortcomings in this work. Firstly, the accuracy of vanilla U-Net degrades when the target regions for segmentation exhibit…

Breast tumor segmentation is one of the key steps that helps us characterize and localize tumor regions. However, variable tumor morphology, blurred boundary, and similar intensity distributions bring challenges for accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Gongping Chen , Lei Li , JianXun Zhang , Yu Dai

Recently deep neural networks, which require a large amount of annotated samples, have been widely applied in nuclei instance segmentation of H\&E stained pathology images. However, it is inefficient and unnecessary to label all pixels for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-21 Wei Lou , Haofeng Li , Guanbin Li , Xiaoguang Han , Xiang Wan

Medical imaging plays a crucial role in modern healthcare by providing non-invasive visualisation of internal structures and abnormalities, enabling early disease detection, accurate diagnosis, and treatment planning. This study aims to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-25 Walid Ehab , Yongmin Li

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Deep convolutional neural networks have been proven to be very effective in image related analysis and tasks, such as image segmentation, image classification, image generation, etc. Recently many sophisticated CNN based architectures have…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Eshal Zahra , Bostan Ali , Wajahat Siddique

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Wei Lou , Xiang Wan , Guanbin Li , Xiaoying Lou , Chenghang Li , Feng Gao , Haofeng Li

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a deep neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Sen Yang , Jinxi Xiang , Xiyue Wang

Low level features like edges and textures play an important role in accurately localizing instances in neural networks. In this paper, we propose an architecture which improves feature pyramid networks commonly used instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Yongqing Sun , Pranav Shenoy K P , Jun Shimamura , Atsushi Sagata

In clinical practice, regions of interest in medical imaging often need to be identified through a process of precise image segmentation. The quality of this image segmentation step critically affects the subsequent clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-23 João B. S. Carvalho , João A. Santinha , Đorđe Miladinović , Joachim M. Buhmann

Medical image segmentation is crucial for disease diagnosis and monitoring. Though effective, the current segmentation networks such as UNet struggle with capturing long-range features. More accurate models such as TransUNet, Swin-UNet, and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Khaled Alrfou , Tian Zhao

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Automatic medical image segmentation is a crucial topic in the medical domain and successively a critical counterpart in the computer-aided diagnosis paradigm. U-Net is the most widespread image segmentation architecture due to its…

Recently, deep learning has become much more popular in computer vision area. The Convolution Neural Network (CNN) has brought a breakthrough in images segmentation areas, especially, for medical images. In this regard, U-Net is the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Ange Lou , Shuyue Guan , Murray Loew

Due to the wide existence and large morphological variances of nuclei, accurate nuclei instance segmentation is still one of the most challenging tasks in computational pathology. The annotating of nuclei instances, requiring experienced…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

Deep neural networks show high accuracy in theproblem of semantic and instance segmentation of biomedicaldata. However, this approach is computationally expensive. Thecomputational cost may be reduced with network simplificationafter…

Image and Video Processing · Electrical Eng. & Systems 2020-02-18 Alexander Karimov , Artem Razumov , Ruslana Manbatchurina , Ksenia Simonova , Irina Donets , Anastasia Vlasova , Yulia Khramtsova , Konstantin Ushenin

Nuclei segmentation, despite its fundamental role in histopathological image analysis, is still a challenge work. The main challenge of this task is the existence of overlapping areas, which makes separating independent nuclei more…

Image and Video Processing · Electrical Eng. & Systems 2024-07-25 Dinh-Phu Tran , Quoc-Anh Nguyen , Van-Truong Pham , Thi-Thao Tran