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Related papers: Dense Fiber Modeling for 3D-Polarized Light Imagin…

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Three-dimensional Polarized Light Imaging (3D-PLI) is a promising technique to reconstruct the nerve fiber architecture of human post-mortem brains from birefringence measurements of histological brain sections with micrometer resolution.…

Medical Physics · Physics 2017-03-17 Miriam Menzel , Markus Axer , Hans De Raedt , Kristel Michielsen

For developing a detailed network model of the brain based on image reconstructions, it is necessary to spatially resolve crossing nerve fibers. The accuracy hereby depends on many factors, including the spatial resolution of the imaging…

A comprehensive understanding of the organizational principles in the human brain requires, among other factors, well-quantifiable descriptors of nerve fiber architecture. Three-dimensional polarized light imaging (3D-PLI) is a microscopic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Alexander Oberstrass , Sascha E. A. Muenzing , Meiqi Niu , Nicola Palomero-Gallagher , Christian Schiffer , Markus Axer , Katrin Amunts , Timo Dickscheid

The method 3D polarised light imaging (3D-PLI) measures the birefringence of histological brain sections to determine the spatial course of nerve fibres (myelinated axons). While the in-plane fibre directions can be determined with high…

Biological Physics · Physics 2022-04-12 Miriam Menzel , Jan A. Reuter , David Gräßel , Irene Costantini , Katrin Amunts , Markus Axer

Mapping the intricate network of nerve fibers is crucial for understanding brain function. Three-Dimensional Polarized Light Imaging (3D-PLI) and Computational Scattered Light Imaging (ComSLI) map dense nerve fibers in brain sections with…

Medical Physics · Physics 2025-06-03 Franca auf der Heiden , Markus Axer , Katrin Amunts , Miriam Menzel

The neuroimaging technique three-dimensional polarized light imaging (3D-PLI) provides a high-resolution reconstruction of nerve fibres in human post-mortem brains. The orientations of the fibres are derived from birefringence measurements…

Medical Physics · Physics 2015-10-12 Miriam Menzel , Kristel Michielsen , Hans De Raedt , Julia Reckfort , Katrin Amunts , Markus Axer

Understanding the cortical organization of the human brain requires interpretable descriptors for distinct structural and functional imaging data. 3D polarized light imaging (3D-PLI) is an imaging modality for visualizing fiber architecture…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Alexander Oberstrass , Jordan DeKraker , Nicola Palomero-Gallagher , Sascha E. A. Muenzing , Alan C. Evans , Markus Axer , Katrin Amunts , Timo Dickscheid

Comprehensive assessment of the various aspects of the brain's microstructure requires the use of complementary imaging techniques. This includes measuring the spatial distribution of cell bodies (cytoarchitecture) and nerve fibers…

Three dimensional Polarized Light Imaging (3D-PLI) is an optical technique which allows mapping the spatial fiber architecture of fibrous postmortem tissues, at sub-millimeter resolutions. Here, we propose an analytical and fast approach to…

Medical Physics · Physics 2020-12-18 A. Alimi , S. Deslauriers-Gauthier , F. Matuschke , A. Müller , S. E. A. Muenzing , M. Axer , R. Deriche

In many laboratories, conventional bright-field transmission microscopes are available to study the structure and organization principles of fibrous tissue samples, but they usually provide only 2D information. To access the third…

Scattered Light Imaging (SLI) is a novel approach for microscopically revealing the fibre architecture of unstained brain sections. The measurements are obtained by illuminating brain sections from different angles and measuring the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Esteban Vaca , Miriam Menzel , Katrin Amunts , Markus Axer , Timo Dickscheid

The correct reconstruction of individual (crossing) nerve fibers is a prerequisite when constructing a detailed network model of the brain. The recently developed technique Scattered Light Imaging (SLI) allows the reconstruction of crossing…

Biological Physics · Physics 2021-11-30 Miriam Menzel , Marouan Ritzkowski , Jan André Reuter , David Gräßel , Katrin Amunts , Markus Axer

3D-Polarized Light Imaging (3D-PLI) reconstructs nerve fibers in histological brain sections by measuring their birefringence. This study investigates another effect caused by the optical anisotropy of brain tissue - diattenuation. Based on…

Medical Physics · Physics 2017-06-13 Miriam Menzel , Julia Reckfort , Daniel Weigand , Hasan Köse , Katrin Amunts , Markus Axer

3D reconstruction of the fiber connectivity of the rat brain at microscopic scale enables gaining detailed insight about the complex structural organization of the brain. We introduce a new method for registration and 3D reconstruction of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Sharib Ali , Martin Schober , Philipp Schlöme , Katrin Amunts , Markus Axer , Karl Rohr

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

Visual perception relies on inference of 3D scene properties such as shape, pose, and lighting. To understand how visual sensory neurons enable robust perception, it is crucial to characterize their selectivity to such physically…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Pavithra Elumalai , Mohammad Bashiri , Goirik Chakrabarty , Suhas Shrinivasan , Fabian H. Sinz

This paper tackles the problem of estimating 3D body shape of clothed humans from single polarized 2D images, i.e. polarization images. Polarization images are known to be able to capture polarized reflected lights that preserve rich…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Shihao Zou , Xinxin Zuo , Yiming Qian , Sen Wang , Chi Xu , Minglun Gong , Li Cheng

Surface analysis of the cortex is ubiquitous in human neuroimaging with MRI, e.g., for cortical registration, parcellation, or thickness estimation. The convoluted cortical geometry requires isotropic scans (e.g., 1mm MPRAGEs) and good…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Karthik Gopinath , Douglas N. Greve , Sudeshna Das , Steve Arnold , Colin Magdamo , Juan Eugenio Iglesias

Optical neural networks are emerging as a powerful and versatile tool for processing optical signals directly in the optical domain with superior speed, integrability, and functionality. Their application to optical polarization enables…

Optics · Physics 2025-06-24 Alessandro Petrini , Claudio Conti , Davide Pierangeli

Deep learning techniques provide a plausible route towards achieving practical imaging through multimode fibers. The results produced by these methods are often influenced by physical factors like temperature, fiber length, external…

Optics · Physics 2024-03-14 Jawaria Maqbool , Syed Talal Hassan , M. Imran Cheema
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