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Gradual transformation of the epidermal stem cells to corneocytes involves a chain of chronologically well-arranged events that mostly stimulated locally by their neighbors. Cell diversity that observed during the differentiation through…

Tissues and Organs · Quantitative Biology 2008-04-22 A. Mezentsev

Two distinct families of pan-primate endogenous retroviruses, namely HERVL and HERVH, infected primates germline, colonized host genomes, and evolved into the global retroviral genomic regulatory dominion (GRD) operating during human…

Genomics · Quantitative Biology 2025-12-30 Gennadi Glinsky

Different subsystems of organisms adapt over many time scales, such as rapid changes in the nervous system (learning), slower morphological and neurological change over the lifetime of the organism (postnatal development), and change over…

Neural and Evolutionary Computing · Computer Science 2017-07-28 Sam Kriegman , Nick Cheney , Francesco Corucci , Josh C. Bongard

The origin of life is one of the greatest mysteries. The mechanism for the synthesis of DNA is synonymous with the chemical origin of life, and theories have been developed along many lines of reasoning, but resolving all requirements…

Other Quantitative Biology · Quantitative Biology 2020-07-07 Charles D. Schaper

Satellites of asteroids have been discovered in nearly every known small body population, and a remarkable aspect of the known satellites is the diversity of their properties. They tell a story of vast differences in formation and evolution…

Earth and Planetary Astrophysics · Physics 2016-08-31 Kevin J. Walsh , Seth A. Jacobson

All living cells interact dynamically with a constantly changing world. Eukaryotes in particular, evolved radically new ways to sense and react to their environment. These advances enabled new and more complex forms of cellular behavior in…

Biological Physics · Physics 2021-02-01 Kirsty Y. Wan , Gáspár Jékely

Gynandromorphs are creatures where at least two different body sections are a different sex. Bilateral gynandromorphs are half male and half female. Here we develop a theory of gynandromorph ontogeny based on developmental control networks.…

Molecular Networks · Quantitative Biology 2012-12-24 Eric Werner

For more than 3.5 billion years, life experienced dramatic environmental extremes on Earth. These include shifts from oxygen-less to over-oxygenated atmospheres and cycling between hothouse conditions and global glaciations. Meanwhile, an…

Populations and Evolution · Quantitative Biology 2024-06-14 Betul Kacar

The natural evolution of life seems to proceed through steps characterized by phases of relatively rapid changes, followed by longer, more stable periods. In the light of the string-theory derived physical scenario proposed in [1], we…

General Physics · Physics 2007-12-06 Andrea Gregori

Biological systems have evolved to amazingly complex states, yet we do not understand in general how evolution operates to generate increasing genetic and functional complexity. Molecular recognition sites are short genome segments or…

Populations and Evolution · Quantitative Biology 2025-01-06 Tom Röschinger , Roberto Morán Tovar , Simone Pompei , Michael Lässig

How the very first nervous systems evolved remains a fundamental open question. Molecular and genomic techniques have revolutionized our knowledge of the molecular ingredients behind this transition but not yet provided a clear picture of…

Neurons and Cognition · Quantitative Biology 2017-10-31 Ronald A. J. van Elburg , Oltman O. de Wiljes , Michael Biehl , Fred A. Keijzer

An intriguing unanswered question about the evolution of bilateral animals with internal skeletons is how an internal skeleton evolved in the first place. Computational modeling of the development of bilateral symmetric organisms suggests…

Tissues and Organs · Quantitative Biology 2012-07-17 Eric Werner

The metazoan body plan is established during early embryogenesis via collective cell rearrangements and evolutionarily conserved gene networks, as part of a process commonly referred to as gastrulation. While substantial progress has been…

Populations and Evolution · Quantitative Biology 2020-11-24 Kerim Anlas , Vikas Trivedi

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

Asteroids are leftover pieces from the era of planet formation that help us understand conditions in the early Solar System. Unlike larger planetary bodies that were subject to global thermal modification during and subsequent to their…

Earth and Planetary Astrophysics · Physics 2009-06-25 Kevin J. Walsh , Patrick Michel , Derek C. Richardson

Rapid anthropogenic environmental changes, including those due to habitat contamination, degradation, and climate change, have far-reaching effects on biological systems that may outpace animals' adaptive responses (Radchuk et al., 2019).…

Neurons and Cognition · Quantitative Biology 2022-10-17 Angie Michaiel , Amy Bernard

It is has been assumed for over half a century that the earliest animals were obligate aerobes with relatively high oxygen requirements. However, the conserved biochemistry and widespread phylogenetic distribution of anaerobic energy…

Populations and Evolution · Quantitative Biology 2015-05-01 Daniel B. Mills , Lewis M. Ward , CarriAyne Jones , Brittany Sweeten , Michael Forth , Alexander H. Treusch , Donald E. Canfield

The reward system is one of the fundamental drivers of animal behaviors and is critical for survival and reproduction. Despite its importance, the problem of how the reward system has evolved is underexplored. In this paper, we try to…

Neural and Evolutionary Computing · Computer Science 2024-06-24 Yuji Kanagawa , Kenji Doya

Rhythmic and sequential segmentation of the embryonic body plan is a vital developmental patterning process in all vertebrate species. However, a theoretical framework capturing the emergence of dynamic patterns of gene expression from the…

Biological Physics · Physics 2016-10-12 David J. Jörg , Andrew C. Oates , Frank Jülicher

Lampreys are one of the oldest species in the world, living longer than dinosaurs, which is related to the ability to change the sex ratio during their lifespan. In this paper, to understand how sex ratio and food quantity affect the…

Populations and Evolution · Quantitative Biology 2024-07-16 Zuhua Ji , Jiarui Chen , Zihang Wang