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Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables. It has been previously proposed that non-linear…

Neurons and Cognition · Quantitative Biology 2016-04-25 Jeff Hawkins , Subutai Ahmad

The Semantic Theory of Evolution (STE) takes the existence of a number of arbitrary communication codes as a fundamental feature of life, from the genetic code to human cultural communication codes. Their arbitrariness enables, at each…

Artificial Intelligence · Computer Science 2025-07-01 Guido Fioretti

The Earth appears non-chondritic in its abundances of refractory lithophile elements, posing a significant problem for our understanding of its formation and evolution. It has been suggested that this non-chondritic composition may be…

Earth and Planetary Astrophysics · Physics 2015-11-04 Philip J. Carter , Zoë M. Leinhardt , Tim Elliott , Michael J. Walter , Sarah T. Stewart

A major challenge in biology is explaining how novel characters originate, however, the molecular mechanisms that underlie the emergence of evolutionary innovations are unclear. Here we show that while gene expression in the uterus evolves…

Gene regulatory networks (GRN) govern phenotypic adaptations and reflect the trade-offs between physiological responses and evolutionary adaptation that act at different time scales. To identify patterns of molecular function and genetic…

This is an overview of recent research on meteors and the parent bodies from which they are produced. While many meteor showers result from material ejected by comets, two out of the three strongest annual showers (the Geminids and the…

Earth and Planetary Astrophysics · Physics 2022-09-21 Toshihiro Kasuga , David Jewitt

Background: Transposable elements (TEs) have played an important role in the diversification and enrichment of mammalian transcriptomes through various mechanisms such as exonization and intronization (the birth of new exons/introns from…

Genomics · Quantitative Biology 2010-06-17 Noa Sela , Eddo Kim , Gil Ast

Prebiotic molecules, fundamental building blocks for the origin of life, have been found in carbonaceous chondrites. The exogenous delivery of these organic molecules onto the Hadean Earth could have sparked the polymerization of the first…

Earth and Planetary Astrophysics · Physics 2023-01-23 Klaus Paschek , Dmitry A. Semenov , Ben K. D. Pearce , Kevin Lange , Thomas K. Henning , Ralph E. Pudritz

Previous studies have demonstrated the importance of the primary sensory cortex for the detection, discrimination and awareness of visual stimuli, but it is unknown how neuronal populations in this area process detected and undetected…

Neurons and Cognition · Quantitative Biology 2015-12-03 Jorrit S. Montijn , Pieter M. Goltstein , Cyriel M. A. Pennartz

Better understanding the molecular processes contributing to variation in maturation timing is important for Atlantic salmon aquaculture, as early maturation causes considerable financial losses. The m6A RNA methylation is a conserved and…

Genomics · Quantitative Biology 2024-10-28 Ehsan Pashay Ahi , Morgane Frapin , Mikaela Hukkanen , Craig R. Primmer

In this paper we analyse the genetic evolution of a diploid hermaphroditic population, which is modelled by a three-type nonlinear birth-and-death process with competition and Mendelian reproduction. In a recent paper, Collet et al., 2013…

Probability · Mathematics 2017-08-28 Anton Bovier , Rebecca Neukirch

We updated the agent based Monte Carlo code HERITAGE that simulates human evolution within restrictive environments such as interstellar, sub-light speed spacecraft in order to include the effects of population genetics. We incorporated a…

Popular Physics · Physics 2021-02-03 F. Marin , C. Beluffi , F. Fischer

Proteins have evolved through mutations, amino acid substitutions, since life appeared on Earth, some 109 years ago. The study of these phenomena has been of particular significance because of their impact on protein stability, function,…

Biomolecules · Quantitative Biology 2023-10-25 Jorge A. Vila

Within the framework of population genetics we consider the evolution of an asexual haploid population under the effect of a rapidly varying natural selection (microevolution). We focus on the case in which the environment exerting…

Populations and Evolution · Quantitative Biology 2015-06-22 Stefano Bo , Andrea Mazzolini , Antonio Celani

Biological cells and many living organisms are mostly made of liquids and therefore, by analogy with liquid drops, they should exhibit a range of fundamental nonlinear phenomena such as the onset of standing surface waves. Here, we test…

Soft Condensed Matter · Physics 2019-12-18 Ivan S. Maksymov , Andrey Pototsky

We consider evolution of a large population, where fitness of each organism is defined by many phenotypical traits. These traits result from expression of many genes. We propose a new model of gene regulation, where gene expression is…

Populations and Evolution · Quantitative Biology 2016-09-29 John Reinitz , Sergey Vakulenko , Dmitri Grigoriev , Andreas Weber

Understanding the differentiation, a biological process from a multipotent stem or progenitor state to a mature cell is critically important. We develop a theoretical framework to quantify the underlying potential landscape and biological…

Molecular Networks · Quantitative Biology 2012-02-29 Haidong Feng , Jin Wang

A basal animal model is described as an organism similar to a Limpet that is attached to the sea floor living in a reproductive community. Its brain model uses logic cells (gates) to create a high frequency spike generator. Addition logic…

Other Quantitative Biology · Quantitative Biology 2016-12-19 Robert Alan Brown

Globular clusters (GCs) host multiple stellar populations differing in their chemical and dynamical properties. A number of models for the formation of multiple populations predict that the subsystem of second generation (SG) stars is…

Astrophysics of Galaxies · Physics 2026-01-21 Ethan B. White , Enrico Vesperini , Emanuele Dalessandro , Anna Lisa Varri

The zebrafish (\emph{Danio rerio}) is one of the model animals for study of immunology because the dynamics in the adaptive immune system of zebrafish are similar to that in higher animals. In this work, we built a multi-scale model to…

Populations and Evolution · Quantitative Biology 2015-06-04 Keyao Pan , Michael W. Deem
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